FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887763313> ?p ?o ?g. }

• W2887763313 endingPage "e0202319" @default.
• W2887763313 startingPage "e0202319" @default.
• W2887763313 abstract "Background Guideline-adherent prescribing for treatment of multiple risk factors in type 2 diabetes (T2D) patients is expected to improve clinical outcomes. However, the relationship to Health-Related Quality of Life (HRQoL) is not straightforward since guideline-adherent prescribing can increase medication burden. Objectives To test whether guideline-adherent prescribing and disease-specific medication burden are associated with HRQoL in patients with T2D. Methods Cross-sectional study including 1,044 T2D patients from the e-VitaDM/ZODIAC study in 2012 in the Netherlands. Data from the diabetes visit, such as laboratory and physical examinations and prescribed medication, and from two HRQoL questionnaires, the EuroQol 5 Dimensions 3 Levels (EQ5D-3L) and the World Health Organization Well-Being Index (WHO-5) were collected. Twenty indicators assessing prescribing of recommended glucose lowering drugs, statins, antihypertensives and renin-angiotensin-aldosterone system (RAAS)-inhibitors and potentially inappropriate drugs from a validated diabetes indicator set were included. Disease-specific medication burden was assessed using a modified version of the Medication Regimen Complexity Index (MRCI). Associations were tested with regression models, adjusting for age, gender, diabetes duration, comorbidity, body mass index and smoking. Results The mean MRCI was 7.1, the median EQ5D-3L-score was 0.86 and the mean WHO-5 score was 72. Seven indicators included too few patients and were excluded from the analysis. The remaining thirteen indicators focusing on recommended start, intensification, current and preferred use of glucose lowering drugs, statins, antihypertensives, RAAS inhibitors, and on inappropriate prescribing of glibenclamide and dual RAAS blockade were not significantly associated with HRQoL. Finally, also the MRCI was not associated with HRQoL. Conclusions We found no evidence for associations between guideline-adherent prescribing or disease-specific medication burden and HRQoL in T2D patients. This gives no rise to refrain from prescribing intensive treatment in T2D patients as recommended, but the interpretation of these results is limited by the cross-sectional study design and the selection of patients included in some indicators." @default.
• W2887763313 created "2018-08-22" @default.
• W2887763313 creator A5010367070 @default.
• W2887763313 creator A5029966007 @default.
• W2887763313 creator A5040803816 @default.
• W2887763313 creator A5054266211 @default.
• W2887763313 creator A5057615162 @default.
• W2887763313 creator A5073898736 @default.
• W2887763313 creator A5075995015 @default.
• W2887763313 creator A5080059067 @default.
• W2887763313 creator A5091882944 @default.
• W2887763313 date "2018-08-16" @default.
• W2887763313 modified "2023-10-03" @default.
• W2887763313 title "Is guideline-adherent prescribing associated with quality of life in patients with type 2 diabetes?" @default.
• W2887763313 cites W126464923 @default.
• W2887763313 cites W1966905392 @default.
• W2887763313 cites W1995695723 @default.
• W2887763313 cites W2022428376 @default.
• W2887763313 cites W2029347623 @default.
• W2887763313 cites W2037445719 @default.
• W2887763313 cites W2059803321 @default.
• W2887763313 cites W2083504039 @default.
• W2887763313 cites W2099517322 @default.
• W2887763313 cites W2101796845 @default.
• W2887763313 cites W2105055184 @default.
• W2887763313 cites W2108786753 @default.
• W2887763313 cites W2118332255 @default.
• W2887763313 cites W2120256142 @default.
• W2887763313 cites W2152289419 @default.
• W2887763313 cites W2153170671 @default.
• W2887763313 cites W2153836018 @default.
• W2887763313 cites W2170598895 @default.
• W2887763313 cites W2187077267 @default.
• W2887763313 cites W2197232693 @default.
• W2887763313 cites W2268973487 @default.
• W2887763313 cites W2286677751 @default.
• W2887763313 cites W2328754532 @default.
• W2887763313 cites W2565003460 @default.
• W2887763313 cites W2569244806 @default.
• W2887763313 cites W2611816807 @default.
• W2887763313 cites W4293003987 @default.
• W2887763313 cites W984807221 @default.
• W2887763313 doi "https://doi.org/10.1371/journal.pone.0202319" @default.
• W2887763313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6095535" @default.
• W2887763313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30114242" @default.
• W2887763313 hasPublicationYear "2018" @default.
• W2887763313 type Work @default.
• W2887763313 sameAs 2887763313 @default.
• W2887763313 citedByCount "4" @default.
• W2887763313 countsByYear W28877633132019 @default.
• W2887763313 countsByYear W28877633132022 @default.
• W2887763313 countsByYear W28877633132023 @default.
• W2887763313 crossrefType "journal-article" @default.
• W2887763313 hasAuthorship W2887763313A5010367070 @default.
• W2887763313 hasAuthorship W2887763313A5029966007 @default.
• W2887763313 hasAuthorship W2887763313A5040803816 @default.
• W2887763313 hasAuthorship W2887763313A5054266211 @default.
• W2887763313 hasAuthorship W2887763313A5057615162 @default.
• W2887763313 hasAuthorship W2887763313A5073898736 @default.
• W2887763313 hasAuthorship W2887763313A5075995015 @default.
• W2887763313 hasAuthorship W2887763313A5080059067 @default.
• W2887763313 hasAuthorship W2887763313A5091882944 @default.
• W2887763313 hasBestOaLocation W28877633131 @default.
• W2887763313 hasConcept C126322002 @default.
• W2887763313 hasConcept C134018914 @default.
• W2887763313 hasConcept C142052008 @default.
• W2887763313 hasConcept C142724271 @default.
• W2887763313 hasConcept C159110408 @default.
• W2887763313 hasConcept C1862650 @default.
• W2887763313 hasConcept C2777180221 @default.
• W2887763313 hasConcept C2779159551 @default.
• W2887763313 hasConcept C2779951463 @default.
• W2887763313 hasConcept C2780182762 @default.
• W2887763313 hasConcept C2780221984 @default.
• W2887763313 hasConcept C555293320 @default.
• W2887763313 hasConcept C71924100 @default.
• W2887763313 hasConceptScore W2887763313C126322002 @default.
• W2887763313 hasConceptScore W2887763313C134018914 @default.
• W2887763313 hasConceptScore W2887763313C142052008 @default.
• W2887763313 hasConceptScore W2887763313C142724271 @default.
• W2887763313 hasConceptScore W2887763313C159110408 @default.
• W2887763313 hasConceptScore W2887763313C1862650 @default.
• W2887763313 hasConceptScore W2887763313C2777180221 @default.
• W2887763313 hasConceptScore W2887763313C2779159551 @default.
• W2887763313 hasConceptScore W2887763313C2779951463 @default.
• W2887763313 hasConceptScore W2887763313C2780182762 @default.
• W2887763313 hasConceptScore W2887763313C2780221984 @default.
• W2887763313 hasConceptScore W2887763313C555293320 @default.
• W2887763313 hasConceptScore W2887763313C71924100 @default.
• W2887763313 hasFunder F4320321007 @default.
• W2887763313 hasIssue "8" @default.
• W2887763313 hasLocation W28877633131 @default.
• W2887763313 hasLocation W28877633132 @default.
• W2887763313 hasLocation W28877633133 @default.
• W2887763313 hasLocation W28877633134 @default.
• W2887763313 hasLocation W28877633135 @default.
• W2887763313 hasLocation W28877633136 @default.
• W2887763313 hasOpenAccess W2887763313 @default.

• next