FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887202367> ?p ?o ?g. }

• W2887202367 endingPage "111" @default.
• W2887202367 startingPage "106" @default.
• W2887202367 abstract "Sulfur mustard (SM) is the most utilized chemical warfare agent in modern history and has caused more casualties than all other chemical weapons combined. SM still poses a threat to civilians globally because of existing stockpiles and ease of production. Exposure to SM causes irritation to the eyes and blistering of skin and respiratory tract. These clinical signs of exposure to SM can take 6-24 h to appear. Therefore, analyzing biomarkers of SM from biological specimens collected from suspected victims is necessary for diagnosis during this latent period. Here, we report a rapid, simple, and direct quantitative analytical method for an important and early SM biomarker, sulfur mustard oxide (SMO). The method includes addition of a stable isotope labeled internal standard, SMO extraction directly into dichloromethane (DCM), rapid drying and reconstitution of the extract, and direct analysis of SMO using gas chromatography-chemical ionization-mass spectrometry. The limit of detection of the method was 0.1 μM, with a linear range from 0.5 to 100 μM. Method selectivity, matrix effect, recovery, and short-term stability were also evaluated. Furthermore, the applicability of the method was tested by analyzing samples from inhalation exposure studies performed in swine. The method was able to detect SMO from 100% of the exposed swine (N = 9), with no interferences present in the plasma of the same swine prior to exposure. The method presented here is the first of its kind to allow for easy and rapid diagnosis of SM poisoning (sample analysis <15 min), especially important during the asymptomatic latency period." @default.
• W2887202367 created "2018-08-22" @default.
• W2887202367 creator A5000167876 @default.
• W2887202367 creator A5041044560 @default.
• W2887202367 creator A5042385983 @default.
• W2887202367 creator A5077938615 @default.
• W2887202367 date "2018-10-01" @default.
• W2887202367 modified "2023-09-27" @default.
• W2887202367 title "Rapid analysis of sulfur mustard oxide in plasma using gas chromatography-chemical ionization-mass spectrometry for diagnosis of sulfur mustard exposure" @default.
• W2887202367 cites W1971068003 @default.
• W2887202367 cites W1993934464 @default.
• W2887202367 cites W2001183112 @default.
• W2887202367 cites W2010581876 @default.
• W2887202367 cites W2015873842 @default.
• W2887202367 cites W2019121570 @default.
• W2887202367 cites W2028564378 @default.
• W2887202367 cites W2031324893 @default.
• W2887202367 cites W2053933342 @default.
• W2887202367 cites W2066193154 @default.
• W2887202367 cites W2075148158 @default.
• W2887202367 cites W2075625047 @default.
• W2887202367 cites W2083523507 @default.
• W2887202367 cites W2084391182 @default.
• W2887202367 cites W2090631453 @default.
• W2887202367 cites W2094533928 @default.
• W2887202367 cites W2098358677 @default.
• W2887202367 cites W2112977386 @default.
• W2887202367 cites W2127169900 @default.
• W2887202367 cites W2171941558 @default.
• W2887202367 cites W2209638 @default.
• W2887202367 cites W2321151248 @default.
• W2887202367 cites W2325298473 @default.
• W2887202367 cites W2335349054 @default.
• W2887202367 cites W2371640258 @default.
• W2887202367 cites W2412996289 @default.
• W2887202367 cites W2470926059 @default.
• W2887202367 cites W2791540062 @default.
• W2887202367 cites W2885019847 @default.
• W2887202367 cites W4242277823 @default.
• W2887202367 cites W4253592036 @default.
• W2887202367 cites W4294306270 @default.
• W2887202367 doi "https://doi.org/10.1016/j.chroma.2018.08.035" @default.
• W2887202367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30170867" @default.
• W2887202367 hasPublicationYear "2018" @default.
• W2887202367 type Work @default.
• W2887202367 sameAs 2887202367 @default.
• W2887202367 citedByCount "8" @default.
• W2887202367 countsByYear W28872023672019 @default.
• W2887202367 countsByYear W28872023672020 @default.
• W2887202367 countsByYear W28872023672021 @default.
• W2887202367 countsByYear W28872023672023 @default.
• W2887202367 crossrefType "journal-article" @default.
• W2887202367 hasAuthorship W2887202367A5000167876 @default.
• W2887202367 hasAuthorship W2887202367A5041044560 @default.
• W2887202367 hasAuthorship W2887202367A5042385983 @default.
• W2887202367 hasAuthorship W2887202367A5077938615 @default.
• W2887202367 hasConcept C119128265 @default.
• W2887202367 hasConcept C123460561 @default.
• W2887202367 hasConcept C145148216 @default.
• W2887202367 hasConcept C162356407 @default.
• W2887202367 hasConcept C178790620 @default.
• W2887202367 hasConcept C185592680 @default.
• W2887202367 hasConcept C198291218 @default.
• W2887202367 hasConcept C205345274 @default.
• W2887202367 hasConcept C25366896 @default.
• W2887202367 hasConcept C2780644109 @default.
• W2887202367 hasConcept C29730261 @default.
• W2887202367 hasConcept C43617362 @default.
• W2887202367 hasConcept C51884965 @default.
• W2887202367 hasConcept C518881349 @default.
• W2887202367 hasConceptScore W2887202367C119128265 @default.
• W2887202367 hasConceptScore W2887202367C123460561 @default.
• W2887202367 hasConceptScore W2887202367C145148216 @default.
• W2887202367 hasConceptScore W2887202367C162356407 @default.
• W2887202367 hasConceptScore W2887202367C178790620 @default.
• W2887202367 hasConceptScore W2887202367C185592680 @default.
• W2887202367 hasConceptScore W2887202367C198291218 @default.
• W2887202367 hasConceptScore W2887202367C205345274 @default.
• W2887202367 hasConceptScore W2887202367C25366896 @default.
• W2887202367 hasConceptScore W2887202367C2780644109 @default.
• W2887202367 hasConceptScore W2887202367C29730261 @default.
• W2887202367 hasConceptScore W2887202367C43617362 @default.
• W2887202367 hasConceptScore W2887202367C51884965 @default.
• W2887202367 hasConceptScore W2887202367C518881349 @default.
• W2887202367 hasFunder F4320332221 @default.
• W2887202367 hasFunder F4320333299 @default.
• W2887202367 hasLocation W28872023671 @default.
• W2887202367 hasLocation W28872023672 @default.
• W2887202367 hasOpenAccess W2887202367 @default.
• W2887202367 hasPrimaryLocation W28872023671 @default.
• W2887202367 hasRelatedWork W1969311896 @default.
• W2887202367 hasRelatedWork W1989479194 @default.
• W2887202367 hasRelatedWork W2002187212 @default.
• W2887202367 hasRelatedWork W2055537606 @default.
• W2887202367 hasRelatedWork W2058236355 @default.
• W2887202367 hasRelatedWork W2066217393 @default.
• W2887202367 hasRelatedWork W2089326028 @default.
• W2887202367 hasRelatedWork W2359472326 @default.

• next