Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887554198> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2887554198 endingPage "287" @default.
- W2887554198 startingPage "280" @default.
- W2887554198 abstract "Studies have suggested that high-density lipoprotein (HDL) stimulates scavenger receptor class B type 1 (SR-B1) to promote hepatic uptake of cholesterol. SR-B1 is encoded by scavenger receptor class B member 1 (SCARB1) gene in human. A rare mutation in SCARB1 gene has been associated with coronary heart disease (CHD). A polymorphism rs5888 of SCARB1 gene has been linked to CHD risk in humans. The objective was to investigate the relationship between the SCARB1 gene polymorphism rs5888 and risk of CHD. We searched databases of case-control studies and cohort studies on rs5888 polymorphism of SCARB1 gene and risk of CHD. Two reviewers independently screened literature, extracted data, and estimated potential bias of included studies. The quality of the studies was evaluated by recommendation of Newcastle-Ottawa Scale (NOS). Meta-analysis was performed with Stata 12.0 software. Seven studies including 6360 subjects (cases: 2456, controls: 3904) were included in the final data combination. Meta-analysis showed T allele had a lower risk of CHD as compared to C allele in allele model (T vs. C: OR = 0.87, 95% CI: 0.70 to 1.09, P = 0.229). Moreover, we found that T allele or TT/TC had a lower risk of CHD as compared to C/CC in male in allele model (T vs. C: OR = 0.79, 95% CI: 0.61 to 1.01). However, no significant association was observed in women in all allele models. Our findings suggested that polymorphism rs5888 had negative association with CHD, especially in male. However, the conclusion needs further verification with high quality studies with larger sample size and rigorous designs." @default.
- W2887554198 created "2018-08-22" @default.
- W2887554198 creator A5024895966 @default.
- W2887554198 creator A5057477569 @default.
- W2887554198 creator A5077397027 @default.
- W2887554198 date "2018-12-01" @default.
- W2887554198 modified "2023-10-01" @default.
- W2887554198 title "SCARB1 rs5888 gene polymorphisms in coronary heart disease: A systematic review and a meta-analysis" @default.
- W2887554198 cites W1985170971 @default.
- W2887554198 cites W2054869306 @default.
- W2887554198 cites W2084588383 @default.
- W2887554198 cites W2092392634 @default.
- W2887554198 cites W2107098603 @default.
- W2887554198 cites W2112235767 @default.
- W2887554198 cites W2113865951 @default.
- W2887554198 cites W2116475791 @default.
- W2887554198 cites W2141485475 @default.
- W2887554198 cites W2156166773 @default.
- W2887554198 cites W2172173472 @default.
- W2887554198 cites W2239411994 @default.
- W2887554198 cites W2275204317 @default.
- W2887554198 cites W2277439059 @default.
- W2887554198 cites W2279717914 @default.
- W2887554198 cites W2327172638 @default.
- W2887554198 cites W2561460915 @default.
- W2887554198 cites W2571465655 @default.
- W2887554198 cites W2587804655 @default.
- W2887554198 cites W2597132418 @default.
- W2887554198 cites W2599703012 @default.
- W2887554198 cites W2610866811 @default.
- W2887554198 cites W2620331735 @default.
- W2887554198 cites W2765089908 @default.
- W2887554198 cites W2765954021 @default.
- W2887554198 cites W2768555410 @default.
- W2887554198 cites W2793841322 @default.
- W2887554198 cites W2794922331 @default.
- W2887554198 cites W810916275 @default.
- W2887554198 doi "https://doi.org/10.1016/j.gene.2018.08.024" @default.
- W2887554198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30103009" @default.
- W2887554198 hasPublicationYear "2018" @default.
- W2887554198 type Work @default.
- W2887554198 sameAs 2887554198 @default.
- W2887554198 citedByCount "14" @default.
- W2887554198 countsByYear W28875541982018 @default.
- W2887554198 countsByYear W28875541982020 @default.
- W2887554198 countsByYear W28875541982021 @default.
- W2887554198 countsByYear W28875541982022 @default.
- W2887554198 countsByYear W28875541982023 @default.
- W2887554198 crossrefType "journal-article" @default.
- W2887554198 hasAuthorship W2887554198A5024895966 @default.
- W2887554198 hasAuthorship W2887554198A5057477569 @default.
- W2887554198 hasAuthorship W2887554198A5077397027 @default.
- W2887554198 hasConcept C104317684 @default.
- W2887554198 hasConcept C126322002 @default.
- W2887554198 hasConcept C134018914 @default.
- W2887554198 hasConcept C180754005 @default.
- W2887554198 hasConcept C2778163477 @default.
- W2887554198 hasConcept C2780072125 @default.
- W2887554198 hasConcept C41443022 @default.
- W2887554198 hasConcept C54355233 @default.
- W2887554198 hasConcept C71924100 @default.
- W2887554198 hasConcept C86803240 @default.
- W2887554198 hasConcept C95190672 @default.
- W2887554198 hasConceptScore W2887554198C104317684 @default.
- W2887554198 hasConceptScore W2887554198C126322002 @default.
- W2887554198 hasConceptScore W2887554198C134018914 @default.
- W2887554198 hasConceptScore W2887554198C180754005 @default.
- W2887554198 hasConceptScore W2887554198C2778163477 @default.
- W2887554198 hasConceptScore W2887554198C2780072125 @default.
- W2887554198 hasConceptScore W2887554198C41443022 @default.
- W2887554198 hasConceptScore W2887554198C54355233 @default.
- W2887554198 hasConceptScore W2887554198C71924100 @default.
- W2887554198 hasConceptScore W2887554198C86803240 @default.
- W2887554198 hasConceptScore W2887554198C95190672 @default.
- W2887554198 hasLocation W28875541981 @default.
- W2887554198 hasLocation W28875541982 @default.
- W2887554198 hasOpenAccess W2887554198 @default.
- W2887554198 hasPrimaryLocation W28875541981 @default.
- W2887554198 hasRelatedWork W1970327593 @default.
- W2887554198 hasRelatedWork W1988517967 @default.
- W2887554198 hasRelatedWork W2002128513 @default.
- W2887554198 hasRelatedWork W2010403799 @default.
- W2887554198 hasRelatedWork W2057739827 @default.
- W2887554198 hasRelatedWork W2070922469 @default.
- W2887554198 hasRelatedWork W2171277769 @default.
- W2887554198 hasRelatedWork W2223919059 @default.
- W2887554198 hasRelatedWork W3165452661 @default.
- W2887554198 hasRelatedWork W2092874662 @default.
- W2887554198 hasVolume "678" @default.
- W2887554198 isParatext "false" @default.
- W2887554198 isRetracted "false" @default.
- W2887554198 magId "2887554198" @default.
- W2887554198 workType "article" @default.