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- W2888068432 abstract "Introduction: Felodipine is used for the treatment of hypertension. In the present study a new stability-indicating RP-HPLC method has been established for the determination of Felodipine.in pharmaceutical dosage forms and the method was validated. Material and Methods: Shimadzu Model CBM-20A/20 Alite, UFLC system was used for the assay of Felodipine using a mixture of phosphate buffer (pH 7.0) and acetonitrile (20:80, v/v) as mobile phase with a flow rate of 1.2 ml/min (UV detection at 234 nm). Forced degradation studies were performed by exposing Felodipine to different stress conditions and the method was validated as per ICH guidelines. Results and Discussion: Felodipine is found to be more sensitive towards oxidative degradation. Conclusion: The proposed method is simple and economical and can be used for the determination of Felodipine in pharmaceutical formulations." @default.
- W2888068432 created "2018-08-31" @default.
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- W2888068432 date "2018-06-01" @default.
- W2888068432 modified "2023-09-24" @default.
- W2888068432 doi "https://doi.org/10.22377/ajp.v12i02.2400" @default.
- W2888068432 hasPublicationYear "2018" @default.
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