FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886579074> ?p ?o ?g. }

• W2886579074 endingPage "117" @default.
• W2886579074 startingPage "112" @default.
• W2886579074 abstract "An ultrasensitive and selective light-scattering (LS) aptasensor for prostate specific antigen (PSA) was developed based on bifunctional DNA decorated gold nanoparticles (Au NPs) by use of target stimuli-responsive assembly. Both binding sequence poly adenine (poly(dA), Domain I) and the recognition sequence aptamer (Domain II) of bifunctional ssDNA were in favor of the sensitivity for the fabricated light-scattering aptasensor due to modulated the lateral spacing of DNA on Au NPs surface and possessed strong antigen binding affinity, respectively. And they efficiently promoted the Au NPs aggregation and activated the signal of light-scattering of aptasensor. The formation of aptamer-PSA complex induced conformational transformation of the aptamer on the surface of the Au NPs-based aptasensor and then tuned the interparticle distance of gold nanoparticle assemblies. The larger scattering particles, the higher light-scattering intensity. Target stimuli-responsive aggregation behavior of Au NPs lit up the light-scattering signal of aptasensor. As the concentration of PSA increased, the light-scattering intensity gradually enhanced. The aptasensor response for PSA detection was in the linear range from 0.01 ng/mL to 20 ng/mL with the detection limit of 2 pg/mL. The thiol-free Au NPs-based light-scattering aptasensor has exceptional performances with ultrasensitivity and high selectivity besides the advantage of economic and facile fabrication. Moreover, the proposed target-activated aptasensor was applied for the detection of PSA in serum samples and demonstrated great potential in clinical applications." @default.
• W2886579074 created "2018-08-22" @default.
• W2886579074 creator A5017867375 @default.
• W2886579074 creator A5019686402 @default.
• W2886579074 creator A5038049470 @default.
• W2886579074 creator A5088281639 @default.
• W2886579074 date "2019-01-01" @default.
• W2886579074 modified "2023-10-16" @default.
• W2886579074 title "Target-activatable gold nanoparticle-based aptasensing for protein biomarkers using stimuli-responsive aggregation" @default.
• W2886579074 cites W1565276921 @default.
• W2886579074 cites W1830767646 @default.
• W2886579074 cites W1969159561 @default.
• W2886579074 cites W1973837500 @default.
• W2886579074 cites W2002337391 @default.
• W2886579074 cites W2006475060 @default.
• W2886579074 cites W2012776400 @default.
• W2886579074 cites W2023522763 @default.
• W2886579074 cites W2029932108 @default.
• W2886579074 cites W2033981868 @default.
• W2886579074 cites W2037988112 @default.
• W2886579074 cites W2049931703 @default.
• W2886579074 cites W2050073693 @default.
• W2886579074 cites W2055124682 @default.
• W2886579074 cites W2058163851 @default.
• W2886579074 cites W2068887262 @default.
• W2886579074 cites W2071416073 @default.
• W2886579074 cites W2077779605 @default.
• W2886579074 cites W2079321730 @default.
• W2886579074 cites W2085558639 @default.
• W2886579074 cites W2097571454 @default.
• W2886579074 cites W2104525153 @default.
• W2886579074 cites W2108309679 @default.
• W2886579074 cites W2110675408 @default.
• W2886579074 cites W2131091858 @default.
• W2886579074 cites W2135009695 @default.
• W2886579074 cites W2235954515 @default.
• W2886579074 cites W2274832362 @default.
• W2886579074 cites W2319756004 @default.
• W2886579074 cites W2507694613 @default.
• W2886579074 cites W2560447057 @default.
• W2886579074 cites W277895049 @default.
• W2886579074 cites W2781525129 @default.
• W2886579074 doi "https://doi.org/10.1016/j.talanta.2018.08.034" @default.
• W2886579074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30348365" @default.
• W2886579074 hasPublicationYear "2019" @default.
• W2886579074 type Work @default.
• W2886579074 sameAs 2886579074 @default.
• W2886579074 citedByCount "9" @default.
• W2886579074 countsByYear W28865790742019 @default.
• W2886579074 countsByYear W28865790742020 @default.
• W2886579074 countsByYear W28865790742021 @default.
• W2886579074 crossrefType "journal-article" @default.
• W2886579074 hasAuthorship W2886579074A5017867375 @default.
• W2886579074 hasAuthorship W2886579074A5019686402 @default.
• W2886579074 hasAuthorship W2886579074A5038049470 @default.
• W2886579074 hasAuthorship W2886579074A5088281639 @default.
• W2886579074 hasConcept C104819515 @default.
• W2886579074 hasConcept C119128265 @default.
• W2886579074 hasConcept C120456961 @default.
• W2886579074 hasConcept C120665830 @default.
• W2886579074 hasConcept C121332964 @default.
• W2886579074 hasConcept C128972844 @default.
• W2886579074 hasConcept C14631669 @default.
• W2886579074 hasConcept C153911025 @default.
• W2886579074 hasConcept C155672457 @default.
• W2886579074 hasConcept C161790260 @default.
• W2886579074 hasConcept C171250308 @default.
• W2886579074 hasConcept C185592680 @default.
• W2886579074 hasConcept C191486275 @default.
• W2886579074 hasConcept C192562407 @default.
• W2886579074 hasConcept C2780443040 @default.
• W2886579074 hasConcept C43617362 @default.
• W2886579074 hasConcept C55493867 @default.
• W2886579074 hasConcept C86803240 @default.
• W2886579074 hasConceptScore W2886579074C104819515 @default.
• W2886579074 hasConceptScore W2886579074C119128265 @default.
• W2886579074 hasConceptScore W2886579074C120456961 @default.
• W2886579074 hasConceptScore W2886579074C120665830 @default.
• W2886579074 hasConceptScore W2886579074C121332964 @default.
• W2886579074 hasConceptScore W2886579074C128972844 @default.
• W2886579074 hasConceptScore W2886579074C14631669 @default.
• W2886579074 hasConceptScore W2886579074C153911025 @default.
• W2886579074 hasConceptScore W2886579074C155672457 @default.
• W2886579074 hasConceptScore W2886579074C161790260 @default.
• W2886579074 hasConceptScore W2886579074C171250308 @default.
• W2886579074 hasConceptScore W2886579074C185592680 @default.
• W2886579074 hasConceptScore W2886579074C191486275 @default.
• W2886579074 hasConceptScore W2886579074C192562407 @default.
• W2886579074 hasConceptScore W2886579074C2780443040 @default.
• W2886579074 hasConceptScore W2886579074C43617362 @default.
• W2886579074 hasConceptScore W2886579074C55493867 @default.
• W2886579074 hasConceptScore W2886579074C86803240 @default.
• W2886579074 hasFunder F4320321001 @default.
• W2886579074 hasFunder F4320322769 @default.
• W2886579074 hasLocation W28865790741 @default.
• W2886579074 hasLocation W28865790742 @default.
• W2886579074 hasOpenAccess W2886579074 @default.
• W2886579074 hasPrimaryLocation W28865790741 @default.

• next