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- W2886641522 abstract "Alternative splicing of RNA is a fundamental post-transcriptional regulatory process that leads to a vast diversity of proteins being translated from a relatively small number of genomic loci. Microexons, a set of very small protein-coding sequences of 1-17 amino acids, have only recently been recognised as an important part of pre-mRNA processing. Recent studies have revealed that microexons can play important roles in various cellular functions, protein-protein interactions and have also been associated with various neurological diseases. This review provides an update on research covering the functional impact of microexons on the biology of a cell and disease, and the mechanisms by which their splicing is regulated. Finally, the current bioinformatics methods for detecting microexons are discussed." @default.
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- W2886641522 date "2018-01-01" @default.
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- W2886641522 title "Microexons: novel regulators of the transcriptome" @default.
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- W2886641522 doi "https://doi.org/10.1080/23324015.2018.1491940" @default.
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