Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887479771> ?p ?o ?g. }
- W2887479771 endingPage "9009" @default.
- W2887479771 startingPage "8999" @default.
- W2887479771 abstract "The aim of this study is to explore the impact of sodium butyrate on d-glutamyl-meso-diaminopimelic acid (iE-DAP)-induced liver inflammation in dairy goats during subacute ruminal acidosis (SARA) caused by high-concentrate feed. To achieve this aim, 12 lactating dairy goats were randomly divided into two groups: a high-concentrate feed group (n = 6, concentrate/forage = 6:4) as the control group and a sodium butyrate (SB) with high-concentrate feed group (n = 6, concentrate/forage = 6:4, with 1% SB by wt.) as the treatment group. A rumen pH below 5.6 lasted for at least 4 h/d due to long-term HC feeding. The concentration of iE-DAP was significantly lower (11.67 ± 3.85 μg/mL, and 7.74 ± 1.46 μg/mL, at the fourth h and sixth h of feeding, respectively) in the SB-treated group than that in the HC group (51.45 ± 5.71 μg/mL, and 18.31 ± 3.83 μg/mL, at the fourth h and sixth h of feeding, respectively). Meanwhile, SB significantly suppressed the mRNA expression of inflammatory genes (NOD1, RIPK2, TAK1, NF-κB/p65, ERK, JNK2, p38, IL-1β, TNF-α, CCL5, CCL20, CXCL12, FOS, β-defensin/LAP). Moreover, the protein expression of NOD1, p-IκBα, p-NF-κB/p-p65, p-ERK1/2, p-JNK, p-p38, and HDAC3 was significantly downregulated in the HC+SB group. In conclusion, iE-DAP-induced inflammation and liver disruption generated by the HC diet was mitigated by SB treatment." @default.
- W2887479771 created "2018-08-22" @default.
- W2887479771 creator A5004524880 @default.
- W2887479771 creator A5029287707 @default.
- W2887479771 creator A5029394708 @default.
- W2887479771 creator A5051828116 @default.
- W2887479771 creator A5074220918 @default.
- W2887479771 creator A5080875885 @default.
- W2887479771 creator A5086160483 @default.
- W2887479771 date "2018-08-04" @default.
- W2887479771 modified "2023-10-15" @default.
- W2887479771 title "Sodium Butyrate Mitigates iE-DAP Induced Inflammation Caused by High-Concentrate Feeding in Liver of Dairy Goats" @default.
- W2887479771 cites W1023933234 @default.
- W2887479771 cites W1514224413 @default.
- W2887479771 cites W1515374196 @default.
- W2887479771 cites W1932869848 @default.
- W2887479771 cites W1972724111 @default.
- W2887479771 cites W1975456387 @default.
- W2887479771 cites W1976644844 @default.
- W2887479771 cites W1979942759 @default.
- W2887479771 cites W1991859140 @default.
- W2887479771 cites W1996251545 @default.
- W2887479771 cites W2001166572 @default.
- W2887479771 cites W2003342633 @default.
- W2887479771 cites W2003634035 @default.
- W2887479771 cites W2007807255 @default.
- W2887479771 cites W2016903073 @default.
- W2887479771 cites W2027748180 @default.
- W2887479771 cites W2039358501 @default.
- W2887479771 cites W2040024879 @default.
- W2887479771 cites W2041170922 @default.
- W2887479771 cites W2047203795 @default.
- W2887479771 cites W2048554259 @default.
- W2887479771 cites W2048838554 @default.
- W2887479771 cites W2052798287 @default.
- W2887479771 cites W2060145218 @default.
- W2887479771 cites W2069767327 @default.
- W2887479771 cites W2076162593 @default.
- W2887479771 cites W2083632951 @default.
- W2887479771 cites W2085901669 @default.
- W2887479771 cites W2090425151 @default.
- W2887479771 cites W2099562804 @default.
- W2887479771 cites W2106248075 @default.
- W2887479771 cites W2106455786 @default.
- W2887479771 cites W2117896755 @default.
- W2887479771 cites W2122859597 @default.
- W2887479771 cites W2134647004 @default.
- W2887479771 cites W2136736147 @default.
- W2887479771 cites W2138434619 @default.
- W2887479771 cites W2139539156 @default.
- W2887479771 cites W2145050940 @default.
- W2887479771 cites W2148572752 @default.
- W2887479771 cites W2156377275 @default.
- W2887479771 cites W2157262295 @default.
- W2887479771 cites W2165740748 @default.
- W2887479771 cites W2399125108 @default.
- W2887479771 cites W2443164227 @default.
- W2887479771 cites W2530971538 @default.
- W2887479771 cites W2549187569 @default.
- W2887479771 cites W2739011667 @default.
- W2887479771 cites W2770838672 @default.
- W2887479771 cites W2785076772 @default.
- W2887479771 cites W2787723470 @default.
- W2887479771 cites W2787783011 @default.
- W2887479771 cites W2788495074 @default.
- W2887479771 cites W2788976829 @default.
- W2887479771 cites W2789042417 @default.
- W2887479771 cites W4214830748 @default.
- W2887479771 doi "https://doi.org/10.1021/acs.jafc.8b02732" @default.
- W2887479771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30078321" @default.
- W2887479771 hasPublicationYear "2018" @default.
- W2887479771 type Work @default.
- W2887479771 sameAs 2887479771 @default.
- W2887479771 citedByCount "15" @default.
- W2887479771 countsByYear W28874797712019 @default.
- W2887479771 countsByYear W28874797712020 @default.
- W2887479771 countsByYear W28874797712021 @default.
- W2887479771 countsByYear W28874797712022 @default.
- W2887479771 countsByYear W28874797712023 @default.
- W2887479771 crossrefType "journal-article" @default.
- W2887479771 hasAuthorship W2887479771A5004524880 @default.
- W2887479771 hasAuthorship W2887479771A5029287707 @default.
- W2887479771 hasAuthorship W2887479771A5029394708 @default.
- W2887479771 hasAuthorship W2887479771A5051828116 @default.
- W2887479771 hasAuthorship W2887479771A5074220918 @default.
- W2887479771 hasAuthorship W2887479771A5080875885 @default.
- W2887479771 hasAuthorship W2887479771A5086160483 @default.
- W2887479771 hasConcept C100544194 @default.
- W2887479771 hasConcept C104317684 @default.
- W2887479771 hasConcept C126322002 @default.
- W2887479771 hasConcept C134018914 @default.
- W2887479771 hasConcept C140793950 @default.
- W2887479771 hasConcept C185592680 @default.
- W2887479771 hasConcept C2778942008 @default.
- W2887479771 hasConcept C55493867 @default.
- W2887479771 hasConcept C70262065 @default.
- W2887479771 hasConcept C71924100 @default.
- W2887479771 hasConcept C86803240 @default.