Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887533655> ?p ?o ?g. }
- W2887533655 endingPage "1041" @default.
- W2887533655 startingPage "1037" @default.
- W2887533655 abstract "The main objective of this work was to investigate the uptake channels of skin cells through which coumarin 6, transported by deoxycholate-mediated liposomes (DOC-LS), was internalised; this was also compared against the action of conventional LS. Coumarin 6-loaded DOC-LS and LS were characterised for size distribution, zeta potential, and shape, and analysed in vitro in human epidermal immortal keratinocyte (HaCaT) (epidermal) and human embryonic skin fibroblast (CCC-ESF-1) (dermal) cell lines. Various endocytosis inhibitors were incubated with cells treated with the nanocarriers. Flow cytometry results indicated that HaCaT and CCC-ESF-1 cells internalise the tested preparations through pinocytotic vesicles, macropinocytosis, clathrin-mediated endocytic pathways, and via lysosomes, which consume a considerable amount of energy. The endocytosis pathways of DOC-LS and LS showed no difference. This study provides a basis for the application of LS being combined with a microneedle system for efficient intracellular drug delivery, targeting cutaneous histocyte disorders." @default.
- W2887533655 created "2018-08-22" @default.
- W2887533655 creator A5003850660 @default.
- W2887533655 creator A5003866201 @default.
- W2887533655 creator A5023826377 @default.
- W2887533655 creator A5030978002 @default.
- W2887533655 creator A5058691896 @default.
- W2887533655 creator A5074014325 @default.
- W2887533655 creator A5089113644 @default.
- W2887533655 date "2018-10-24" @default.
- W2887533655 modified "2023-10-17" @default.
- W2887533655 title "DOC‐LS, a new liposome for dermal delivery, and its endocytosis by HaCaT and CCC‐ESF‐1 cells" @default.
- W2887533655 cites W1186931653 @default.
- W2887533655 cites W1319875 @default.
- W2887533655 cites W1436204951 @default.
- W2887533655 cites W1918793750 @default.
- W2887533655 cites W1964522149 @default.
- W2887533655 cites W1970128839 @default.
- W2887533655 cites W1985126638 @default.
- W2887533655 cites W1995673089 @default.
- W2887533655 cites W2067778485 @default.
- W2887533655 cites W2068377531 @default.
- W2887533655 cites W2075428301 @default.
- W2887533655 cites W2104309130 @default.
- W2887533655 cites W2113972541 @default.
- W2887533655 cites W2115280618 @default.
- W2887533655 cites W2115667311 @default.
- W2887533655 cites W2137093969 @default.
- W2887533655 cites W2158865030 @default.
- W2887533655 cites W2167806590 @default.
- W2887533655 cites W2193778092 @default.
- W2887533655 cites W2194181550 @default.
- W2887533655 cites W2275002695 @default.
- W2887533655 cites W2292391410 @default.
- W2887533655 cites W2293753681 @default.
- W2887533655 cites W2309646837 @default.
- W2887533655 cites W2322430535 @default.
- W2887533655 cites W2341058973 @default.
- W2887533655 cites W2357054495 @default.
- W2887533655 cites W2470890763 @default.
- W2887533655 cites W2551106897 @default.
- W2887533655 cites W2580021726 @default.
- W2887533655 cites W2617166728 @default.
- W2887533655 cites W69352699 @default.
- W2887533655 cites W808915020 @default.
- W2887533655 doi "https://doi.org/10.1049/iet-nbt.2018.5079" @default.
- W2887533655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30964010" @default.
- W2887533655 hasPublicationYear "2018" @default.
- W2887533655 type Work @default.
- W2887533655 sameAs 2887533655 @default.
- W2887533655 citedByCount "3" @default.
- W2887533655 countsByYear W28875336552023 @default.
- W2887533655 crossrefType "journal-article" @default.
- W2887533655 hasAuthorship W2887533655A5003850660 @default.
- W2887533655 hasAuthorship W2887533655A5003866201 @default.
- W2887533655 hasAuthorship W2887533655A5023826377 @default.
- W2887533655 hasAuthorship W2887533655A5030978002 @default.
- W2887533655 hasAuthorship W2887533655A5058691896 @default.
- W2887533655 hasAuthorship W2887533655A5074014325 @default.
- W2887533655 hasAuthorship W2887533655A5089113644 @default.
- W2887533655 hasBestOaLocation W28875336551 @default.
- W2887533655 hasConcept C118995209 @default.
- W2887533655 hasConcept C12554922 @default.
- W2887533655 hasConcept C1491633281 @default.
- W2887533655 hasConcept C178790620 @default.
- W2887533655 hasConcept C18150654 @default.
- W2887533655 hasConcept C185154212 @default.
- W2887533655 hasConcept C185592680 @default.
- W2887533655 hasConcept C202751555 @default.
- W2887533655 hasConcept C2778005187 @default.
- W2887533655 hasConcept C2779820397 @default.
- W2887533655 hasConcept C2780381497 @default.
- W2887533655 hasConcept C28005876 @default.
- W2887533655 hasConcept C40017333 @default.
- W2887533655 hasConcept C54355233 @default.
- W2887533655 hasConcept C55493867 @default.
- W2887533655 hasConcept C63162447 @default.
- W2887533655 hasConcept C79747257 @default.
- W2887533655 hasConcept C81885089 @default.
- W2887533655 hasConcept C86803240 @default.
- W2887533655 hasConcept C95444343 @default.
- W2887533655 hasConceptScore W2887533655C118995209 @default.
- W2887533655 hasConceptScore W2887533655C12554922 @default.
- W2887533655 hasConceptScore W2887533655C1491633281 @default.
- W2887533655 hasConceptScore W2887533655C178790620 @default.
- W2887533655 hasConceptScore W2887533655C18150654 @default.
- W2887533655 hasConceptScore W2887533655C185154212 @default.
- W2887533655 hasConceptScore W2887533655C185592680 @default.
- W2887533655 hasConceptScore W2887533655C202751555 @default.
- W2887533655 hasConceptScore W2887533655C2778005187 @default.
- W2887533655 hasConceptScore W2887533655C2779820397 @default.
- W2887533655 hasConceptScore W2887533655C2780381497 @default.
- W2887533655 hasConceptScore W2887533655C28005876 @default.
- W2887533655 hasConceptScore W2887533655C40017333 @default.
- W2887533655 hasConceptScore W2887533655C54355233 @default.
- W2887533655 hasConceptScore W2887533655C55493867 @default.
- W2887533655 hasConceptScore W2887533655C63162447 @default.
- W2887533655 hasConceptScore W2887533655C79747257 @default.