FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887207938> ?p ?o ?g. }

• W2887207938 endingPage "120" @default.
• W2887207938 startingPage "109" @default.
• W2887207938 abstract "Plitidepsin is a marine-derived anticancer compound isolated from the Mediterranean tunicate Applidium albicans. It exerts pleiotropic effects on cancer cells, most likely by binding to the eukaryotic translation eEF1A2. This ultimately leads to cell-cycle arrest, growth inhibition and induction of apoptosis via multiple pathway alterations. Recently, a Phase III randomized trial in patients with relapsed/refractory multiple myeloma reported outcomes for plitidepsin plus dexamethasone compared with dexamethasone. Median progression-free survival was 3.8 months in the plitidepsin arm and 1.9 months in the dexamethasone arm (HR: 0.611; p = 0.0048). Here, we review preclinical data regarding plitidepsins mechanism of action, give an overview of clinical trial results across different tumor types as well as the latest results in multiple myeloma." @default.
• W2887207938 created "2018-08-22" @default.
• W2887207938 creator A5033064022 @default.
• W2887207938 creator A5039762705 @default.
• W2887207938 creator A5039994927 @default.
• W2887207938 date "2019-01-01" @default.
• W2887207938 modified "2023-09-29" @default.
• W2887207938 title "Plitidepsin: a potential new treatment for relapsed/refractory multiple myeloma" @default.
• W2887207938 cites W1514008151 @default.
• W2887207938 cites W1964109435 @default.
• W2887207938 cites W1964234385 @default.
• W2887207938 cites W1967719886 @default.
• W2887207938 cites W1970242518 @default.
• W2887207938 cites W1970304552 @default.
• W2887207938 cites W1976660231 @default.
• W2887207938 cites W1976843162 @default.
• W2887207938 cites W1983939149 @default.
• W2887207938 cites W1993685031 @default.
• W2887207938 cites W1997871580 @default.
• W2887207938 cites W1997961337 @default.
• W2887207938 cites W2003493540 @default.
• W2887207938 cites W2009096079 @default.
• W2887207938 cites W2017974132 @default.
• W2887207938 cites W2023010709 @default.
• W2887207938 cites W202658461 @default.
• W2887207938 cites W2029745149 @default.
• W2887207938 cites W2038212467 @default.
• W2887207938 cites W2043049816 @default.
• W2887207938 cites W2043450431 @default.
• W2887207938 cites W2044358283 @default.
• W2887207938 cites W2050662664 @default.
• W2887207938 cites W2051808283 @default.
• W2887207938 cites W2053937943 @default.
• W2887207938 cites W2053957621 @default.
• W2887207938 cites W2054056559 @default.
• W2887207938 cites W2055381555 @default.
• W2887207938 cites W2055576327 @default.
• W2887207938 cites W2056568168 @default.
• W2887207938 cites W2057528040 @default.
• W2887207938 cites W2075429227 @default.
• W2887207938 cites W2076392894 @default.
• W2887207938 cites W2101414374 @default.
• W2887207938 cites W2103409514 @default.
• W2887207938 cites W2106708030 @default.
• W2887207938 cites W2130030010 @default.
• W2887207938 cites W2130560812 @default.
• W2887207938 cites W2136541422 @default.
• W2887207938 cites W2137124821 @default.
• W2887207938 cites W2138349159 @default.
• W2887207938 cites W2141816218 @default.
• W2887207938 cites W2151549473 @default.
• W2887207938 cites W2152642419 @default.
• W2887207938 cites W2155417539 @default.
• W2887207938 cites W2156792347 @default.
• W2887207938 cites W2157202197 @default.
• W2887207938 cites W2162771614 @default.
• W2887207938 cites W2163188114 @default.
• W2887207938 cites W2422962677 @default.
• W2887207938 cites W2516177362 @default.
• W2887207938 cites W2528657877 @default.
• W2887207938 cites W2560322684 @default.
• W2887207938 cites W2564423063 @default.
• W2887207938 cites W2738322074 @default.
• W2887207938 cites W2781525129 @default.
• W2887207938 cites W4234294274 @default.
• W2887207938 doi "https://doi.org/10.2217/fon-2018-0492" @default.
• W2887207938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30111169" @default.
• W2887207938 hasPublicationYear "2019" @default.
• W2887207938 type Work @default.
• W2887207938 sameAs 2887207938 @default.
• W2887207938 citedByCount "39" @default.
• W2887207938 countsByYear W28872079382019 @default.
• W2887207938 countsByYear W28872079382020 @default.
• W2887207938 countsByYear W28872079382021 @default.
• W2887207938 countsByYear W28872079382022 @default.
• W2887207938 countsByYear W28872079382023 @default.
• W2887207938 crossrefType "journal-article" @default.
• W2887207938 hasAuthorship W2887207938A5033064022 @default.
• W2887207938 hasAuthorship W2887207938A5039762705 @default.
• W2887207938 hasAuthorship W2887207938A5039994927 @default.
• W2887207938 hasConcept C126322002 @default.
• W2887207938 hasConcept C142424586 @default.
• W2887207938 hasConcept C143998085 @default.
• W2887207938 hasConcept C190283241 @default.
• W2887207938 hasConcept C2776364478 @default.
• W2887207938 hasConcept C2780401358 @default.
• W2887207938 hasConcept C502942594 @default.
• W2887207938 hasConcept C55493867 @default.
• W2887207938 hasConcept C71924100 @default.
• W2887207938 hasConcept C86803240 @default.
• W2887207938 hasConcept C87355193 @default.
• W2887207938 hasConcept C98274493 @default.
• W2887207938 hasConceptScore W2887207938C126322002 @default.
• W2887207938 hasConceptScore W2887207938C142424586 @default.
• W2887207938 hasConceptScore W2887207938C143998085 @default.
• W2887207938 hasConceptScore W2887207938C190283241 @default.
• W2887207938 hasConceptScore W2887207938C2776364478 @default.
• W2887207938 hasConceptScore W2887207938C2780401358 @default.

• next