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• W2887079247 abstract "In Brief Study Design. Epidemiological study. Objective. The aim of this study was to evaluate trends in the incidence of spinal infections (SI) and the possible role of substance use disorder (SUD) as a key associated factor. Summary of Background Data. SI pose major diagnostic and therapeutic challenge in developed countries, resulting in substantial morbidity and mortality. With an estimated incidence of up to 1:20,000, recent clinical experiences suggest that this rate may be rising. Methods. To evaluate a possible change in trend in the proportion of SI, we searched the Washington state Comprehensive Hospital Abstract Reporting System (CHARS) data during a period of 15 years. We retrieved ICD-9 and 10 codes, searching for all conditions that are regarded as SI (discitis, osteomyelitis, and intraspinal abscess), as well as major known SI-related risk factors. Results. We found that the proportion of SI among discharged patients had increased by around 40% during the past 6 years, starting at 2012 and increasing steadily thereafter. Analysis of SI-related risk factors within the group of SI revealed that proportion of SUD and malnutrition had undergone the most substantial change, with the former increasing >3-fold during the same period. Conclusion. Growing rates of drug abuse, drug dependence, and malnutrition throughout the State of Washington may trigger a substantial increase in the incidence of spinal infections in discharged patients. These findings may provide important insights in planning prevention strategies on a broader level. Level of Evidence: 4 The rate of spinal infections (SI) in developed countries may be increasing. Analysis of the Washington state CHARS database shows that the proportion of SI within discharged patients has increased by 40% in recent years and that the two main associated risk factors are substance use disorder and malnutrition." @default.
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• W2887079247 date "2019-02-15" @default.
• W2887079247 modified "2023-10-16" @default.
• W2887079247 title "Recent Increase in the Rate of Spinal Infections May be Related to Growing Substance-use Disorder in the State of Washington" @default.
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• W2887079247 doi "https://doi.org/10.1097/brs.0000000000002819" @default.
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