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- W2886606550 endingPage "56" @default.
- W2886606550 startingPage "46" @default.
- W2886606550 abstract "The stem cells make the backbone of repair system in an individual, which is attributed to their special characteristic features like self-renewal, multiplication, homing, immuno-modulation and plasticity. Due to the limited control over the cellular processes, variability in results and small number of controlled clinical trials stem cell applications currently remain limited, however their potential and applicability in biological research and therapy cannot be overemphasized. Among various stem cell types, mesenchymal stem cells (MSCs) are extensively studied for clinical applications owing to their readily available sources, easy harvesting and culturing, and their ability to differentiate into numerous tissue cells, besides, minimal teratogenic potential. Sheep is one of the commonly used large animal models for humans. Sheep MSCs have been isolated, culture expanded and characterized similar to that of humans and utilized in various translational models for human medical applications. The current review throws light on sheep mesenchymal stem cell sources, characterization and potential therapeutic applications in perspective of human medicine. The information summarized in the manuscript has been taken mainly from authentic sources." @default.
- W2886606550 created "2018-08-22" @default.
- W2886606550 creator A5042967561 @default.
- W2886606550 creator A5065472431 @default.
- W2886606550 date "2018-12-01" @default.
- W2886606550 modified "2023-09-25" @default.
- W2886606550 title "Mesenchymal stem cell research in sheep: Current status and future prospects" @default.
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