FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886638820> ?p ?o ?g. }

• W2886638820 abstract "The marine polychaete annelid Platynereis dumerilii has recently emerged as a prominent organism for the study of development, evolution, stem cells, regeneration, marine ecology, chronobiology and neurobiology within metazoans. Its phylogenetic position within the spiralian/ lophotrochozoan clade, the comparatively high conservation of ancestral features in the Platynereis genome, and experimental access to any stage within its life cycle, make Platynereis an important model for elucidating the complex regulatory and functional molecular mechanisms governing early development, later organogenesis, and various features of its larval and adult life. High resolution RNA-seq gene expression data obtained from specific developmental stages can be used to dissect early developmental mechanisms. However, the potential for discovery of these mechanisms relies on tools to search, retrieve, and compare genome-wide information within Platynereis, and across other metazoan taxa. To facilitate exploration and discovery by the broader scientific community, we have developed a web-based, searchable online research tool, PdumBase, featuring the first comprehensive transcriptome database for Platynereis dumerilii during early stages of development (2 h ~ 14 h). Our database also includes additional stages over the P. dumerilii life cycle and provides access to the expression data of 17,213 genes (31,806 transcripts) along with annotation information sourced from Swiss-Prot, Gene Ontology, KEGG pathways, Pfam domains, TmHMM, SingleP, and EggNOG orthology. Expression data for each gene includes the stage, the normalized FPKM, the raw read counts, and information that can be leveraged for statistical analyses of differential gene expression and the construction of genome-wide co-expression networks. In addition, PdumBase offers early stage transcriptome expression data from five further species as a valuable resource for investigators interested in comparing early development in different organisms. To understand conservation of Platynereis gene models and to validate gene annotation, most Platynereis gene models include a comprehensive phylogenetic analysis across 18 species representing diverse metazoan taxa. PdumBase represents the first online resource for the early developmental transcriptome of Platynereis dumerilii. It serves as a research platform for discovery and exploration of gene expression during early stages, throughout the Platynereis life cycle, and enables comparison to other model organisms. PdumBase is freely available at http://pdumbase.gdcb.iastate.edu ." @default.
• W2886638820 created "2018-08-22" @default.
• W2886638820 creator A5059335002 @default.
• W2886638820 creator A5071625660 @default.
• W2886638820 creator A5081407228 @default.
• W2886638820 creator A5050556560 @default.
• W2886638820 date "2018-08-16" @default.
• W2886638820 modified "2023-10-12" @default.
• W2886638820 title "PdumBase: a transcriptome database and research tool for Platynereis dumerilii and early development of other metazoans" @default.
• W2886638820 cites W142231902 @default.
• W2886638820 cites W1515226261 @default.
• W2886638820 cites W1519616493 @default.
• W2886638820 cites W1584332859 @default.
• W2886638820 cites W1615515432 @default.
• W2886638820 cites W1855805349 @default.
• W2886638820 cites W1966327575 @default.
• W2886638820 cites W1976667743 @default.
• W2886638820 cites W1977544680 @default.
• W2886638820 cites W1977865827 @default.
• W2886638820 cites W1984191157 @default.
• W2886638820 cites W1985740972 @default.
• W2886638820 cites W1992485257 @default.
• W2886638820 cites W1993273604 @default.
• W2886638820 cites W1994977528 @default.
• W2886638820 cites W1999574084 @default.
• W2886638820 cites W2008856488 @default.
• W2886638820 cites W2011657487 @default.
• W2886638820 cites W2013264450 @default.
• W2886638820 cites W2015121260 @default.
• W2886638820 cites W2020493683 @default.
• W2886638820 cites W2020766301 @default.
• W2886638820 cites W2024531262 @default.
• W2886638820 cites W2026345779 @default.
• W2886638820 cites W2036897871 @default.
• W2886638820 cites W2037216703 @default.
• W2886638820 cites W2039531605 @default.
• W2886638820 cites W2042494430 @default.
• W2886638820 cites W2052064799 @default.
• W2886638820 cites W2059688577 @default.
• W2886638820 cites W2067804517 @default.
• W2886638820 cites W2068773723 @default.
• W2886638820 cites W2070296164 @default.
• W2886638820 cites W2077486976 @default.
• W2886638820 cites W2078125486 @default.
• W2886638820 cites W2088487900 @default.
• W2886638820 cites W2091129492 @default.
• W2886638820 cites W2094201044 @default.
• W2886638820 cites W2094217838 @default.
• W2886638820 cites W2097065948 @default.
• W2886638820 cites W2098218231 @default.
• W2886638820 cites W2103568115 @default.
• W2886638820 cites W2114104545 @default.
• W2886638820 cites W2115714014 @default.
• W2886638820 cites W2118522801 @default.
• W2886638820 cites W2118930999 @default.
• W2886638820 cites W2119034410 @default.
• W2886638820 cites W2120457919 @default.
• W2886638820 cites W2121449726 @default.
• W2886638820 cites W2124985265 @default.
• W2886638820 cites W2129924706 @default.
• W2886638820 cites W2131271579 @default.
• W2886638820 cites W2134436946 @default.
• W2886638820 cites W2135435176 @default.
• W2886638820 cites W2139431434 @default.
• W2886638820 cites W2141052558 @default.
• W2886638820 cites W2146217341 @default.
• W2886638820 cites W2152556446 @default.
• W2886638820 cites W2152770371 @default.
• W2886638820 cites W2152973976 @default.
• W2886638820 cites W2153416949 @default.
• W2886638820 cites W2158050409 @default.
• W2886638820 cites W2165467455 @default.
• W2886638820 cites W2201927605 @default.
• W2886638820 cites W2233936681 @default.
• W2886638820 cites W2263582186 @default.
• W2886638820 cites W2283570988 @default.
• W2886638820 cites W2341388571 @default.
• W2886638820 cites W2480717326 @default.
• W2886638820 cites W2481000200 @default.
• W2886638820 cites W2498420844 @default.
• W2886638820 cites W2624543065 @default.
• W2886638820 cites W2771649768 @default.
• W2886638820 cites W2785647182 @default.
• W2886638820 cites W4210767115 @default.
• W2886638820 cites W4233107515 @default.
• W2886638820 cites W4241844843 @default.
• W2886638820 doi "https://doi.org/10.1186/s12864-018-4987-0" @default.
• W2886638820 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6097317" @default.
• W2886638820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30115014" @default.
• W2886638820 hasPublicationYear "2018" @default.
• W2886638820 type Work @default.
• W2886638820 sameAs 2886638820 @default.
• W2886638820 citedByCount "16" @default.
• W2886638820 countsByYear W28866388202019 @default.
• W2886638820 countsByYear W28866388202020 @default.
• W2886638820 countsByYear W28866388202021 @default.
• W2886638820 countsByYear W28866388202022 @default.
• W2886638820 countsByYear W28866388202023 @default.
• W2886638820 crossrefType "journal-article" @default.
• W2886638820 hasAuthorship W2886638820A5050556560 @default.

• next