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• W2887168275 endingPage "9" @default.
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• W2887168275 abstract "Immunological impairment is a condition that is often observed in individuals with Down syndrome (DS). The immune response is modulated by pro- and anti-inflammatory cytokines whose expressions could be influenced by genetic polymorphisms. The present study was aimed at evaluating the frequencies of -174G>C, -572G>C, and -597G>A polymorphisms in the interleukin 6 (IL-6) gene and -592C>A, -1082A>G, and -819C>T polymorphisms in the IL-10 gene and the IL-6 and IL-10 serum levels in healthy individuals with and without DS. The authors also aimed to investigate the impact of the genotypes on the interleukin concentrations. The genetic polymorphisms were investigated in 200 DS individuals and 200 controls without DS. The serum measurement of IL-6 and IL-10 was performed in a subgroup (54 cases and 54 controls) by enzyme-linked immunosorbent assay (ELISA). The frequencies of the polymorphisms and haplotypes evaluated were not different between individuals with and without DS. IL-10 concentration was higher in DS children but was not influenced by IL-10 gene polymorphisms. IL-6 genotypes had no influence on IL-6 serum levels. The IL-10 serum levels are increased in DS individuals, but IL-10 polymorphisms are not the main factors that influence the IL-10 expression in DS." @default.
• W2887168275 created "2018-08-22" @default.
• W2887168275 creator A5004057788 @default.
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• W2887168275 creator A5048403425 @default.
• W2887168275 creator A5053046585 @default.
• W2887168275 date "2018-08-16" @default.
• W2887168275 modified "2023-10-15" @default.
• W2887168275 title "Interleukin 6 and 10 Serum Levels and Genetic Polymorphisms in Children with Down Syndrome" @default.
• W2887168275 cites W1515623324 @default.
• W2887168275 cites W1536916194 @default.
• W2887168275 cites W170042837 @default.
• W2887168275 cites W1778423053 @default.
• W2887168275 cites W1814457428 @default.
• W2887168275 cites W1878617291 @default.
• W2887168275 cites W1966043636 @default.
• W2887168275 cites W1968615956 @default.
• W2887168275 cites W1969393095 @default.
• W2887168275 cites W1970196309 @default.
• W2887168275 cites W1970297814 @default.
• W2887168275 cites W1977712559 @default.
• W2887168275 cites W1979096652 @default.
• W2887168275 cites W1981045717 @default.
• W2887168275 cites W1995990719 @default.
• W2887168275 cites W1998849703 @default.
• W2887168275 cites W2003165120 @default.
• W2887168275 cites W2006906895 @default.
• W2887168275 cites W2013382699 @default.
• W2887168275 cites W2016293419 @default.
• W2887168275 cites W2017749666 @default.
• W2887168275 cites W2017870772 @default.
• W2887168275 cites W2020209998 @default.
• W2887168275 cites W2021359684 @default.
• W2887168275 cites W2021721624 @default.
• W2887168275 cites W2023859552 @default.
• W2887168275 cites W2024904438 @default.
• W2887168275 cites W2025026247 @default.
• W2887168275 cites W2025690405 @default.
• W2887168275 cites W2027884712 @default.
• W2887168275 cites W2029080463 @default.
• W2887168275 cites W2031743210 @default.
• W2887168275 cites W2038689279 @default.
• W2887168275 cites W2040150142 @default.
• W2887168275 cites W2040635581 @default.
• W2887168275 cites W2050590372 @default.
• W2887168275 cites W2054046765 @default.
• W2887168275 cites W2063676575 @default.
• W2887168275 cites W2064759294 @default.
• W2887168275 cites W2068649643 @default.
• W2887168275 cites W2070039055 @default.
• W2887168275 cites W2075455573 @default.
• W2887168275 cites W2077372015 @default.
• W2887168275 cites W2079114300 @default.
• W2887168275 cites W2080834982 @default.
• W2887168275 cites W2082429191 @default.
• W2887168275 cites W2086707179 @default.
• W2887168275 cites W2089022749 @default.
• W2887168275 cites W2091379575 @default.
• W2887168275 cites W2091603080 @default.
• W2887168275 cites W2094647748 @default.
• W2887168275 cites W2096401612 @default.
• W2887168275 cites W2097412489 @default.
• W2887168275 cites W2098456470 @default.
• W2887168275 cites W2105385589 @default.
• W2887168275 cites W2110463517 @default.
• W2887168275 cites W2114712856 @default.
• W2887168275 cites W2119176746 @default.
• W2887168275 cites W2119274811 @default.
• W2887168275 cites W2124732757 @default.
• W2887168275 cites W2124899172 @default.
• W2887168275 cites W2126950194 @default.
• W2887168275 cites W2132229447 @default.
• W2887168275 cites W2136930121 @default.
• W2887168275 cites W2152777013 @default.
• W2887168275 cites W2157079522 @default.
• W2887168275 cites W2159671939 @default.
• W2887168275 cites W2160097418 @default.
• W2887168275 cites W2165092386 @default.
• W2887168275 cites W2166056111 @default.
• W2887168275 cites W2171739654 @default.
• W2887168275 cites W2186439683 @default.
• W2887168275 cites W2311736882 @default.
• W2887168275 cites W2341229217 @default.
• W2887168275 cites W2382916660 @default.
• W2887168275 cites W2496156788 @default.
• W2887168275 cites W2500199332 @default.
• W2887168275 cites W2508044717 @default.
• W2887168275 cites W2529586590 @default.
• W2887168275 cites W2532652981 @default.
• W2887168275 cites W2557174471 @default.
• W2887168275 cites W2587817005 @default.
• W2887168275 cites W2625304812 @default.
• W2887168275 cites W325881987 @default.
• W2887168275 cites W4231581694 @default.
• W2887168275 cites W981244039 @default.
• W2887168275 doi "https://doi.org/10.1155/2018/6539548" @default.

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