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- W2887033958 endingPage "312" @default.
- W2887033958 startingPage "296" @default.
- W2887033958 abstract "Tissue hypoxia is a key feature of many important causes of morbidity and mortality. In pathologies such as stroke, peripheral vascular disease and ischaemic heart disease, hypoxia is largely a consequence of low blood flow induced ischaemia, hence perfusion imaging is often used as a surrogate for hypoxia to guide clinical diagnosis and treatment. Importantly, ischaemia and hypoxia are not synonymous conditions as it is not universally true that well perfused tissues are normoxic or that poorly perfused tissues are hypoxic. In pathologies such as cancer, for instance, perfusion imaging and oxygen concentration are less well correlated, and oxygen concentration is independently correlated to radiotherapy response and overall treatment outcomes. In addition, the progression of many diseases is intricately related to maladaptive responses to the hypoxia itself. Thus there is potentially great clinical and scientific utility in direct measurements of tissue oxygenation. Despite this, imaging assessment of hypoxia in patients is rarely performed in clinical settings. This review summarises some of the current methods used to clinically evaluate hypoxia, the barriers to the routine use of these methods and the newer agents and techniques being explored for the assessment of hypoxia in pathological processes." @default.
- W2887033958 created "2018-08-22" @default.
- W2887033958 creator A5010661645 @default.
- W2887033958 creator A5066472914 @default.
- W2887033958 creator A5087169102 @default.
- W2887033958 date "2018-10-01" @default.
- W2887033958 modified "2023-10-07" @default.
- W2887033958 title "Clinical imaging of hypoxia: Current status and future directions" @default.
- W2887033958 cites W1211413901 @default.
- W2887033958 cites W127654261 @default.
- W2887033958 cites W1480185538 @default.
- W2887033958 cites W1541649582 @default.
- W2887033958 cites W1578077707 @default.
- W2887033958 cites W1587146634 @default.
- W2887033958 cites W1599253395 @default.
- W2887033958 cites W1608567816 @default.
- W2887033958 cites W1890605084 @default.
- W2887033958 cites W1908733398 @default.
- W2887033958 cites W1963612485 @default.
- W2887033958 cites W1963704146 @default.
- W2887033958 cites W1964988634 @default.
- W2887033958 cites W1965741433 @default.
- W2887033958 cites W1966822881 @default.
- W2887033958 cites W1968999499 @default.
- W2887033958 cites W1969229854 @default.
- W2887033958 cites W1969460343 @default.
- W2887033958 cites W1973173610 @default.
- W2887033958 cites W1973870896 @default.
- W2887033958 cites W1975164617 @default.
- W2887033958 cites W1976395096 @default.
- W2887033958 cites W1976880272 @default.
- W2887033958 cites W1977060058 @default.
- W2887033958 cites W1977648108 @default.
- W2887033958 cites W1978963385 @default.
- W2887033958 cites W1979655949 @default.
- W2887033958 cites W1979665932 @default.
- W2887033958 cites W1980614613 @default.
- W2887033958 cites W1980640822 @default.
- W2887033958 cites W1981873263 @default.
- W2887033958 cites W1982513335 @default.
- W2887033958 cites W1982845574 @default.
- W2887033958 cites W1982952475 @default.
- W2887033958 cites W1982971396 @default.
- W2887033958 cites W1983270572 @default.
- W2887033958 cites W1983937835 @default.
- W2887033958 cites W1984199565 @default.
- W2887033958 cites W1984947150 @default.
- W2887033958 cites W1986371885 @default.
- W2887033958 cites W1987744854 @default.
- W2887033958 cites W1987904413 @default.
- W2887033958 cites W1988109237 @default.
- W2887033958 cites W1988315297 @default.
- W2887033958 cites W1989686400 @default.
- W2887033958 cites W1989951741 @default.
- W2887033958 cites W1990286868 @default.
- W2887033958 cites W1990835820 @default.
- W2887033958 cites W1991880013 @default.
- W2887033958 cites W1992070664 @default.
- W2887033958 cites W1992933063 @default.
- W2887033958 cites W1993480771 @default.
- W2887033958 cites W1993628822 @default.
- W2887033958 cites W1994134155 @default.
- W2887033958 cites W1994823419 @default.
- W2887033958 cites W1994988734 @default.
- W2887033958 cites W1995150247 @default.
- W2887033958 cites W1996124148 @default.
- W2887033958 cites W1996400431 @default.
- W2887033958 cites W1996927782 @default.
- W2887033958 cites W1996959321 @default.
- W2887033958 cites W1997023449 @default.
- W2887033958 cites W1997701630 @default.
- W2887033958 cites W1998230962 @default.
- W2887033958 cites W2000156247 @default.
- W2887033958 cites W2001431373 @default.
- W2887033958 cites W2001689281 @default.
- W2887033958 cites W2002660236 @default.
- W2887033958 cites W2003668572 @default.
- W2887033958 cites W2003670869 @default.
- W2887033958 cites W2004271709 @default.
- W2887033958 cites W2005760468 @default.
- W2887033958 cites W2006153373 @default.
- W2887033958 cites W2011343552 @default.
- W2887033958 cites W2011810742 @default.
- W2887033958 cites W2012023411 @default.
- W2887033958 cites W2012631304 @default.
- W2887033958 cites W2012747086 @default.
- W2887033958 cites W2013973949 @default.
- W2887033958 cites W2014062371 @default.
- W2887033958 cites W2014287318 @default.
- W2887033958 cites W2014455750 @default.
- W2887033958 cites W2014877216 @default.
- W2887033958 cites W2015602031 @default.
- W2887033958 cites W2016550302 @default.
- W2887033958 cites W2017014188 @default.
- W2887033958 cites W2017574292 @default.
- W2887033958 cites W2018722597 @default.
- W2887033958 cites W2019602861 @default.
- W2887033958 cites W2020634365 @default.