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• W2887730673 abstract "To compare outcomes of a nonvalved glaucoma drainage device (the Aurolab aqueous drainage device [AADI] with a valved glaucoma drainage device (the Ahmed glaucoma valve [AGV]) in refractory pediatric glaucoma. Retrospective interventional case series. One hundred sixteen eyes of 97 children with refractory pediatric glaucoma. Children (≤16 years) treated with drainage implants from January 2007 through December 2016 with a minimum follow-up of 6 months (operated by a single surgeon) were included. Success was defined as intraocular pressure (IOP) ≥6 mmHg or ≤21 mmHg (complete without antiglaucoma medications [AGMs] and qualified with AGM); repeat glaucoma surgery or loss of light perception was failure. Comparison of success rates and complications with AADI (350 mm2) and silicone AGV (models FP7 [182-mm2 surface area] and FP8 [102-mm2 surface area]) implantation. Outcomes of 116 eyes of 97 children (AADI, 36 eyes; AGV, 85 eyes; FP7, n = 14; FP8, n = 72) were analyzed. Median follow-up for AADI was 16.8 months (interquartile range [IQR], 11.7–24.5 months) and for AGV was 27 months (IQR, 15.3–52.3 months). Preoperative parameters (age, IOP, number of AGMs) were similar in both groups except number of previous nonglaucoma surgeries, which were significantly more in AADI (P = 0.05). Qualified success was similar (P = 0.81) in both groups, 91% and 88% at 1 year and 81% and 84% at 3 years with AADI and AGV, respectively. With AADI, the complete success was significantly more (41.8% vs.13.7%; P < 0.005). The postoperative mean IOP (12.6±5.5 mmHg vs. 17.6±6.8 mmHg; P = 0.001), median number of AGMs (1 [IQR, 0–2] vs. 2 [IQR, 1–3]; P < 0.001), and hypertensive phase (16.5% [n = 7] vs. 40% [n = 34]; P = 0.02) were significantly less in AADI compared with AGV. Transient complications (AADI, 30.5% [n = 11/36] vs. AGV, 21.1% [n = 18/85]; P = 0.26), sight-threatening complications (AADI, 13.9% [n = 5/36) vs. AGV, 7% [n = 6/85]; P = 0.22), and complications needing intervention (AADI, 19.4% [n = 7/36] vs. AGV, 14.1% [n = 12/85]; P = 0.46) were similar in both groups. In refractory pediatric glaucoma, both AGV and AADI showed similar qualified success and complication rates at 1 and 3 years. However, the AADI showed greater complete success, better IOP control, less need for AGM, and lesser incidence of an hypertensive phase." @default.
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• W2887730673 date "2018-11-01" @default.
• W2887730673 modified "2023-10-16" @default.
• W2887730673 title "Comparison of the New Low-Cost Nonvalved Glaucoma Drainage Device with Ahmed Glaucoma Valve in Refractory Pediatric Glaucoma in Indian Eyes" @default.
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• W2887730673 doi "https://doi.org/10.1016/j.ogla.2018.07.001" @default.
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