Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886506596> ?p ?o ?g. }
- W2886506596 endingPage "894" @default.
- W2886506596 startingPage "885" @default.
- W2886506596 abstract "The aim of this study was to formulate and evaluate the freeze‐dried kit of NOTA‐hexavalent lactoside (NOTA‐HL) for the preparation of 68 Ga‐labeled glycoligand for PET imaging of the asialoglycoprotein receptor (ASGPR). 68 GaCl 3 was obtained from a commercial 68 Ge/ 68 Ga generator. Single‐vial kits of HL were formulated. Optimization of radiolabeling with 68 Ga, various evaluations of NOTA‐HL kits, and in vitro stability study of 68 Ga‐HL were carried out. PET/CT imaging of normal mice injected with 68 Ga‐NOTA‐HL was performed. NOTA‐HL kit was successfully formulated. High radiochemical yields (>95%) were obtained by 68 Ga radiolabeling. The NOTA‐HL kits were stable for at least 12 months, and 68 Ga‐NOTA‐HL exhibited good in vitro stability. PET studies in normal mice revealed high specific accumulation of activity in the liver. The NOTA‐HL kit was developed for fast 68 Ga labeling. 68 Ga‐NOTA‐HL showed high specific uptake in liver. The availability of ready‐to‐use NOTA‐HL kits combined with 68 Ge/ 68 Ga generators would provide an efficient approach for PET imaging of ASGPR." @default.
- W2886506596 created "2018-08-22" @default.
- W2886506596 creator A5002948301 @default.
- W2886506596 creator A5002950506 @default.
- W2886506596 creator A5004974093 @default.
- W2886506596 creator A5012994073 @default.
- W2886506596 creator A5030467912 @default.
- W2886506596 creator A5049484067 @default.
- W2886506596 creator A5054226103 @default.
- W2886506596 creator A5071145021 @default.
- W2886506596 creator A5078339412 @default.
- W2886506596 creator A5080421941 @default.
- W2886506596 date "2018-09-03" @default.
- W2886506596 modified "2023-10-14" @default.
- W2886506596 title "Development of single vial kits for preparation of68Ga-labelled hexavalent lactoside for PET imaging of asialoglycoprotein receptor" @default.
- W2886506596 cites W130254282 @default.
- W2886506596 cites W1610851198 @default.
- W2886506596 cites W1691646448 @default.
- W2886506596 cites W1964170750 @default.
- W2886506596 cites W1967968418 @default.
- W2886506596 cites W1971204572 @default.
- W2886506596 cites W1976347548 @default.
- W2886506596 cites W1976928913 @default.
- W2886506596 cites W1984014884 @default.
- W2886506596 cites W1990076803 @default.
- W2886506596 cites W1995343285 @default.
- W2886506596 cites W2001193192 @default.
- W2886506596 cites W2004291452 @default.
- W2886506596 cites W2009893407 @default.
- W2886506596 cites W2011917162 @default.
- W2886506596 cites W2016189788 @default.
- W2886506596 cites W2019209193 @default.
- W2886506596 cites W2022895790 @default.
- W2886506596 cites W2031681210 @default.
- W2886506596 cites W2033812668 @default.
- W2886506596 cites W2039289432 @default.
- W2886506596 cites W2039572832 @default.
- W2886506596 cites W2043097027 @default.
- W2886506596 cites W2051546995 @default.
- W2886506596 cites W2051778134 @default.
- W2886506596 cites W2052728330 @default.
- W2886506596 cites W2053619565 @default.
- W2886506596 cites W2054411549 @default.
- W2886506596 cites W2077496740 @default.
- W2886506596 cites W2078480870 @default.
- W2886506596 cites W2085543839 @default.
- W2886506596 cites W2089943463 @default.
- W2886506596 cites W2093281717 @default.
- W2886506596 cites W2096688516 @default.
- W2886506596 cites W2101931524 @default.
- W2886506596 cites W2104806146 @default.
- W2886506596 cites W2163137811 @default.
- W2886506596 cites W2175128997 @default.
- W2886506596 cites W2560409769 @default.
- W2886506596 cites W2588852402 @default.
- W2886506596 cites W4211090422 @default.
- W2886506596 cites W4302400124 @default.
- W2886506596 cites W2140966208 @default.
- W2886506596 doi "https://doi.org/10.1002/jlcr.3673" @default.
- W2886506596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30089196" @default.
- W2886506596 hasPublicationYear "2018" @default.
- W2886506596 type Work @default.
- W2886506596 sameAs 2886506596 @default.
- W2886506596 citedByCount "8" @default.
- W2886506596 countsByYear W28865065962019 @default.
- W2886506596 countsByYear W28865065962020 @default.
- W2886506596 countsByYear W28865065962021 @default.
- W2886506596 countsByYear W28865065962022 @default.
- W2886506596 crossrefType "journal-article" @default.
- W2886506596 hasAuthorship W2886506596A5002948301 @default.
- W2886506596 hasAuthorship W2886506596A5002950506 @default.
- W2886506596 hasAuthorship W2886506596A5004974093 @default.
- W2886506596 hasAuthorship W2886506596A5012994073 @default.
- W2886506596 hasAuthorship W2886506596A5030467912 @default.
- W2886506596 hasAuthorship W2886506596A5049484067 @default.
- W2886506596 hasAuthorship W2886506596A5054226103 @default.
- W2886506596 hasAuthorship W2886506596A5071145021 @default.
- W2886506596 hasAuthorship W2886506596A5078339412 @default.
- W2886506596 hasAuthorship W2886506596A5080421941 @default.
- W2886506596 hasConcept C11569505 @default.
- W2886506596 hasConcept C13965031 @default.
- W2886506596 hasConcept C150903083 @default.
- W2886506596 hasConcept C170493617 @default.
- W2886506596 hasConcept C177322064 @default.
- W2886506596 hasConcept C185592680 @default.
- W2886506596 hasConcept C202751555 @default.
- W2886506596 hasConcept C207001950 @default.
- W2886506596 hasConcept C2775842073 @default.
- W2886506596 hasConcept C2776200302 @default.
- W2886506596 hasConcept C2778172261 @default.
- W2886506596 hasConcept C2989005 @default.
- W2886506596 hasConcept C3017724952 @default.
- W2886506596 hasConcept C43617362 @default.
- W2886506596 hasConcept C55493867 @default.
- W2886506596 hasConcept C71924100 @default.
- W2886506596 hasConcept C72092618 @default.
- W2886506596 hasConcept C86803240 @default.
- W2886506596 hasConceptScore W2886506596C11569505 @default.