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- W2886588496 abstract "Currently, there is lack of standardized conditions for the collection and analysis of e-cigarette (EC) aerosol. Considering the urgent need for the development of these guidelines, a procedure for EC aerosol analysis was developed. A novel automatic e-cigarette aerosol generator was designed. For the first time, melt-blown non-woven fabric was applied for the effective uptake of compounds released from vaporized e-liquid. The extraction procedure was optimized in terms of type of extraction solvent, amount of sorbent and solvent volume. For optimization, a model e-liquid containing flavour additives belonging to various chemicals group with various chemical properties was investigated. The aerosol trapping efficiency was satisfactory and was equal to 92 ± 7%. Final determination was performed by GC-MS/MS. Quantitation was based on the mass change tracking approach (MCT), which assumes the monitoring of e-liquid mass changes before and after vaping. The combination of non-woven fabric and sampling approach (MCT) was proven to be effective in acquisition of reliable data. Thus, the concentrations in aerosol and emission factors were calculated for aerosols collected during the vaping of both model e-liquids and real samples. Validation was performed by evaluating key analytical parameters, such as linearity, accuracy, precision, limit of detection (LOD) and quantitation (LOQ). For all investigated compounds, recoveries from 70% to 118% together with precision and reproducibility below 12% were achieved. The applicability of the described approach was examined by analysing EC refill solutions commercially available on the Polish market." @default.
- W2886588496 created "2018-08-22" @default.
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- W2886588496 date "2018-12-01" @default.
- W2886588496 modified "2023-10-18" @default.
- W2886588496 title "New approach for e-cigarette aerosol collection by an original automatic aerosol generator utilizing melt-blown non-woven fabric" @default.
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- W2886588496 doi "https://doi.org/10.1016/j.aca.2018.08.015" @default.
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