FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886725778> ?p ?o ?g. }

• W2886725778 endingPage "1224" @default.
• W2886725778 startingPage "1224" @default.
• W2886725778 abstract "Statin medications are widely prescribed for cardiovascular risk reduction. Myalgia and rhabdomyolysis are well-recognized adverse effects of statins, and they resolve with the cessation of statin therapy. Idiopathic inflammatory myositis (IIM) is a heterogeneous group of autoimmune myopathies that may also be associated with statin use. Recently, statin-associated autoimmune myopathy has been recognized as a distinct entity with the presence of specific autoantibodies against hydroxymethylglutaryl-coenzyme A reductase, which results in a necrotizing myositis that does not resolve with cessation of statin therapy and requires treatment with immunosuppressive agents.To examine the association between histologically confirmed IIM and current exposure to statin medications.Population-based case-control study using the South Australian Myositis Database of all histologically confirmed cases of IIM diagnosed between 1990 and 2014 in patients 40 years or older (n = 221) and population-based controls from the North West Adelaide Health Study (n = 662), matched by age and sex in a 3:1 ratio of controls to cases. Data analysis using conditional logistic regression was performed from June 1, 2016, to July 14, 2017.Current statin medication use.Unadjusted and adjusted (for diabetes and cardiovascular disease) odds ratios and 95% CIs for likelihood of inflammatory myositis.A total of 221 IIM cases met the inclusion criteria with a mean (SD) age of 62.2 (10.8) years, and 132 (59.7%) were female. Statin exposure at the time of IIM diagnosis was 68 of 221 patients (30.8%) and 142 of 662 matched controls (21.5%) (P = .005). There was an almost 2-fold increased likelihood of statin exposure in patients with IIM compared with controls (adjusted odds ratio, 1.79; 95% CI, 1.23-2.60; P = .001). Similar results were observed when patients with necrotizing myositis were excluded from the analysis (adjusted odds ratio, 1.92; 95% CI, 1.29-2.86; P = .001).In this large population-based study, statin exposure was significantly associated with histologically confirmed IIM. Given the increased use of statins worldwide and the severity of IIM, increased awareness and recognition of this potentially rare adverse effect of statin exposure is needed." @default.
• W2886725778 created "2018-08-22" @default.
• W2886725778 creator A5026779492 @default.
• W2886725778 creator A5028899651 @default.
• W2886725778 creator A5034392329 @default.
• W2886725778 creator A5038811933 @default.
• W2886725778 creator A5049674178 @default.
• W2886725778 creator A5057456571 @default.
• W2886725778 creator A5060810729 @default.
• W2886725778 date "2018-09-01" @default.
• W2886725778 modified "2023-09-26" @default.
• W2886725778 title "Association of Statin Exposure With Histologically Confirmed Idiopathic Inflammatory Myositis in an Australian Population" @default.
• W2886725778 cites W1656822188 @default.
• W2886725778 cites W1927105467 @default.
• W2886725778 cites W1941444657 @default.
• W2886725778 cites W1982857093 @default.
• W2886725778 cites W1990763296 @default.
• W2886725778 cites W1998672288 @default.
• W2886725778 cites W2026362028 @default.
• W2886725778 cites W2095281951 @default.
• W2886725778 cites W2106859384 @default.
• W2886725778 cites W2118184073 @default.
• W2886725778 cites W2129295404 @default.
• W2886725778 cites W2131124395 @default.
• W2886725778 cites W2134159541 @default.
• W2886725778 cites W2144742353 @default.
• W2886725778 cites W2159985097 @default.
• W2886725778 cites W2335358665 @default.
• W2886725778 cites W2413538055 @default.
• W2886725778 cites W2474756647 @default.
• W2886725778 cites W2535158955 @default.
• W2886725778 cites W2584900874 @default.
• W2886725778 cites W2588194851 @default.
• W2886725778 cites W2591966673 @default.
