Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886547942> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2886547942 abstract "Objective— Growth hormone (GH) induces hepatic low-density lipoprotein (LDL) receptors and lowers plasma cholesterol. We characterized the influence of GH treatment on plasma LDL clearance in normal humans and investigated the relative role of LDL receptor (LDLR) activity and stimulation of bile acid synthesis in subjects with different LDLR expression. Methods and Results— Plasma clearance of autologous 125I-LDL was measured before and during 3 weeks of treatment with GH (0.1 IU/kg per day) in 9 healthy young males. Plasma LDL cholesterol was reduced by 13% and the fractional catabolic rate of LDL increased by 27%. More marked changes were seen in a patient with hypopituitarism substituted with GH (0.07 IU/kg per day) for 3 months. In a second study, GH dose-dependently reduced LDL cholesterol and increased Lp(a) levels in 3 groups of males: younger and elderly healthy subjects and heterozygous familial hypercholesterolemia (FH). No effect on bile acid synthesis measured by the plasma marker 7α-hydroxy-4..." @default.
- W2886547942 created "2018-08-22" @default.
- W2886547942 creator A5022507631 @default.
- W2886547942 creator A5030265747 @default.
- W2886547942 creator A5035490163 @default.
- W2886547942 creator A5035734306 @default.
- W2886547942 creator A5036557948 @default.
- W2886547942 creator A5050474855 @default.
- W2886547942 creator A5058701004 @default.
- W2886547942 creator A5068510059 @default.
- W2886547942 creator A5076701302 @default.
- W2886547942 date "2004-02-01" @default.
- W2886547942 modified "2023-09-24" @default.
- W2886547942 title "Growth Hormone Induces Low-Density Lipoprotein Clearance but not Bile Acid Synthesis in Humans" @default.
- W2886547942 hasPublicationYear "2004" @default.
- W2886547942 type Work @default.
- W2886547942 sameAs 2886547942 @default.
- W2886547942 citedByCount "0" @default.
- W2886547942 crossrefType "journal-article" @default.
- W2886547942 hasAuthorship W2886547942A5022507631 @default.
- W2886547942 hasAuthorship W2886547942A5030265747 @default.
- W2886547942 hasAuthorship W2886547942A5035490163 @default.
- W2886547942 hasAuthorship W2886547942A5035734306 @default.
- W2886547942 hasAuthorship W2886547942A5036557948 @default.
- W2886547942 hasAuthorship W2886547942A5050474855 @default.
- W2886547942 hasAuthorship W2886547942A5058701004 @default.
- W2886547942 hasAuthorship W2886547942A5068510059 @default.
- W2886547942 hasAuthorship W2886547942A5076701302 @default.
- W2886547942 hasConcept C126322002 @default.
- W2886547942 hasConcept C134018914 @default.
- W2886547942 hasConcept C170493617 @default.
- W2886547942 hasConcept C185592680 @default.
- W2886547942 hasConcept C24998067 @default.
- W2886547942 hasConcept C2778163477 @default.
- W2886547942 hasConcept C2778491484 @default.
- W2886547942 hasConcept C2779399885 @default.
- W2886547942 hasConcept C2779620165 @default.
- W2886547942 hasConcept C2780072125 @default.
- W2886547942 hasConcept C43554185 @default.
- W2886547942 hasConcept C62231903 @default.
- W2886547942 hasConcept C71315377 @default.
- W2886547942 hasConcept C71924100 @default.
- W2886547942 hasConcept C96942376 @default.
- W2886547942 hasConceptScore W2886547942C126322002 @default.
- W2886547942 hasConceptScore W2886547942C134018914 @default.
- W2886547942 hasConceptScore W2886547942C170493617 @default.
- W2886547942 hasConceptScore W2886547942C185592680 @default.
- W2886547942 hasConceptScore W2886547942C24998067 @default.
- W2886547942 hasConceptScore W2886547942C2778163477 @default.
- W2886547942 hasConceptScore W2886547942C2778491484 @default.
- W2886547942 hasConceptScore W2886547942C2779399885 @default.
- W2886547942 hasConceptScore W2886547942C2779620165 @default.
- W2886547942 hasConceptScore W2886547942C2780072125 @default.
- W2886547942 hasConceptScore W2886547942C43554185 @default.
- W2886547942 hasConceptScore W2886547942C62231903 @default.
- W2886547942 hasConceptScore W2886547942C71315377 @default.
- W2886547942 hasConceptScore W2886547942C71924100 @default.
- W2886547942 hasConceptScore W2886547942C96942376 @default.
- W2886547942 hasLocation W28865479421 @default.
- W2886547942 hasOpenAccess W2886547942 @default.
- W2886547942 hasPrimaryLocation W28865479421 @default.
- W2886547942 hasRelatedWork W1969474907 @default.
- W2886547942 hasRelatedWork W1969981440 @default.
- W2886547942 hasRelatedWork W1978061546 @default.
- W2886547942 hasRelatedWork W1994752890 @default.
- W2886547942 hasRelatedWork W2028877591 @default.
- W2886547942 hasRelatedWork W2045035360 @default.
- W2886547942 hasRelatedWork W2048020127 @default.
- W2886547942 hasRelatedWork W2067600421 @default.
- W2886547942 hasRelatedWork W2079681363 @default.
- W2886547942 hasRelatedWork W2080948511 @default.
- W2886547942 hasRelatedWork W2101816307 @default.
- W2886547942 hasRelatedWork W2117517864 @default.
- W2886547942 hasRelatedWork W2146966629 @default.
- W2886547942 hasRelatedWork W2148129543 @default.
- W2886547942 hasRelatedWork W2156184134 @default.
- W2886547942 hasRelatedWork W2400580841 @default.
- W2886547942 hasRelatedWork W2435682629 @default.
- W2886547942 hasRelatedWork W2885994265 @default.
- W2886547942 hasRelatedWork W3139856113 @default.
- W2886547942 hasRelatedWork W3151774724 @default.
- W2886547942 isParatext "false" @default.
- W2886547942 isRetracted "false" @default.
- W2886547942 magId "2886547942" @default.
- W2886547942 workType "article" @default.