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• W2887961980 abstract "We report herein a new ZIF-90-based PDT agent which was synthesized by in situ assembly of imidazole-2-carboxaldehyde (IcaH), Zn(NO3)2, and heavy atom iodine-attached Bodipy. The obtained 2I-BodipyPhNO2@ZIF-90 (1) host-guest photosensitive system featured low cytotoxicity, good biocompatibility, pH-driven selective cancer cell uptake and release, mitochondria targeting, and highly efficient pH-triggered 1O2 generation. Therefore, it can be used as a high-performing PDT agent to selectively kill tumor cells. In comparison to free 2I-BodipyPhNO2, 1 exhibits a much higher antitumor efficacy and selectivity, which was confirmed by in vitro cell experiments." @default.
• W2887961980 created "2018-08-22" @default.
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• W2887961980 date "2018-08-03" @default.
• W2887961980 modified "2023-10-18" @default.
• W2887961980 title "Diiodo-Bodipy-Encapsulated Nanoscale Metal–Organic Framework for pH-Driven Selective and Mitochondria Targeted Photodynamic Therapy" @default.
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• W2887961980 doi "https://doi.org/10.1021/acs.inorgchem.8b01316" @default.
• W2887961980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30074794" @default.
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