Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887631404> ?p ?o ?g. }
- W2887631404 abstract "All oral P2Y12 receptor blockers are associated with some degree of delayed onset and offset of pharmacodynamic (PD) effects in patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention (PCI). Although intravenous glycoprotein IIb/IIIa inhibitors are associated with rapid onset of action, they are also associated with delayed offset and other limitations such as elevated bleeding risk and thrombocytopenia. Areas covered: In this review, the authors focus on cangrelor, an intravenous, reversible P2Y12 receptor blocker with fast onset and offset of effects. The authors also describe the pharmacologic effects of cangrelor and its pharmacologic interaction with other P2Y12 receptor inhibitors. Finally, the authors discuss the large-scale clinical trials that compared the efficacy and safety of cangrelor with clopidogrel. Expert opinion: In ACS patients undergoing PCI, cangrelor is most desirable to effectively prevent periprocedural ischemic events and to avoid excessive bleeding. Indeed, any high-risk patient with ST-segment elevation myocardial infraction or patient who is unable to take oral medications is a potential candidate for intravenous cangrelor therapy. Furthermore, stable patients with coronary artery disease, who are considered for ad hoc PCI following coronary angiography, may be considered for treatment with cangrelor to reduce post-PCI thrombotic events." @default.
- W2887631404 created "2018-08-22" @default.
- W2887631404 creator A5011626347 @default.
- W2887631404 creator A5012918602 @default.
- W2887631404 creator A5039130551 @default.
- W2887631404 creator A5041799937 @default.
- W2887631404 creator A5067935886 @default.
- W2887631404 date "2018-08-13" @default.
- W2887631404 modified "2023-09-24" @default.
- W2887631404 title "Cangrelor for the treatment of patients with Arterial Thrombosis" @default.
- W2887631404 cites W1949231367 @default.
- W2887631404 cites W1963879877 @default.
- W2887631404 cites W1966433445 @default.
- W2887631404 cites W1973911240 @default.
- W2887631404 cites W1986455514 @default.
- W2887631404 cites W1986775812 @default.
- W2887631404 cites W1989000968 @default.
- W2887631404 cites W1990018236 @default.
- W2887631404 cites W2006624707 @default.
- W2887631404 cites W20146419 @default.
- W2887631404 cites W2017385272 @default.
- W2887631404 cites W2022537971 @default.
- W2887631404 cites W2030753117 @default.
- W2887631404 cites W2040767703 @default.
- W2887631404 cites W2065390746 @default.
- W2887631404 cites W2068295374 @default.
- W2887631404 cites W2071686230 @default.
- W2887631404 cites W2077429173 @default.
- W2887631404 cites W2078644068 @default.
- W2887631404 cites W2079311486 @default.
- W2887631404 cites W2086658843 @default.
- W2887631404 cites W2096488065 @default.
- W2887631404 cites W2122776876 @default.
- W2887631404 cites W2123112974 @default.
- W2887631404 cites W2125043491 @default.
- W2887631404 cites W2125093797 @default.
- W2887631404 cites W2136228924 @default.
- W2887631404 cites W2137746198 @default.
- W2887631404 cites W2143277746 @default.
- W2887631404 cites W2146258814 @default.
- W2887631404 cites W2149011208 @default.
- W2887631404 cites W2149069933 @default.
- W2887631404 cites W2150655309 @default.
- W2887631404 cites W2150934225 @default.
- W2887631404 cites W2152823642 @default.
- W2887631404 cites W2153107785 @default.
- W2887631404 cites W2153447053 @default.
- W2887631404 cites W2159980301 @default.
- W2887631404 cites W2161055506 @default.
- W2887631404 cites W2165248515 @default.
- W2887631404 cites W2165983414 @default.
- W2887631404 cites W2170029016 @default.
- W2887631404 cites W2170312517 @default.
- W2887631404 cites W2480930200 @default.
- W2887631404 cites W2532584865 @default.
- W2887631404 cites W35937193 @default.
- W2887631404 doi "https://doi.org/10.1080/14656566.2018.1506767" @default.
- W2887631404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30102083" @default.
- W2887631404 hasPublicationYear "2018" @default.
- W2887631404 type Work @default.
- W2887631404 sameAs 2887631404 @default.
- W2887631404 citedByCount "5" @default.
- W2887631404 countsByYear W28876314042020 @default.
- W2887631404 countsByYear W28876314042021 @default.
- W2887631404 countsByYear W28876314042022 @default.
- W2887631404 crossrefType "journal-article" @default.
- W2887631404 hasAuthorship W2887631404A5011626347 @default.
- W2887631404 hasAuthorship W2887631404A5012918602 @default.
- W2887631404 hasAuthorship W2887631404A5039130551 @default.
- W2887631404 hasAuthorship W2887631404A5041799937 @default.
- W2887631404 hasAuthorship W2887631404A5067935886 @default.
- W2887631404 hasConcept C126322002 @default.
- W2887631404 hasConcept C164705383 @default.
- W2887631404 hasConcept C2776708134 @default.
- W2887631404 hasConcept C2777849778 @default.
- W2887631404 hasConcept C2778213512 @default.
- W2887631404 hasConcept C2780400711 @default.
- W2887631404 hasConcept C42219234 @default.
- W2887631404 hasConcept C45393284 @default.
- W2887631404 hasConcept C49059817 @default.
- W2887631404 hasConcept C500558357 @default.
- W2887631404 hasConcept C71924100 @default.
- W2887631404 hasConceptScore W2887631404C126322002 @default.
- W2887631404 hasConceptScore W2887631404C164705383 @default.
- W2887631404 hasConceptScore W2887631404C2776708134 @default.
- W2887631404 hasConceptScore W2887631404C2777849778 @default.
- W2887631404 hasConceptScore W2887631404C2778213512 @default.
- W2887631404 hasConceptScore W2887631404C2780400711 @default.
- W2887631404 hasConceptScore W2887631404C42219234 @default.
- W2887631404 hasConceptScore W2887631404C45393284 @default.
- W2887631404 hasConceptScore W2887631404C49059817 @default.
- W2887631404 hasConceptScore W2887631404C500558357 @default.
- W2887631404 hasConceptScore W2887631404C71924100 @default.
- W2887631404 hasFunder F4320313519 @default.
- W2887631404 hasLocation W28876314041 @default.
- W2887631404 hasLocation W28876314042 @default.
- W2887631404 hasOpenAccess W2887631404 @default.
- W2887631404 hasPrimaryLocation W28876314041 @default.
- W2887631404 hasRelatedWork W2054673562 @default.
- W2887631404 hasRelatedWork W2136228924 @default.