FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2887982374> ?p ?o ?g. }

• W2887982374 endingPage "396" @default.
• W2887982374 startingPage "383" @default.
• W2887982374 abstract "Summary: Chronic kidney disease (CKD) is a global public health burden. Dialysis is not only costly but may not be readily available in developing countries. Even in highly developed nations, many patients may prefer to defer or avoid dialysis. Thus, alternative options to dialysis therapy or to complement dialysis are needed urgently and are important objectives in CKD management that could have huge clinical and economic implications globally. The role of nutritional therapy as a strategy to slow CKD progression and uremia was discussed as early as the late 19th and early 20th century, but was only seriously explored in the 1970s. There is a revival of interest recently owing to encouraging data as well as the increase of precision medicine with an emphasis on a personalized approach to CKD management. Although part of the explanation for the inconclusive data may relate to variations in study design and dietary prescription, diversity in genetic make-up, variations in the non-nutritional management of CKD, intra-individual variations in responses to dietary and nondietary treatment, psychosocial factors, and dietary compliance issues, these all may contribute to the heterogeneous data and responses. This brings in the evolving concept of precision medicine, in which disease management should be tailored and individualized according not only to clinical manifestations but also to the genetic make-up and biologic responses to therapy, which may vary depending on genetic composition. Precision nutrition management also should take into account patient demographics, social, psychological, education, and compliance factors, which all may influence the therapeutic needs and responses to the nutritional therapy prescribed. In this review, we provide a novel concept of precision medicine in nutritional management in end-stage kidney disease with a transition to dialysis and propose how this may be the way forward for nutritional therapy in the CKD population. Summary: Chronic kidney disease (CKD) is a global public health burden. Dialysis is not only costly but may not be readily available in developing countries. Even in highly developed nations, many patients may prefer to defer or avoid dialysis. Thus, alternative options to dialysis therapy or to complement dialysis are needed urgently and are important objectives in CKD management that could have huge clinical and economic implications globally. The role of nutritional therapy as a strategy to slow CKD progression and uremia was discussed as early as the late 19th and early 20th century, but was only seriously explored in the 1970s. There is a revival of interest recently owing to encouraging data as well as the increase of precision medicine with an emphasis on a personalized approach to CKD management. Although part of the explanation for the inconclusive data may relate to variations in study design and dietary prescription, diversity in genetic make-up, variations in the non-nutritional management of CKD, intra-individual variations in responses to dietary and nondietary treatment, psychosocial factors, and dietary compliance issues, these all may contribute to the heterogeneous data and responses. This brings in the evolving concept of precision medicine, in which disease management should be tailored and individualized according not only to clinical manifestations but also to the genetic make-up and biologic responses to therapy, which may vary depending on genetic composition. Precision nutrition management also should take into account patient demographics, social, psychological, education, and compliance factors, which all may influence the therapeutic needs and responses to the nutritional therapy prescribed. In this review, we provide a novel concept of precision medicine in nutritional management in end-stage kidney disease with a transition to dialysis and propose how this may be the way forward for nutritional therapy in the CKD population." @default.
• W2887982374 created "2018-08-22" @default.
• W2887982374 creator A5005480103 @default.
• W2887982374 creator A5033022684 @default.
• W2887982374 creator A5047313234 @default.
• W2887982374 creator A5048145208 @default.
• W2887982374 creator A5050491175 @default.
• W2887982374 creator A5056946291 @default.
• W2887982374 creator A5074587712 @default.
• W2887982374 date "2018-07-01" @default.
• W2887982374 modified "2023-10-03" @default.
• W2887982374 title "Precision Medicine for Nutritional Management in End-Stage Kidney Disease and Transition to Dialysis" @default.
• W2887982374 cites W1972056828 @default.
• W2887982374 cites W1973663762 @default.
• W2887982374 cites W1985854311 @default.
• W2887982374 cites W1987605535 @default.
• W2887982374 cites W1989674465 @default.
