FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887667412> ?p ?o ?g. }

• W2887667412 endingPage "237" @default.
• W2887667412 startingPage "228" @default.
• W2887667412 abstract "Hepatic progenitor cells (HPCs) might be the origin of hepatocellular carcinoma. 1α,25-Dihydroxyvitamin D3 (1,25(OH)2D3) (VD3) has been documented as an anticancer agent for various cancers. However, the potential effect of VD3 on the proliferation and malignant transformation of HPCs induced by aflatoxin B1 (AFB1) has not been determined. In this study, we found that AFB1 exhibited the stimulative effects on the proliferation, dedifferentiation and invasion of HPCs via activating AKT pathway but turning off Hippo pathway, which were terminated when VD3 was used in combination with AFB1. Furthermore, in AFB1-induced liver damage mouse model, VD3 also showed protective effect by reducing HPCs population. Together, these preclinical data not only provide a newly identified mechanism by which AFB1 affects HPCs but also strengthen the idea of developing VD3 as an anticancer agent." @default.
• W2887667412 created "2018-08-22" @default.
• W2887667412 creator A5004525919 @default.
• W2887667412 creator A5019005078 @default.
• W2887667412 creator A5032764121 @default.
• W2887667412 creator A5040643779 @default.
• W2887667412 creator A5052081480 @default.
• W2887667412 creator A5068831165 @default.
• W2887667412 creator A5088821585 @default.
• W2887667412 creator A5091070290 @default.
• W2887667412 creator A5091702167 @default.
• W2887667412 date "2018-10-01" @default.
• W2887667412 modified "2023-10-12" @default.
• W2887667412 title "1α,25-Dihydroxyvitamin D3 inhibits aflatoxin B1-induced proliferation and dedifferentiation of hepatic progenitor cells by regulating PI3K/Akt and Hippo pathways" @default.
• W2887667412 cites W1592523122 @default.
• W2887667412 cites W1963927300 @default.
• W2887667412 cites W1975633931 @default.
• W2887667412 cites W1975883803 @default.
• W2887667412 cites W1982786429 @default.
• W2887667412 cites W1990553788 @default.
• W2887667412 cites W1990765314 @default.
• W2887667412 cites W2020994990 @default.
• W2887667412 cites W2023471348 @default.
• W2887667412 cites W2040032718 @default.
• W2887667412 cites W2049988916 @default.
• W2887667412 cites W2061357996 @default.
• W2887667412 cites W2067592231 @default.
• W2887667412 cites W2074804593 @default.
• W2887667412 cites W2079105341 @default.
• W2887667412 cites W2092517002 @default.
• W2887667412 cites W2093128801 @default.
• W2887667412 cites W2107297677 @default.
• W2887667412 cites W2117297406 @default.
• W2887667412 cites W2119739932 @default.
• W2887667412 cites W2147182415 @default.
• W2887667412 cites W2149226545 @default.
• W2887667412 cites W2167825227 @default.
• W2887667412 cites W2198024467 @default.
• W2887667412 cites W2204493619 @default.
• W2887667412 cites W2515120301 @default.
• W2887667412 cites W2515649331 @default.
• W2887667412 cites W2557860064 @default.
• W2887667412 cites W4211173486 @default.
• W2887667412 cites W4254164242 @default.
• W2887667412 doi "https://doi.org/10.1016/j.jsbmb.2018.08.002" @default.
• W2887667412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30099061" @default.
• W2887667412 hasPublicationYear "2018" @default.
• W2887667412 type Work @default.
• W2887667412 sameAs 2887667412 @default.
• W2887667412 citedByCount "11" @default.
• W2887667412 countsByYear W28876674122019 @default.
• W2887667412 countsByYear W28876674122021 @default.
• W2887667412 countsByYear W28876674122022 @default.
• W2887667412 countsByYear W28876674122023 @default.
• W2887667412 crossrefType "journal-article" @default.
• W2887667412 hasAuthorship W2887667412A5004525919 @default.
• W2887667412 hasAuthorship W2887667412A5019005078 @default.
• W2887667412 hasAuthorship W2887667412A5032764121 @default.
• W2887667412 hasAuthorship W2887667412A5040643779 @default.
• W2887667412 hasAuthorship W2887667412A5052081480 @default.
• W2887667412 hasAuthorship W2887667412A5068831165 @default.
• W2887667412 hasAuthorship W2887667412A5088821585 @default.
• W2887667412 hasAuthorship W2887667412A5091070290 @default.
• W2887667412 hasAuthorship W2887667412A5091702167 @default.
• W2887667412 hasConcept C126322002 @default.
• W2887667412 hasConcept C172512520 @default.
• W2887667412 hasConcept C201750760 @default.
• W2887667412 hasConcept C28328180 @default.
• W2887667412 hasConcept C31903555 @default.
• W2887667412 hasConcept C40758303 @default.
• W2887667412 hasConcept C502942594 @default.
• W2887667412 hasConcept C62478195 @default.
• W2887667412 hasConcept C71924100 @default.
• W2887667412 hasConcept C75217442 @default.
• W2887667412 hasConcept C86554907 @default.
• W2887667412 hasConcept C86803240 @default.
• W2887667412 hasConcept C95444343 @default.
• W2887667412 hasConceptScore W2887667412C126322002 @default.
• W2887667412 hasConceptScore W2887667412C172512520 @default.
• W2887667412 hasConceptScore W2887667412C201750760 @default.
• W2887667412 hasConceptScore W2887667412C28328180 @default.
• W2887667412 hasConceptScore W2887667412C31903555 @default.
• W2887667412 hasConceptScore W2887667412C40758303 @default.
• W2887667412 hasConceptScore W2887667412C502942594 @default.
• W2887667412 hasConceptScore W2887667412C62478195 @default.
• W2887667412 hasConceptScore W2887667412C71924100 @default.
• W2887667412 hasConceptScore W2887667412C75217442 @default.
• W2887667412 hasConceptScore W2887667412C86554907 @default.
• W2887667412 hasConceptScore W2887667412C86803240 @default.
• W2887667412 hasConceptScore W2887667412C95444343 @default.
• W2887667412 hasFunder F4320321001 @default.
• W2887667412 hasLocation W28876674121 @default.
• W2887667412 hasOpenAccess W2887667412 @default.
• W2887667412 hasPrimaryLocation W28876674121 @default.
• W2887667412 hasRelatedWork W1988747615 @default.
• W2887667412 hasRelatedWork W2026140947 @default.
• W2887667412 hasRelatedWork W2044505245 @default.
• W2887667412 hasRelatedWork W2376211306 @default.

• next