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- W2887184414 abstract "Background: Many studies have demonstrated that high residual platelet function in patients administered clopidogrel is associated with cardiovascular events, although, the majority of those studies examined the patients with coronary artery disease. We studied platelet function in patients with ischemic stroke treated by clopidogrel, and compared residual platelet function according to the severity of carotid disease. Methods: We measured platelet aggregation induced by ADP, VerifyNow P2Y12 assay (PRU), phosphorylation of vasodilator-stimulated phosphoprotein (PRI), platelet-leukocyte complex (PLC), and platelet p-selectin expression (PS) in 30 patients with ischemic stroke administered clopidogrel (21 males and 9 females, mean age was 65 years). We also measured platelet thrombus formation under arterial flow conditions using newly developed microchip-based flow chamber system. In this system, platelet thrombus formation was analyzed by measuring flow pressure changes due to occlusion of microchip and w..." @default.
- W2887184414 created "2018-08-22" @default.
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- W2887184414 date "2014-02-01" @default.
- W2887184414 modified "2023-09-23" @default.
- W2887184414 title "Abstract W P114: Assessment of Platelet Thrombus Formation in Patients with Carotid Disease Administered Clopidogrel" @default.
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