Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886851948> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2886851948 abstract "Objective— An elevated free fatty acid (FFA) level impairs endothelium-dependent vasodilation in humans, which may be pathophysiologically relevant to the development of endothelial dysfunction in patients with insulin resistance. We investigated the effect of inhibition of the renin-angiotensin system (RAS) on FFA-induced endothelial dysfunction. Methods and Results— Changes in forearm blood flow during intra-arterial infusion of acetylcholine were measured by plethysmography before and after systemic infusion of lipid/heparin in 10 healthy subjects given a single dose of placebo, losartan (50 mg), or perindopril (8 mg). Endothelial function after lipid/heparin infusion was also investigated with the coinfusion of vitamin C or NG-monomethyl-l-arginine (L-NMMA). Elevated FFA significantly reduced the response to acetylcholine by 37.7% (P=0.0096) without L-NMMA, but not the response with L-NMMA, whereas FFA did not affect the response to nitroprusside. The single dose of either losartan or perindopril comp..." @default.
- W2886851948 created "2018-08-22" @default.
- W2886851948 creator A5031323210 @default.
- W2886851948 creator A5058272404 @default.
- W2886851948 creator A5065326452 @default.
- W2886851948 creator A5087538192 @default.
- W2886851948 creator A5091906473 @default.
- W2886851948 date "2005-11-01" @default.
- W2886851948 modified "2023-09-24" @default.
- W2886851948 title "Inhibition of the Renin-Angiotensin System Prevents Free Fatty Acid–Induced Acute Endothelial Dysfunction in Humans" @default.
- W2886851948 hasPublicationYear "2005" @default.
- W2886851948 type Work @default.
- W2886851948 sameAs 2886851948 @default.
- W2886851948 citedByCount "0" @default.
- W2886851948 crossrefType "journal-article" @default.
- W2886851948 hasAuthorship W2886851948A5031323210 @default.
- W2886851948 hasAuthorship W2886851948A5058272404 @default.
- W2886851948 hasAuthorship W2886851948A5065326452 @default.
- W2886851948 hasAuthorship W2886851948A5087538192 @default.
- W2886851948 hasAuthorship W2886851948A5091906473 @default.
- W2886851948 hasConcept C120770815 @default.
- W2886851948 hasConcept C126322002 @default.
- W2886851948 hasConcept C134018914 @default.
- W2886851948 hasConcept C198710026 @default.
- W2886851948 hasConcept C2775910092 @default.
- W2886851948 hasConcept C2776992346 @default.
- W2886851948 hasConcept C2779200603 @default.
- W2886851948 hasConcept C2780288358 @default.
- W2886851948 hasConcept C2780972559 @default.
- W2886851948 hasConcept C2908929049 @default.
- W2886851948 hasConcept C71924100 @default.
- W2886851948 hasConcept C84393581 @default.
- W2886851948 hasConcept C98274493 @default.
- W2886851948 hasConceptScore W2886851948C120770815 @default.
- W2886851948 hasConceptScore W2886851948C126322002 @default.
- W2886851948 hasConceptScore W2886851948C134018914 @default.
- W2886851948 hasConceptScore W2886851948C198710026 @default.
- W2886851948 hasConceptScore W2886851948C2775910092 @default.
- W2886851948 hasConceptScore W2886851948C2776992346 @default.
- W2886851948 hasConceptScore W2886851948C2779200603 @default.
- W2886851948 hasConceptScore W2886851948C2780288358 @default.
- W2886851948 hasConceptScore W2886851948C2780972559 @default.
- W2886851948 hasConceptScore W2886851948C2908929049 @default.
- W2886851948 hasConceptScore W2886851948C71924100 @default.
- W2886851948 hasConceptScore W2886851948C84393581 @default.
- W2886851948 hasConceptScore W2886851948C98274493 @default.
- W2886851948 hasLocation W28868519481 @default.
- W2886851948 hasOpenAccess W2886851948 @default.
- W2886851948 hasPrimaryLocation W28868519481 @default.
- W2886851948 hasRelatedWork W1599424352 @default.
- W2886851948 hasRelatedWork W1975746694 @default.
- W2886851948 hasRelatedWork W2002149579 @default.
- W2886851948 hasRelatedWork W2039237702 @default.
- W2886851948 hasRelatedWork W2042667554 @default.
- W2886851948 hasRelatedWork W2046770930 @default.
- W2886851948 hasRelatedWork W2050957687 @default.
- W2886851948 hasRelatedWork W2062988685 @default.
- W2886851948 hasRelatedWork W2072018173 @default.
- W2886851948 hasRelatedWork W2076279798 @default.
- W2886851948 hasRelatedWork W2081459207 @default.
- W2886851948 hasRelatedWork W2089125418 @default.
- W2886851948 hasRelatedWork W2126011998 @default.
- W2886851948 hasRelatedWork W2167643161 @default.
- W2886851948 hasRelatedWork W2370028848 @default.
- W2886851948 hasRelatedWork W2415887131 @default.
- W2886851948 hasRelatedWork W2774046602 @default.
- W2886851948 hasRelatedWork W2883579801 @default.
- W2886851948 hasRelatedWork W2886796570 @default.
- W2886851948 hasRelatedWork W3037536988 @default.
- W2886851948 isParatext "false" @default.
- W2886851948 isRetracted "false" @default.
- W2886851948 magId "2886851948" @default.
- W2886851948 workType "article" @default.