Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887067401> ?p ?o ?g. }
- W2887067401 endingPage "868" @default.
- W2887067401 startingPage "861" @default.
- W2887067401 abstract "Nicotine is one of the major components of electronic cigarette (e-cigarette) emissions. Nicotyrine is a product of nicotine dehydrogenation in e-vapor and is a known inhibitor of human cytochrome P450 enzyme, which mediates nicotine metabolism. However, the emission of nicotine and especially nicotyrine from e-cigarettes has not been studied under real-world vaping patterns. This study examined the impact of e-liquid composition, e-cigarette device power output, and vaping topography on nicotine and nicotyrine concentrations under real-world vaping patterns. The amount of nicotine emitted from e-cigarettes vaped at high e-liquid nicotine levels, high device power, and large puff volumes ranged from 0.365 μg/puff to 236 μg/puff and was comparable to the amount of nicotine emitted from regular cigarettes. E-cigarette coil temperatures (200-300 °C) favored the formation of nicotyrine: E-cigarette vaping generated 2- to 63-fold more nicotyrine per unit nicotine emission than conventional cigarette smoking. High nicotyrine emission from e-cigarettes indicates that nicotine metabolism could be potentially interrupted, which could lead to reduced e-cigarette usage, and result in lower exposures to toxic chemicals (e.g., formaldehyde and acetaldehyde). However, higher serum nicotine levels might increase cancer risks by stimulating nicotinic acetylcholine receptors (nAchRs)." @default.
- W2887067401 created "2018-08-22" @default.
- W2887067401 creator A5001699269 @default.
- W2887067401 creator A5015252389 @default.
- W2887067401 creator A5032322197 @default.
- W2887067401 creator A5033913836 @default.
- W2887067401 creator A5071394033 @default.
- W2887067401 creator A5072575291 @default.
- W2887067401 creator A5082490457 @default.
- W2887067401 date "2018-08-06" @default.
- W2887067401 modified "2023-10-14" @default.
- W2887067401 title "Evaluation of E-Vapor Nicotine and Nicotyrine Concentrations under Various E-Liquid Compositions, Device Settings, and Vaping Topographies" @default.
- W2887067401 cites W1774462230 @default.
- W2887067401 cites W1919298818 @default.
- W2887067401 cites W1964749017 @default.
- W2887067401 cites W1968393197 @default.
- W2887067401 cites W1994244053 @default.
- W2887067401 cites W1997650044 @default.
- W2887067401 cites W2002162388 @default.
- W2887067401 cites W2018653687 @default.
- W2887067401 cites W2022170808 @default.
- W2887067401 cites W2025625107 @default.
- W2887067401 cites W2032092418 @default.
- W2887067401 cites W2035490871 @default.
- W2887067401 cites W2040966135 @default.
- W2887067401 cites W2044613405 @default.
- W2887067401 cites W2045960403 @default.
- W2887067401 cites W2048096352 @default.
- W2887067401 cites W2061397591 @default.
- W2887067401 cites W2081974721 @default.
- W2887067401 cites W2087568344 @default.
- W2887067401 cites W2097622670 @default.
- W2887067401 cites W2113321910 @default.
- W2887067401 cites W2116438644 @default.
- W2887067401 cites W2120822158 @default.
- W2887067401 cites W2125844977 @default.
- W2887067401 cites W2144014211 @default.
- W2887067401 cites W2154171934 @default.
- W2887067401 cites W2169463741 @default.
- W2887067401 cites W2206759585 @default.
- W2887067401 cites W2236041697 @default.
- W2887067401 cites W2296894128 @default.
- W2887067401 cites W2314797955 @default.
- W2887067401 cites W2346645822 @default.
- W2887067401 cites W2404396929 @default.
- W2887067401 cites W2413415482 @default.
- W2887067401 cites W2474083423 @default.
- W2887067401 cites W2502355343 @default.
- W2887067401 cites W2558770367 @default.
- W2887067401 cites W2583959112 @default.
- W2887067401 cites W262820551 @default.
- W2887067401 cites W2792481089 @default.
- W2887067401 cites W4237535357 @default.
- W2887067401 cites W4240905658 @default.
- W2887067401 cites W4255642556 @default.
- W2887067401 cites W820190806 @default.
- W2887067401 doi "https://doi.org/10.1021/acs.chemrestox.8b00063" @default.
- W2887067401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6350771" @default.
- W2887067401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30080399" @default.
- W2887067401 hasPublicationYear "2018" @default.
- W2887067401 type Work @default.
- W2887067401 sameAs 2887067401 @default.
- W2887067401 citedByCount "25" @default.
- W2887067401 countsByYear W28870674012019 @default.
- W2887067401 countsByYear W28870674012020 @default.
- W2887067401 countsByYear W28870674012021 @default.
- W2887067401 countsByYear W28870674012022 @default.
- W2887067401 countsByYear W28870674012023 @default.
- W2887067401 crossrefType "journal-article" @default.
- W2887067401 hasAuthorship W2887067401A5001699269 @default.
- W2887067401 hasAuthorship W2887067401A5015252389 @default.
- W2887067401 hasAuthorship W2887067401A5032322197 @default.
- W2887067401 hasAuthorship W2887067401A5033913836 @default.
- W2887067401 hasAuthorship W2887067401A5071394033 @default.
- W2887067401 hasAuthorship W2887067401A5072575291 @default.
- W2887067401 hasAuthorship W2887067401A5082490457 @default.
- W2887067401 hasBestOaLocation W28870674012 @default.
- W2887067401 hasConcept C126322002 @default.
- W2887067401 hasConcept C170493617 @default.
- W2887067401 hasConcept C178790620 @default.
- W2887067401 hasConcept C185592680 @default.
- W2887067401 hasConcept C188987157 @default.
- W2887067401 hasConcept C2776970978 @default.
- W2887067401 hasConcept C2777595113 @default.
- W2887067401 hasConcept C2779547902 @default.
- W2887067401 hasConcept C2780161600 @default.
- W2887067401 hasConcept C55493867 @default.
- W2887067401 hasConcept C71924100 @default.
- W2887067401 hasConcept C98274493 @default.
- W2887067401 hasConceptScore W2887067401C126322002 @default.
- W2887067401 hasConceptScore W2887067401C170493617 @default.
- W2887067401 hasConceptScore W2887067401C178790620 @default.
- W2887067401 hasConceptScore W2887067401C185592680 @default.
- W2887067401 hasConceptScore W2887067401C188987157 @default.
- W2887067401 hasConceptScore W2887067401C2776970978 @default.
- W2887067401 hasConceptScore W2887067401C2777595113 @default.
- W2887067401 hasConceptScore W2887067401C2779547902 @default.
- W2887067401 hasConceptScore W2887067401C2780161600 @default.