Matches in SemOpenAlex for { <https://semopenalex.org/work/W2886983313> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2886983313 endingPage "222" @default.
- W2886983313 startingPage "217" @default.
- W2886983313 abstract "Background The syndrome of constipation with other abdominal symptoms (“proximal constipation”) in ulcerative colitis (UC) is commonly recognized by practitioners but is poorly described, with no recognized definition and little understanding with regard to prevalence and effect of therapies on disease outcomes. This study aimed to address these issues in a cross‐sectional, consecutive series of patients with UC. Methods A working definition of proximal constipation was established. Consecutive patients were recruited, and their disease activity, recent medications, and investigations plus abdominal symptoms were assessed at a study visit. Relevant clinical data were also extracted from medical records. Results Of 125 patients with UC, (mean age 47, range 14–84 years, 61 male), 58 (46%) fulfilled the definition of proximal constipation. The main symptoms were reduced stool frequency (69%), hard stools (43%), abdominal pain (40%), excessive flatus (29%), straining (24%), and sensation of incomplete emptying (14%). Proximal constipation was associated with female gender (OR 3.45 [1.45–8.24]), left‐sided (OR 2.84 [1.14–7.11]) and concurrently active disease (OR 5.56 [1.96–16.67]), but not age, disease duration or therapy. A total of 88% had an increase in anti‐inflammatory therapy, with the use of laxatives or fiber supplements in 63% compared with 1.4% of those without proximal constipation. Conclusions Proximal constipation is common, and its risk increases in active and distal disease, especially in women. Validation of its definition and evaluation of therapeutic strategies are needed. A new term “ulcerative colitis‐associated constipation syndrome” is proposed to more accurately depict its nature." @default.
- W2886983313 created "2018-08-22" @default.
- W2886983313 creator A5015260170 @default.
- W2886983313 creator A5020925830 @default.
- W2886983313 creator A5034931964 @default.
- W2886983313 creator A5041799453 @default.
- W2886983313 date "2018-08-05" @default.
- W2886983313 modified "2023-10-05" @default.
- W2886983313 title "Characterization of ulcerative colitis-associated constipation syndrome (proximal constipation)" @default.
- W2886983313 cites W1627613865 @default.
- W2886983313 cites W1660899365 @default.
- W2886983313 cites W1983106427 @default.
- W2886983313 cites W2037001083 @default.
- W2886983313 cites W2042271381 @default.
- W2886983313 cites W2059142969 @default.
- W2886983313 cites W2069885209 @default.
- W2886983313 cites W2070667274 @default.
- W2886983313 cites W2075398278 @default.
- W2886983313 cites W2079666478 @default.
- W2886983313 cites W2093671789 @default.
- W2886983313 cites W2094318583 @default.
- W2886983313 cites W2098254123 @default.
- W2886983313 cites W2113050165 @default.
- W2886983313 cites W2142940830 @default.
- W2886983313 cites W2143435653 @default.
- W2886983313 cites W2145135012 @default.
- W2886983313 cites W2162278126 @default.
- W2886983313 cites W2166386674 @default.
- W2886983313 cites W2166930089 @default.
- W2886983313 cites W2188248802 @default.
- W2886983313 doi "https://doi.org/10.1002/jgh3.12076" @default.
- W2886983313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6207018" @default.
- W2886983313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30483593" @default.
- W2886983313 hasPublicationYear "2018" @default.
- W2886983313 type Work @default.
- W2886983313 sameAs 2886983313 @default.
- W2886983313 citedByCount "9" @default.
- W2886983313 countsByYear W28869833132019 @default.
- W2886983313 countsByYear W28869833132020 @default.
- W2886983313 countsByYear W28869833132021 @default.
- W2886983313 countsByYear W28869833132022 @default.
- W2886983313 countsByYear W28869833132023 @default.
- W2886983313 crossrefType "journal-article" @default.
- W2886983313 hasAuthorship W2886983313A5015260170 @default.
- W2886983313 hasAuthorship W2886983313A5020925830 @default.
- W2886983313 hasAuthorship W2886983313A5034931964 @default.
- W2886983313 hasAuthorship W2886983313A5041799453 @default.
- W2886983313 hasBestOaLocation W28869833131 @default.
- W2886983313 hasConcept C108797546 @default.
- W2886983313 hasConcept C126322002 @default.
- W2886983313 hasConcept C195910791 @default.
- W2886983313 hasConcept C2778260677 @default.
- W2886983313 hasConcept C2778271842 @default.
- W2886983313 hasConcept C2779134260 @default.
- W2886983313 hasConcept C2779642851 @default.
- W2886983313 hasConcept C2780479503 @default.
- W2886983313 hasConcept C2780955771 @default.
- W2886983313 hasConcept C2781112942 @default.
- W2886983313 hasConcept C71924100 @default.
- W2886983313 hasConcept C90924648 @default.
- W2886983313 hasConceptScore W2886983313C108797546 @default.
- W2886983313 hasConceptScore W2886983313C126322002 @default.
- W2886983313 hasConceptScore W2886983313C195910791 @default.
- W2886983313 hasConceptScore W2886983313C2778260677 @default.
- W2886983313 hasConceptScore W2886983313C2778271842 @default.
- W2886983313 hasConceptScore W2886983313C2779134260 @default.
- W2886983313 hasConceptScore W2886983313C2779642851 @default.
- W2886983313 hasConceptScore W2886983313C2780479503 @default.
- W2886983313 hasConceptScore W2886983313C2780955771 @default.
- W2886983313 hasConceptScore W2886983313C2781112942 @default.
- W2886983313 hasConceptScore W2886983313C71924100 @default.
- W2886983313 hasConceptScore W2886983313C90924648 @default.
- W2886983313 hasIssue "5" @default.
- W2886983313 hasLocation W28869833131 @default.
- W2886983313 hasLocation W28869833132 @default.
- W2886983313 hasLocation W28869833133 @default.
- W2886983313 hasLocation W28869833134 @default.
- W2886983313 hasLocation W28869833135 @default.
- W2886983313 hasOpenAccess W2886983313 @default.
- W2886983313 hasPrimaryLocation W28869833131 @default.
- W2886983313 hasRelatedWork W130502936 @default.
- W2886983313 hasRelatedWork W1993434123 @default.
- W2886983313 hasRelatedWork W2086642698 @default.
- W2886983313 hasRelatedWork W2147533789 @default.
- W2886983313 hasRelatedWork W2606289477 @default.
- W2886983313 hasRelatedWork W3014412551 @default.
- W2886983313 hasRelatedWork W3201138048 @default.
- W2886983313 hasRelatedWork W4239951552 @default.
- W2886983313 hasRelatedWork W4256455251 @default.
- W2886983313 hasRelatedWork W4386221107 @default.
- W2886983313 hasVolume "2" @default.
- W2886983313 isParatext "false" @default.
- W2886983313 isRetracted "false" @default.
- W2886983313 magId "2886983313" @default.
- W2886983313 workType "article" @default.