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• W2886743721 abstract "Objectives Anecdotal reports and preliminary studies suggest a therapeutic potential of cannabis in Tourette syndrome. We report the case of a female patient suffering from treatment-resistant Tourette syndrome. Methods Guideline-directed antipsychotic treatment with risperidone and aripiprazole as well as pure delta-9-tetrahydrocannabinol had no significant effect on Tourette syndrome symptomatology. Results Following administration of a daily dosage of 10 mg delta-9-tetrahydrocannabinol combined with 20 mg cannabidiol (CBD), the patient showed a rapid and highly significant improvement in the Yale Global Tic Severity Scale. Conclusions It can be speculated whether the beneficial effects may rely on the pharmacological properties of cannabidiol." @default.
• W2886743721 created "2018-08-22" @default.
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• W2886743721 date "2018-07-30" @default.
• W2886743721 modified "2023-09-26" @default.
• W2886743721 title "Pure delta-9-tetrahydrocannabinol and its combination with cannabidiol in treatment-resistant Tourette syndrome: A case report" @default.
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• W2886743721 doi "https://doi.org/10.1177/0091217418791455" @default.
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