• W2887982374 cites W1997396200 @default.
• W2887982374 cites W2001224650 @default.
• W2887982374 cites W2003748292 @default.
• W2887982374 cites W2011314613 @default.
• W2887982374 cites W2013073525 @default.
• W2887982374 cites W2014046186 @default.
• W2887982374 cites W2015668150 @default.
• W2887982374 cites W2023098366 @default.
• W2887982374 cites W2030940155 @default.
• W2887982374 cites W2034961623 @default.
• W2887982374 cites W2035718064 @default.
• W2887982374 cites W2049851390 @default.
• W2887982374 cites W2054015191 @default.
• W2887982374 cites W2056929656 @default.
• W2887982374 cites W2057002161 @default.
• W2887982374 cites W2065564412 @default.
• W2887982374 cites W2068772557 @default.
• W2887982374 cites W2070226792 @default.
• W2887982374 cites W2075065809 @default.
• W2887982374 cites W2082312748 @default.
• W2887982374 cites W2084473470 @default.
• W2887982374 cites W2086285483 @default.
• W2887982374 cites W2089054598 @default.
• W2887982374 cites W2090486027 @default.
• W2887982374 cites W2096694053 @default.
• W2887982374 cites W2097109426 @default.
• W2887982374 cites W2097399944 @default.
• W2887982374 cites W2100964992 @default.
• W2887982374 cites W2101164884 @default.
• W2887982374 cites W2101431807 @default.
• W2887982374 cites W2104774816 @default.
• W2887982374 cites W2105978370 @default.
• W2887982374 cites W2107616906 @default.
• W2887982374 cites W2113760558 @default.
• W2887982374 cites W2118493857 @default.
• W2887982374 cites W2122705341 @default.
• W2887982374 cites W2123376729 @default.
• W2887982374 cites W2124756039 @default.
• W2887982374 cites W2129559166 @default.
• W2887982374 cites W2131658070 @default.
• W2887982374 cites W2131843552 @default.
• W2887982374 cites W2132551391 @default.
• W2887982374 cites W2143447422 @default.
• W2887982374 cites W2149262429 @default.
• W2887982374 cites W2151768324 @default.
• W2887982374 cites W2152088948 @default.
• W2887982374 cites W2153031815 @default.
• W2887982374 cites W2156825907 @default.
• W2887982374 cites W2159944704 @default.
• W2887982374 cites W2161752722 @default.
• W2887982374 cites W2164249826 @default.
• W2887982374 cites W2165127899 @default.
• W2887982374 cites W2165945094 @default.
• W2887982374 cites W2166630818 @default.
• W2887982374 cites W2168234252 @default.
• W2887982374 cites W2168987491 @default.
• W2887982374 cites W2171540831 @default.
• W2887982374 cites W2260668761 @default.
• W2887982374 cites W2277103284 @default.
• W2887982374 cites W2291783238 @default.
• W2887982374 cites W2321986725 @default.
• W2887982374 cites W2330121013 @default.
• W2887982374 cites W2393703793 @default.
• W2887982374 cites W2549433900 @default.
• W2887982374 cites W2573136390 @default.
• W2887982374 cites W2577515884 @default.
• W2887982374 cites W2605486768 @default.
• W2887982374 cites W2674643896 @default.
• W2887982374 cites W2766047719 @default.
• W2887982374 cites W2766154018 @default.
• W2887982374 cites W2767784870 @default.
• W2887982374 cites W2771470498 @default.
• W2887982374 cites W2788611590 @default.
• W2887982374 cites W2884833833 @default.
• W2887982374 cites W37873869 @default.
• W2887982374 cites W4249918587 @default.
• W2887982374 doi "https://doi.org/10.1016/j.semnephrol.2018.05.008" @default.
• W2887982374 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30082058" @default.
• W2887982374 hasPublicationYear "2018" @default.
• W2887982374 type Work @default.
• W2887982374 sameAs 2887982374 @default.

• next