FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887012907> ?p ?o ?g. }

• W2887012907 endingPage "608" @default.
• W2887012907 startingPage "600" @default.
• W2887012907 abstract "Temporal lobe epilepsy (TLE) is an acquired form of focal epilepsy, in which patients not only suffer from unprovoked, devastating seizures, but also from severe comorbidities, such as cognitive dysfunction. Correspondingly, several animal models of TLE exhibit memory dysfunction, especially spatial memory. The Morris water maze test is the most commonly used test for assessing spatial learning and memory in rodents. However, high stress and poor swimming abilities are common confounders and may contribute to misinterpretation. Particularly epileptic mice show altered behaviour during the test as they fail to understand the paradigm context. In the Barnes maze test, a dry-land maze test for spatial learning and memory that uses milder aversive stimuli, these drawbacks have not yet been reported. In the present study, we use this task to evaluate spatial learning and memory in the intrahippocampal kainic acid mouse model of TLE. We demonstrate that the epileptic mice understand the Barnes maze paradigm context, as they learn the location of the escape-chamber by using a serial search strategy but fail to develop the more efficient spatial search strategy. Our data indicate that the Barnes maze may be a better alternative to the Morris water maze for assessing search strategies and impairment of learning and memory in epileptic mice." @default.
• W2887012907 created "2018-08-22" @default.
• W2887012907 creator A5003282079 @default.
• W2887012907 creator A5017389205 @default.
• W2887012907 creator A5017463273 @default.
• W2887012907 creator A5060734194 @default.
• W2887012907 creator A5069126017 @default.
• W2887012907 creator A5069480056 @default.
• W2887012907 creator A5090159945 @default.
• W2887012907 date "2018-08-10" @default.
• W2887012907 modified "2023-10-13" @default.
• W2887012907 title "The Barnes Maze Task Reveals Specific Impairment of Spatial Learning Strategy in the Intrahippocampal Kainic Acid Model for Temporal Lobe Epilepsy" @default.
• W2887012907 cites W1906305879 @default.
• W2887012907 cites W1965826750 @default.
• W2887012907 cites W1970053249 @default.
• W2887012907 cites W1971306915 @default.
• W2887012907 cites W1979162851 @default.
• W2887012907 cites W1983937997 @default.
• W2887012907 cites W1984025514 @default.
• W2887012907 cites W2010847250 @default.
• W2887012907 cites W2012123457 @default.
• W2887012907 cites W2022224180 @default.
• W2887012907 cites W2023791666 @default.
• W2887012907 cites W2025005466 @default.
• W2887012907 cites W2039093344 @default.
• W2887012907 cites W2049069390 @default.
• W2887012907 cites W2054627364 @default.
• W2887012907 cites W2061404509 @default.
• W2887012907 cites W2064750784 @default.
• W2887012907 cites W2081752203 @default.
• W2887012907 cites W2082977820 @default.
• W2887012907 cites W2098957847 @default.
• W2887012907 cites W2103861118 @default.
• W2887012907 cites W2113299257 @default.
• W2887012907 cites W2123843070 @default.
• W2887012907 cites W2124852494 @default.
• W2887012907 cites W2169812612 @default.
• W2887012907 cites W2277463350 @default.
• W2887012907 cites W2472445743 @default.
• W2887012907 cites W2562329311 @default.
• W2887012907 cites W2563556615 @default.
• W2887012907 cites W4296816736 @default.
• W2887012907 doi "https://doi.org/10.1007/s11064-018-2610-z" @default.
• W2887012907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30097883" @default.
• W2887012907 hasPublicationYear "2018" @default.
• W2887012907 type Work @default.
• W2887012907 sameAs 2887012907 @default.
• W2887012907 citedByCount "22" @default.
• W2887012907 countsByYear W28870129072019 @default.
• W2887012907 countsByYear W28870129072020 @default.
• W2887012907 countsByYear W28870129072021 @default.
• W2887012907 countsByYear W28870129072022 @default.
• W2887012907 countsByYear W28870129072023 @default.
• W2887012907 crossrefType "journal-article" @default.
• W2887012907 hasAuthorship W2887012907A5003282079 @default.
• W2887012907 hasAuthorship W2887012907A5017389205 @default.
• W2887012907 hasAuthorship W2887012907A5017463273 @default.
• W2887012907 hasAuthorship W2887012907A5060734194 @default.
• W2887012907 hasAuthorship W2887012907A5069126017 @default.
• W2887012907 hasAuthorship W2887012907A5069480056 @default.
• W2887012907 hasAuthorship W2887012907A5090159945 @default.
• W2887012907 hasBestOaLocation W28870129072 @default.
• W2887012907 hasConcept C118552586 @default.
• W2887012907 hasConcept C12515866 @default.
• W2887012907 hasConcept C126322002 @default.
• W2887012907 hasConcept C151730666 @default.
• W2887012907 hasConcept C15744967 @default.
• W2887012907 hasConcept C169760540 @default.
• W2887012907 hasConcept C169900460 @default.
• W2887012907 hasConcept C170493617 @default.
• W2887012907 hasConcept C173586616 @default.
• W2887012907 hasConcept C180747234 @default.
• W2887012907 hasConcept C21963081 @default.
• W2887012907 hasConcept C2775858765 @default.
• W2887012907 hasConcept C2776108384 @default.
• W2887012907 hasConcept C2778186239 @default.
• W2887012907 hasConcept C2779343474 @default.
• W2887012907 hasConcept C2781099131 @default.
• W2887012907 hasConcept C2781161787 @default.
• W2887012907 hasConcept C2985665543 @default.
• W2887012907 hasConcept C3018842126 @default.
• W2887012907 hasConcept C43729271 @default.
• W2887012907 hasConcept C44752575 @default.
• W2887012907 hasConcept C558461103 @default.
• W2887012907 hasConcept C61174792 @default.
• W2887012907 hasConcept C71924100 @default.
• W2887012907 hasConcept C86803240 @default.
• W2887012907 hasConceptScore W2887012907C118552586 @default.
• W2887012907 hasConceptScore W2887012907C12515866 @default.
• W2887012907 hasConceptScore W2887012907C126322002 @default.
• W2887012907 hasConceptScore W2887012907C151730666 @default.
• W2887012907 hasConceptScore W2887012907C15744967 @default.
• W2887012907 hasConceptScore W2887012907C169760540 @default.
• W2887012907 hasConceptScore W2887012907C169900460 @default.
• W2887012907 hasConceptScore W2887012907C170493617 @default.
• W2887012907 hasConceptScore W2887012907C173586616 @default.
• W2887012907 hasConceptScore W2887012907C180747234 @default.
• W2887012907 hasConceptScore W2887012907C21963081 @default.

• next