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- W2887334857 abstract "Bacillus anthracis microorganisms are of historical and epidemiological importance and are among the most homogenous bacterial groups known, even though the B. anthracis genome is rich in mobile elements. Mobile elements can trigger the diversification of lineages; therefore, characterizing the extent of genomic variation in a large collection of strains is critical for a complete understanding of the diversity and evolution of the species. Here, we sequenced a large collection of B. anthracis strains (>400) that were recovered from human, animal, and environmental sources around the world. Our results confirmed the remarkable stability of gene content and synteny of the anthrax plasmids and revealed no signal of plasmid exchange between B. anthracis and pathogenic B. cereus isolates but rather predominantly vertical descent. These findings advance our understanding of the biology and pathogenomic evolution of B. anthracis and its plasmids." @default.
- W2887334857 created "2018-08-22" @default.
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- W2887334857 date "2018-08-28" @default.
- W2887334857 modified "2023-10-18" @default.
- W2887334857 title "Genomic Characterization and Copy Number Variation of <i>Bacillus anthracis</i> Plasmids pXO1 and pXO2 in a Historical Collection of 412 Strains" @default.
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- W2887334857 doi "https://doi.org/10.1128/msystems.00065-18" @default.
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