FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887312094> ?p ?o ?g. }

• W2887312094 abstract "Objective—Impaired regeneration of endothelial cells (EC) and overactivity of vascular smooth muscle cells (VSMC) are hallmarks of the arterial lesions associated with aging. The occurrence of 2 opposing cellular processes in the same arterial milieu makes pharmaceutical treatment difficult to develop. We previously reported that endothelial expression of a Notch ligand (Jagged1) was reduced in aged animals and that growth of the neointima was enhanced in these animals. Methods and Results—Similar to aged animals, Tie2-cre+ Jagged1lox/+ mice (with heterologous knockout of Jagged1 in EC) showed exaggerated intimal and medial thickening after carotid artery ligation. Unexpectedly, these mice showed little increase of Jagged1 expression not only in EC but also in VSMC, in contrast to a significant upregulation of Jagged1 in wild-type arteries after ligation. Coculture of VSMC with Jagged1-null EC resulted in the transition of VSMC from the contractile to the synthetic phenotype, along with decreased Jagged1 ..." @default.
• W2887312094 created "2018-08-22" @default.
• W2887312094 creator A5002353700 @default.
• W2887312094 creator A5028473757 @default.
• W2887312094 creator A5028742517 @default.
• W2887312094 creator A5047386514 @default.
• W2887312094 creator A5053718368 @default.
• W2887312094 creator A5055748731 @default.
• W2887312094 creator A5057466027 @default.
• W2887312094 creator A5072621951 @default.
• W2887312094 creator A5083102861 @default.
• W2887312094 creator A5087046763 @default.
• W2887312094 creator A5088588185 @default.
• W2887312094 creator A5090870676 @default.
• W2887312094 date "2011-09-01" @default.
• W2887312094 modified "2023-09-23" @default.
• W2887312094 title "Role of Jagged1 in Arterial Lesions After Vascular Injury" @default.
• W2887312094 hasPublicationYear "2011" @default.
• W2887312094 type Work @default.
• W2887312094 sameAs 2887312094 @default.
• W2887312094 citedByCount "0" @default.
• W2887312094 crossrefType "journal-article" @default.
• W2887312094 hasAuthorship W2887312094A5002353700 @default.
• W2887312094 hasAuthorship W2887312094A5028473757 @default.
• W2887312094 hasAuthorship W2887312094A5028742517 @default.
• W2887312094 hasAuthorship W2887312094A5047386514 @default.
• W2887312094 hasAuthorship W2887312094A5053718368 @default.
• W2887312094 hasAuthorship W2887312094A5055748731 @default.
• W2887312094 hasAuthorship W2887312094A5057466027 @default.
• W2887312094 hasAuthorship W2887312094A5072621951 @default.
• W2887312094 hasAuthorship W2887312094A5083102861 @default.
• W2887312094 hasAuthorship W2887312094A5087046763 @default.
• W2887312094 hasAuthorship W2887312094A5088588185 @default.
• W2887312094 hasAuthorship W2887312094A5090870676 @default.
• W2887312094 hasConcept C104317684 @default.
• W2887312094 hasConcept C105702510 @default.
• W2887312094 hasConcept C126322002 @default.
• W2887312094 hasConcept C127561419 @default.
• W2887312094 hasConcept C127716648 @default.
• W2887312094 hasConcept C134018914 @default.
• W2887312094 hasConcept C161879069 @default.
• W2887312094 hasConcept C170493617 @default.
• W2887312094 hasConcept C179437574 @default.
• W2887312094 hasConcept C182704531 @default.
• W2887312094 hasConcept C2777339539 @default.
• W2887312094 hasConcept C2777408375 @default.
• W2887312094 hasConcept C2778283817 @default.
• W2887312094 hasConcept C2778583881 @default.
• W2887312094 hasConcept C2779395532 @default.
• W2887312094 hasConcept C2992686903 @default.
• W2887312094 hasConcept C541997718 @default.
• W2887312094 hasConcept C55493867 @default.
• W2887312094 hasConcept C71924100 @default.
• W2887312094 hasConcept C86803240 @default.
• W2887312094 hasConcept C95444343 @default.
• W2887312094 hasConceptScore W2887312094C104317684 @default.
• W2887312094 hasConceptScore W2887312094C105702510 @default.
• W2887312094 hasConceptScore W2887312094C126322002 @default.
• W2887312094 hasConceptScore W2887312094C127561419 @default.
• W2887312094 hasConceptScore W2887312094C127716648 @default.
• W2887312094 hasConceptScore W2887312094C134018914 @default.
• W2887312094 hasConceptScore W2887312094C161879069 @default.
• W2887312094 hasConceptScore W2887312094C170493617 @default.
• W2887312094 hasConceptScore W2887312094C179437574 @default.
• W2887312094 hasConceptScore W2887312094C182704531 @default.
• W2887312094 hasConceptScore W2887312094C2777339539 @default.
• W2887312094 hasConceptScore W2887312094C2777408375 @default.
• W2887312094 hasConceptScore W2887312094C2778283817 @default.
• W2887312094 hasConceptScore W2887312094C2778583881 @default.
• W2887312094 hasConceptScore W2887312094C2779395532 @default.
• W2887312094 hasConceptScore W2887312094C2992686903 @default.
• W2887312094 hasConceptScore W2887312094C541997718 @default.
• W2887312094 hasConceptScore W2887312094C55493867 @default.
• W2887312094 hasConceptScore W2887312094C71924100 @default.
• W2887312094 hasConceptScore W2887312094C86803240 @default.
• W2887312094 hasConceptScore W2887312094C95444343 @default.
• W2887312094 hasLocation W28873120941 @default.
• W2887312094 hasOpenAccess W2887312094 @default.
• W2887312094 hasPrimaryLocation W28873120941 @default.
• W2887312094 hasRelatedWork W2001034681 @default.
• W2887312094 hasRelatedWork W2011424762 @default.
• W2887312094 hasRelatedWork W2021647932 @default.
• W2887312094 hasRelatedWork W2024936781 @default.
• W2887312094 hasRelatedWork W2026634708 @default.
• W2887312094 hasRelatedWork W2067633468 @default.
• W2887312094 hasRelatedWork W2093629921 @default.
• W2887312094 hasRelatedWork W2114429883 @default.
• W2887312094 hasRelatedWork W2119235794 @default.
• W2887312094 hasRelatedWork W2149847331 @default.
• W2887312094 hasRelatedWork W2165875870 @default.
• W2887312094 hasRelatedWork W2461591534 @default.
• W2887312094 hasRelatedWork W2465718697 @default.
• W2887312094 hasRelatedWork W2517481824 @default.
• W2887312094 hasRelatedWork W2608926462 @default.
• W2887312094 hasRelatedWork W2623542667 @default.
• W2887312094 hasRelatedWork W2768261145 @default.
• W2887312094 hasRelatedWork W2885099738 @default.
• W2887312094 hasRelatedWork W2970992908 @default.
• W2887312094 hasRelatedWork W3158597097 @default.
• W2887312094 isParatext "false" @default.

• next