FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886733748> ?p ?o ?g. }

• W2886733748 endingPage "94" @default.
• W2886733748 startingPage "87" @default.
• W2886733748 abstract "Gene expression can vary with the organisms' life stage. It is known that embryos can be more sensitive to toxicant exposure, as previously demonstrated for Enchytraeus crypticus (Oligochaeta) exposed to cadmium (Cd), known to cause embryotoxicity and hatching delay. It was shown that Ca enters embryos via the L-type Ca channels in the cocoon membrane, this being affected in Cd exposed embryos (Cd-Ca competition is well-known). In the present study, the embryotoxic mechanisms of Cd were studied via high-throughput gene expression for E. crypticus. Cocoons (1–2 days old), instead of the adult organism, were exposed in Cd spiked LUFA 2.2 soil during 1 day. Results showed that Cd affected Ca homeostasis which is implicated in several other molecular processes. Several of the major modulators of Cd toxicity (e.g., impaired gene expression, cell cycle arrest, DNA and mitochondrial damage) were identified in the embryos showing its relevancy as a model in ecotoxicogenomics. The draft Adverse Outcome Pathway was improved. Previously was hypothesized that gene regulation mechanisms were activated to synthesize more Ca channel proteins – this was confirmed here. Further, novel evidences were that, besides the extracellular competition, Cd competes intracellularly which causes a reduction in Ca efflux, and potentiates Cd embryotoxicity." @default.
• W2886733748 created "2018-08-22" @default.
• W2886733748 creator A5012338403 @default.
• W2886733748 creator A5025045559 @default.
• W2886733748 creator A5038264749 @default.
• W2886733748 creator A5049064929 @default.
• W2886733748 creator A5057494400 @default.
• W2886733748 creator A5067511868 @default.
• W2886733748 creator A5073053565 @default.
• W2886733748 date "2018-12-01" @default.
• W2886733748 modified "2023-10-17" @default.
• W2886733748 title "High-throughput gene expression in soil invertebrate embryos – Mechanisms of Cd toxicity in Enchytraeus crypticus" @default.
• W2886733748 cites W1021055550 @default.
• W2886733748 cites W1154801988 @default.
• W2886733748 cites W1539347645 @default.
• W2886733748 cites W1969839746 @default.
• W2886733748 cites W1973094248 @default.
• W2886733748 cites W1975308921 @default.
• W2886733748 cites W1976750784 @default.
• W2886733748 cites W1977446960 @default.
• W2886733748 cites W1997625069 @default.
• W2886733748 cites W2005088664 @default.
• W2886733748 cites W2010559105 @default.
• W2886733748 cites W2014949802 @default.
• W2886733748 cites W2023386681 @default.
• W2886733748 cites W2032402762 @default.
• W2886733748 cites W2032733245 @default.
• W2886733748 cites W2033285747 @default.
• W2886733748 cites W2033456272 @default.
• W2886733748 cites W2034298458 @default.
• W2886733748 cites W2034340505 @default.
• W2886733748 cites W2038364461 @default.
• W2886733748 cites W2040379983 @default.
• W2886733748 cites W2041824090 @default.
• W2886733748 cites W2059363305 @default.
• W2886733748 cites W2064297857 @default.
• W2886733748 cites W2079993886 @default.
• W2886733748 cites W2083217788 @default.
• W2886733748 cites W2086365013 @default.
• W2886733748 cites W2088853004 @default.
• W2886733748 cites W2094991879 @default.
• W2886733748 cites W2100413928 @default.
• W2886733748 cites W2103805605 @default.
• W2886733748 cites W2110256992 @default.
• W2886733748 cites W2120024428 @default.
• W2886733748 cites W2125349610 @default.
• W2886733748 cites W2133579817 @default.
• W2886733748 cites W2146462638 @default.
• W2886733748 cites W2146512944 @default.
• W2886733748 cites W2160873790 @default.
• W2886733748 cites W2162681898 @default.
• W2886733748 cites W2261749906 @default.
• W2886733748 cites W2589981917 @default.
• W2886733748 cites W2594694314 @default.
• W2886733748 cites W2791878075 @default.
• W2886733748 doi "https://doi.org/10.1016/j.chemosphere.2018.08.068" @default.
• W2886733748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30142569" @default.
• W2886733748 hasPublicationYear "2018" @default.
• W2886733748 type Work @default.
• W2886733748 sameAs 2886733748 @default.
• W2886733748 citedByCount "17" @default.
• W2886733748 countsByYear W28867337482019 @default.
• W2886733748 countsByYear W28867337482020 @default.
• W2886733748 countsByYear W28867337482021 @default.
• W2886733748 countsByYear W28867337482022 @default.
• W2886733748 countsByYear W28867337482023 @default.
• W2886733748 crossrefType "journal-article" @default.
• W2886733748 hasAuthorship W2886733748A5012338403 @default.
• W2886733748 hasAuthorship W2886733748A5025045559 @default.
• W2886733748 hasAuthorship W2886733748A5038264749 @default.
• W2886733748 hasAuthorship W2886733748A5049064929 @default.
• W2886733748 hasAuthorship W2886733748A5057494400 @default.
• W2886733748 hasAuthorship W2886733748A5067511868 @default.
• W2886733748 hasAuthorship W2886733748A5073053565 @default.
• W2886733748 hasConcept C104317684 @default.
• W2886733748 hasConcept C150194340 @default.
• W2886733748 hasConcept C153911025 @default.
• W2886733748 hasConcept C16685009 @default.
• W2886733748 hasConcept C178790620 @default.
• W2886733748 hasConcept C185592680 @default.
• W2886733748 hasConcept C196843134 @default.
• W2886733748 hasConcept C2780473477 @default.
• W2886733748 hasConcept C28406088 @default.
• W2886733748 hasConcept C29730261 @default.
• W2886733748 hasConcept C54355233 @default.
• W2886733748 hasConcept C71924100 @default.
• W2886733748 hasConcept C86803240 @default.
• W2886733748 hasConcept C95444343 @default.
• W2886733748 hasConceptScore W2886733748C104317684 @default.
• W2886733748 hasConceptScore W2886733748C150194340 @default.
• W2886733748 hasConceptScore W2886733748C153911025 @default.
• W2886733748 hasConceptScore W2886733748C16685009 @default.
• W2886733748 hasConceptScore W2886733748C178790620 @default.
• W2886733748 hasConceptScore W2886733748C185592680 @default.
• W2886733748 hasConceptScore W2886733748C196843134 @default.
• W2886733748 hasConceptScore W2886733748C2780473477 @default.
• W2886733748 hasConceptScore W2886733748C28406088 @default.
• W2886733748 hasConceptScore W2886733748C29730261 @default.

• next