FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887449097> ?p ?o ?g. }

• W2887449097 endingPage "11" @default.
• W2887449097 startingPage "1" @default.
• W2887449097 abstract "Abstract Post-translational modification (PTM) serves as a regulatory mechanism for protein function, influencing their stability, interactions, activity and localization, and is critical in many signaling pathways. The best characterized PTM is phosphorylation, whereby a phosphate is added to an acceptor residue, most commonly serine, threonine and tyrosine in metazoans. As proteins are often phosphorylated at multiple sites, identifying those sites that are important for function is a challenging problem. Considering that any given phosphorylation site might be non-functional, prioritizing evolutionarily conserved phosphosites provides a general strategy to identify the putative functional sites. To facilitate the identification of conserved phosphosites, we generated a large-scale phosphoproteomics dataset from Drosophila embryos collected from six closely-related species. We built iProteinDB (https://www.flyrnai.org/tools/iproteindb/), a resource integrating these data with other high-throughput PTM datasets, including vertebrates, and manually curated information for Drosophila. At iProteinDB, scientists can view the PTM landscape for any Drosophila protein and identify predicted functional phosphosites based on a comparative analysis of data from closely-related Drosophila species. Further, iProteinDB enables comparison of PTM data from Drosophila to that of orthologous proteins from other model organisms, including human, mouse, rat, Xenopus tropicalis, Danio rerio, and Caenorhabditis elegans." @default.
• W2887449097 created "2018-08-22" @default.
• W2887449097 creator A5008456362 @default.
• W2887449097 creator A5008546370 @default.
• W2887449097 creator A5014672294 @default.
• W2887449097 creator A5020086690 @default.
• W2887449097 creator A5025902765 @default.
• W2887449097 creator A5026569214 @default.
• W2887449097 creator A5032288206 @default.
• W2887449097 creator A5041208558 @default.
• W2887449097 creator A5047976636 @default.
• W2887449097 creator A5050058340 @default.
• W2887449097 creator A5071083794 @default.
• W2887449097 date "2019-01-01" @default.
• W2887449097 modified "2023-10-02" @default.
• W2887449097 title "iProteinDB: An Integrative Database of <i>Drosophila</i> Post-translational Modifications" @default.
• W2887449097 cites W1490559159 @default.
• W2887449097 cites W1970180329 @default.
• W2887449097 cites W1978714931 @default.
• W2887449097 cites W1993450321 @default.
• W2887449097 cites W2004707197 @default.
• W2887449097 cites W2005893121 @default.
• W2887449097 cites W2011953977 @default.
• W2887449097 cites W2018732798 @default.
• W2887449097 cites W2024481695 @default.
• W2887449097 cites W2026926544 @default.
• W2887449097 cites W2042629507 @default.
• W2887449097 cites W2043274355 @default.
• W2887449097 cites W2048448217 @default.
• W2887449097 cites W2053679349 @default.
• W2887449097 cites W2078964925 @default.
• W2887449097 cites W2085037886 @default.
• W2887449097 cites W2102025585 @default.
• W2887449097 cites W2103479321 @default.
• W2887449097 cites W2104855680 @default.
• W2887449097 cites W2105039688 @default.
• W2887449097 cites W2106446195 @default.
• W2887449097 cites W2108270923 @default.
• W2887449097 cites W2120772351 @default.
• W2887449097 cites W2127774996 @default.
• W2887449097 cites W2129137060 @default.
• W2887449097 cites W2133347001 @default.
• W2887449097 cites W2141708714 @default.
• W2887449097 cites W2155521690 @default.
• W2887449097 cites W2157658519 @default.
• W2887449097 cites W2160620685 @default.
• W2887449097 cites W2162172965 @default.
• W2887449097 cites W2166884712 @default.
• W2887449097 cites W2167350014 @default.
• W2887449097 cites W2172609270 @default.
• W2887449097 cites W2316947589 @default.
• W2887449097 cites W2336330109 @default.
• W2887449097 cites W2413905035 @default.
• W2887449097 cites W2530330401 @default.
• W2887449097 cites W2604856406 @default.
• W2887449097 cites W2766510537 @default.
• W2887449097 cites W2781695784 @default.
• W2887449097 cites W2916483810 @default.
• W2887449097 doi "https://doi.org/10.1534/g3.118.200637" @default.
• W2887449097 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6325894" @default.
• W2887449097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30397019" @default.
• W2887449097 hasPublicationYear "2019" @default.
• W2887449097 type Work @default.
• W2887449097 sameAs 2887449097 @default.
• W2887449097 citedByCount "20" @default.
• W2887449097 countsByYear W28874490972019 @default.
• W2887449097 countsByYear W28874490972020 @default.
• W2887449097 countsByYear W28874490972021 @default.
• W2887449097 countsByYear W28874490972022 @default.
• W2887449097 countsByYear W28874490972023 @default.
• W2887449097 crossrefType "journal-article" @default.
• W2887449097 hasAuthorship W2887449097A5008456362 @default.
• W2887449097 hasAuthorship W2887449097A5008546370 @default.
• W2887449097 hasAuthorship W2887449097A5014672294 @default.
• W2887449097 hasAuthorship W2887449097A5020086690 @default.
• W2887449097 hasAuthorship W2887449097A5025902765 @default.
• W2887449097 hasAuthorship W2887449097A5026569214 @default.
• W2887449097 hasAuthorship W2887449097A5032288206 @default.
• W2887449097 hasAuthorship W2887449097A5041208558 @default.
• W2887449097 hasAuthorship W2887449097A5047976636 @default.
• W2887449097 hasAuthorship W2887449097A5050058340 @default.
• W2887449097 hasAuthorship W2887449097A5071083794 @default.
• W2887449097 hasBestOaLocation W28874490971 @default.
• W2887449097 hasConcept C104317684 @default.
• W2887449097 hasConcept C11960822 @default.
• W2887449097 hasConcept C14036430 @default.
• W2887449097 hasConcept C19843653 @default.
• W2887449097 hasConcept C2776041557 @default.
• W2887449097 hasConcept C2776878037 @default.
• W2887449097 hasConcept C2778944004 @default.
• W2887449097 hasConcept C2779535977 @default.
• W2887449097 hasConcept C2780104201 @default.
• W2887449097 hasConcept C2780384893 @default.
• W2887449097 hasConcept C54355233 @default.
• W2887449097 hasConcept C6675166 @default.
• W2887449097 hasConcept C70721500 @default.
• W2887449097 hasConcept C86803240 @default.
• W2887449097 hasConcept C87325107 @default.

• next