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- W2887778638 abstract "In conventional DNA‐computation methods involving logic gate operations, the output molecules are detected and decoded mainly by gel electrophoresis or fluorescence measurements. To employ rapid and label‐free decoding, nanopore technology, an emerging methodology for single‐molecule detection or DNA sequencing, is proposed as a candidate for electrical and simple decoding of DNA computations. This review describes recent approaches to decoding DNA computation using label‐free and electrical nanopore measurements. Several attempts have been successful in DNA decoding with the nanopore either through enzymatic reactions or in water‐in‐oil droplets. Additionally, DNA computing combined with nanopore decoding has clinical applications, including microRNA detection for early diagnosis of cancers. Because this decoding methodology is still in development and not yet widely accepted, this review aims to inform the scientific community regarding usefulness." @default.
- W2887778638 created "2018-08-22" @default.
- W2887778638 creator A5033831861 @default.
- W2887778638 date "2018-08-31" @default.
- W2887778638 modified "2023-09-30" @default.
- W2887778638 title "Nanopore Decoding of Oligonucleotides in DNA Computing" @default.
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- W2887778638 doi "https://doi.org/10.1002/biot.201800091" @default.
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