Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887441721> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2887441721 abstract "Objective— Angiotensin II (Ang II) exerts deleterious effect on the cerebral circulation through production of reactive oxygen species (ROS). However, the enzymatic source of the ROS has not been defined. We tested the hypothesis that Ang II impairs endothelium-dependent responses in the cerebral microcirculation through ROS generated in cerebrovascular cells by the enzyme NADPH oxidase. Methods and Results— Cerebral blood flow (CBF) was monitored by laser Doppler flowmetry in anesthetized mice equipped with a cranial window. Ang II (0.25±0.02 μg/kg per minute for 30 to 45 minutes) attenuated the CBF increase produced by the endothelium-dependent vasodilators acetylcholine (−42±5%; P<0.05), bradykinin (−53±5%; P<0.05), and A23187 (−43±4%; P<0.05), and induced cerebrovascular ROS production, assessed by hydroethidine fluoromicrography. These actions of Ang II were prevented by losartan, by the ROS scavenger Mn(III) tetrakis (4-benzoic acid) porphyrin chloride (100 μmol/L), or by the NADPH oxidase peptide i..." @default.
- W2887441721 created "2018-08-22" @default.
- W2887441721 creator A5007586146 @default.
- W2887441721 creator A5012689837 @default.
- W2887441721 creator A5032423488 @default.
- W2887441721 creator A5063378395 @default.
- W2887441721 creator A5065085463 @default.
- W2887441721 date "2006-04-01" @default.
- W2887441721 modified "2023-09-28" @default.
- W2887441721 title "Angiotensin II Attenuates Endothelium-Dependent Responses in the Cerebral Microcirculation Through Nox-2–Derived Radicals" @default.
- W2887441721 hasPublicationYear "2006" @default.
- W2887441721 type Work @default.
- W2887441721 sameAs 2887441721 @default.
- W2887441721 citedByCount "0" @default.
- W2887441721 crossrefType "journal-article" @default.
- W2887441721 hasAuthorship W2887441721A5007586146 @default.
- W2887441721 hasAuthorship W2887441721A5012689837 @default.
- W2887441721 hasAuthorship W2887441721A5032423488 @default.
- W2887441721 hasAuthorship W2887441721A5063378395 @default.
- W2887441721 hasAuthorship W2887441721A5065085463 @default.
- W2887441721 hasConcept C119671327 @default.
- W2887441721 hasConcept C120770815 @default.
- W2887441721 hasConcept C126322002 @default.
- W2887441721 hasConcept C12722491 @default.
- W2887441721 hasConcept C134018914 @default.
- W2887441721 hasConcept C157767197 @default.
- W2887441721 hasConcept C170493617 @default.
- W2887441721 hasConcept C185592680 @default.
- W2887441721 hasConcept C2776992346 @default.
- W2887441721 hasConcept C2779591629 @default.
- W2887441721 hasConcept C2779719074 @default.
- W2887441721 hasConcept C2780288358 @default.
- W2887441721 hasConcept C2908929049 @default.
- W2887441721 hasConcept C48349386 @default.
- W2887441721 hasConcept C519581460 @default.
- W2887441721 hasConcept C55493867 @default.
- W2887441721 hasConcept C71924100 @default.
- W2887441721 hasConcept C98274493 @default.
- W2887441721 hasConceptScore W2887441721C119671327 @default.
- W2887441721 hasConceptScore W2887441721C120770815 @default.
- W2887441721 hasConceptScore W2887441721C126322002 @default.
- W2887441721 hasConceptScore W2887441721C12722491 @default.
- W2887441721 hasConceptScore W2887441721C134018914 @default.
- W2887441721 hasConceptScore W2887441721C157767197 @default.
- W2887441721 hasConceptScore W2887441721C170493617 @default.
- W2887441721 hasConceptScore W2887441721C185592680 @default.
- W2887441721 hasConceptScore W2887441721C2776992346 @default.
- W2887441721 hasConceptScore W2887441721C2779591629 @default.
- W2887441721 hasConceptScore W2887441721C2779719074 @default.
- W2887441721 hasConceptScore W2887441721C2780288358 @default.
- W2887441721 hasConceptScore W2887441721C2908929049 @default.
- W2887441721 hasConceptScore W2887441721C48349386 @default.
- W2887441721 hasConceptScore W2887441721C519581460 @default.
- W2887441721 hasConceptScore W2887441721C55493867 @default.
- W2887441721 hasConceptScore W2887441721C71924100 @default.
- W2887441721 hasConceptScore W2887441721C98274493 @default.
- W2887441721 hasLocation W28874417211 @default.
- W2887441721 hasOpenAccess W2887441721 @default.
- W2887441721 hasPrimaryLocation W28874417211 @default.
- W2887441721 hasRelatedWork W1904408604 @default.
- W2887441721 hasRelatedWork W1983227355 @default.
- W2887441721 hasRelatedWork W1996326547 @default.
- W2887441721 hasRelatedWork W1996446769 @default.
- W2887441721 hasRelatedWork W2015777983 @default.
- W2887441721 hasRelatedWork W2018247049 @default.
- W2887441721 hasRelatedWork W2032387708 @default.
- W2887441721 hasRelatedWork W2049718570 @default.
- W2887441721 hasRelatedWork W2051570483 @default.
- W2887441721 hasRelatedWork W2058117129 @default.
- W2887441721 hasRelatedWork W2077688067 @default.
- W2887441721 hasRelatedWork W2093872504 @default.
- W2887441721 hasRelatedWork W2097267275 @default.
- W2887441721 hasRelatedWork W2107935856 @default.
- W2887441721 hasRelatedWork W2116052611 @default.
- W2887441721 hasRelatedWork W2141560283 @default.
- W2887441721 hasRelatedWork W2260165590 @default.
- W2887441721 hasRelatedWork W2325167761 @default.
- W2887441721 hasRelatedWork W2325334096 @default.
- W2887441721 hasRelatedWork W34898393 @default.
- W2887441721 isParatext "false" @default.
- W2887441721 isRetracted "false" @default.
- W2887441721 magId "2887441721" @default.
- W2887441721 workType "article" @default.