• W2886725778 cites W2752172579 @default.
• W2886725778 cites W2782380257 @default.
• W2886725778 cites W4230286948 @default.
• W2886725778 cites W4238881450 @default.
• W2886725778 cites W4245211460 @default.
• W2886725778 doi "https://doi.org/10.1001/jamainternmed.2018.2859" @default.
• W2886725778 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6142971" @default.
• W2886725778 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30073275" @default.
• W2886725778 hasPublicationYear "2018" @default.
• W2886725778 type Work @default.
• W2886725778 sameAs 2886725778 @default.
• W2886725778 citedByCount "14" @default.
• W2886725778 countsByYear W28867257782018 @default.
• W2886725778 countsByYear W28867257782019 @default.
• W2886725778 countsByYear W28867257782020 @default.
• W2886725778 countsByYear W28867257782021 @default.
• W2886725778 countsByYear W28867257782022 @default.
• W2886725778 countsByYear W28867257782023 @default.
• W2886725778 crossrefType "journal-article" @default.
• W2886725778 hasAuthorship W2886725778A5026779492 @default.
• W2886725778 hasAuthorship W2886725778A5028899651 @default.
• W2886725778 hasAuthorship W2886725778A5034392329 @default.
• W2886725778 hasAuthorship W2886725778A5038811933 @default.
• W2886725778 hasAuthorship W2886725778A5049674178 @default.
• W2886725778 hasAuthorship W2886725778A5057456571 @default.
• W2886725778 hasAuthorship W2886725778A5060810729 @default.
• W2886725778 hasBestOaLocation W28867257781 @default.
• W2886725778 hasConcept C126322002 @default.
• W2886725778 hasConcept C156957248 @default.
• W2886725778 hasConcept C2776839432 @default.
• W2886725778 hasConcept C2777300911 @default.
• W2886725778 hasConcept C2778616394 @default.
• W2886725778 hasConcept C2778751314 @default.
• W2886725778 hasConcept C2780181341 @default.
• W2886725778 hasConcept C2781232998 @default.
• W2886725778 hasConcept C2908647359 @default.
• W2886725778 hasConcept C71924100 @default.
• W2886725778 hasConcept C99454951 @default.
• W2886725778 hasConceptScore W2886725778C126322002 @default.
• W2886725778 hasConceptScore W2886725778C156957248 @default.
• W2886725778 hasConceptScore W2886725778C2776839432 @default.
• W2886725778 hasConceptScore W2886725778C2777300911 @default.
• W2886725778 hasConceptScore W2886725778C2778616394 @default.
• W2886725778 hasConceptScore W2886725778C2778751314 @default.
• W2886725778 hasConceptScore W2886725778C2780181341 @default.
• W2886725778 hasConceptScore W2886725778C2781232998 @default.
• W2886725778 hasConceptScore W2886725778C2908647359 @default.
• W2886725778 hasConceptScore W2886725778C71924100 @default.
• W2886725778 hasConceptScore W2886725778C99454951 @default.
• W2886725778 hasIssue "9" @default.
• W2886725778 hasLocation W28867257781 @default.
• W2886725778 hasLocation W28867257782 @default.
• W2886725778 hasLocation W28867257783 @default.
• W2886725778 hasLocation W28867257784 @default.
• W2886725778 hasOpenAccess W2886725778 @default.
• W2886725778 hasPrimaryLocation W28867257781 @default.
• W2886725778 hasRelatedWork W1519754357 @default.
• W2886725778 hasRelatedWork W152423387 @default.
• W2886725778 hasRelatedWork W1967436487 @default.
• W2886725778 hasRelatedWork W2041747153 @default.
• W2886725778 hasRelatedWork W2081725117 @default.
• W2886725778 hasRelatedWork W2082658142 @default.
• W2886725778 hasRelatedWork W2163226208 @default.
• W2886725778 hasRelatedWork W2791516976 @default.

• next