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• W2887681716 abstract "Pemphigus vulgaris (PV) is a severe autoimmune blistering disease caused by auto-antibodies (auto-Abs) directed against epithelial desmosomal components and leading to disruption of cell-cell adhesion. The exact mechanisms underlying the disease pathogenesis remain unknown and treatment is still based on immunosuppressive drugs, such as corticosteroids, which are associated with potentially significant side effects. Ethnic susceptibility, familial occurrence, and autoimmune comorbidity, suggest a genetic component to the pathogenesis of the disease, which, if discovered, could advance our understanding of PV pathogenesis and thereby point to novel therapeutic targets for this life-threatening disorder. In this article, we review the evidence for a genetic basis of PV, summarize the different approaches used to investigate susceptibility traits for the disease and describe past and recent discoveries regarding genes associated with PV, most of which belong to the human leukocyte antigen (HLA) locus with limited data regarding association of non-HLA genes with the disease." @default.
• W2887681716 created "2018-08-22" @default.
• W2887681716 creator A5029436306 @default.
• W2887681716 creator A5050718731 @default.
• W2887681716 creator A5058466124 @default.
• W2887681716 date "2018-08-14" @default.
• W2887681716 modified "2023-10-09" @default.
• W2887681716 title "The Genetics of Pemphigus Vulgaris" @default.
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• W2887681716 cites W1482923163 @default.
• W2887681716 cites W1497954397 @default.
• W2887681716 cites W1568431196 @default.
• W2887681716 cites W1922254653 @default.
• W2887681716 cites W1930672388 @default.
• W2887681716 cites W1967524850 @default.
• W2887681716 cites W1975411472 @default.
• W2887681716 cites W1979166933 @default.
• W2887681716 cites W1979192511 @default.
• W2887681716 cites W1981416665 @default.
• W2887681716 cites W1991854594 @default.
• W2887681716 cites W1998531275 @default.
• W2887681716 cites W1999026938 @default.
• W2887681716 cites W1999423603 @default.
• W2887681716 cites W2002135246 @default.
• W2887681716 cites W2003008313 @default.
• W2887681716 cites W2003661326 @default.
• W2887681716 cites W2004228931 @default.
• W2887681716 cites W2007124194 @default.
• W2887681716 cites W2008472492 @default.
• W2887681716 cites W2013842521 @default.
• W2887681716 cites W2014371597 @default.
• W2887681716 cites W2014421311 @default.
• W2887681716 cites W2016923150 @default.
• W2887681716 cites W2018969078 @default.
• W2887681716 cites W2019280950 @default.
• W2887681716 cites W2020307110 @default.
• W2887681716 cites W2022178469 @default.
• W2887681716 cites W2023007590 @default.
• W2887681716 cites W2030405347 @default.
• W2887681716 cites W2031042167 @default.
• W2887681716 cites W2031680195 @default.
• W2887681716 cites W2033779494 @default.
• W2887681716 cites W2034107517 @default.
• W2887681716 cites W2035801315 @default.
• W2887681716 cites W2039785758 @default.
• W2887681716 cites W2042042230 @default.
• W2887681716 cites W2047112161 @default.
• W2887681716 cites W2047718078 @default.
• W2887681716 cites W2050662812 @default.
• W2887681716 cites W2052709855 @default.
• W2887681716 cites W2056832894 @default.
• W2887681716 cites W2058151034 @default.
• W2887681716 cites W2058774107 @default.
• W2887681716 cites W2061111040 @default.
• W2887681716 cites W2064582094 @default.
• W2887681716 cites W2065121811 @default.
• W2887681716 cites W2065178883 @default.
• W2887681716 cites W2068274081 @default.
• W2887681716 cites W2076089369 @default.
• W2887681716 cites W2085823794 @default.
• W2887681716 cites W2086416049 @default.
• W2887681716 cites W2089835279 @default.
• W2887681716 cites W2090268048 @default.
• W2887681716 cites W2091583677 @default.
• W2887681716 cites W2098132847 @default.
• W2887681716 cites W2098272616 @default.
• W2887681716 cites W2101939433 @default.
• W2887681716 cites W2102349888 @default.
• W2887681716 cites W2111937809 @default.
• W2887681716 cites W2114202618 @default.
• W2887681716 cites W2120497414 @default.
• W2887681716 cites W2128561409 @default.
• W2887681716 cites W2134762554 @default.
• W2887681716 cites W2142709180 @default.
• W2887681716 cites W2143249342 @default.
• W2887681716 cites W2149665972 @default.
• W2887681716 cites W2162538983 @default.
• W2887681716 cites W2323043006 @default.
• W2887681716 cites W2345844428 @default.
• W2887681716 cites W2353494549 @default.
• W2887681716 cites W2364724678 @default.
• W2887681716 cites W2440035713 @default.
• W2887681716 cites W2467315040 @default.
• W2887681716 cites W2547403448 @default.
• W2887681716 cites W2588765164 @default.
• W2887681716 cites W2589017385 @default.
• W2887681716 cites W2607422829 @default.
• W2887681716 cites W2759148080 @default.
• W2887681716 cites W2789239266 @default.
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• W2887681716 doi "https://doi.org/10.3389/fmed.2018.00226" @default.
• W2887681716 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6102399" @default.
• W2887681716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30155467" @default.
• W2887681716 hasPublicationYear "2018" @default.
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