Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888111317> ?p ?o ?g. }
- W2888111317 abstract "The underlying mechanism of the effect of FTO genotype on body mass index (BMI) and body composition is unknown. The objective of the study was to investigate the association of FTO gene polymorphisms with anthropometric indices in adolescent boys after adjustments for dietary intake and physical activity. In this school-based study, we enrolled 123 male adolescents without extra weight and 110 male adolescents with body mass index (BMI) higher than + 1 Z-score. The DNA samples were genotyped for the FTO gene polymorphisms by DNA Sequencing. BMI and body composition were assessed using bioelectrical impedance analyzer scale. Association of the FTO polymorphisms with Weight, height, BMI, body fat percent and skeletal muscle percent were investigated. Data on potential confounders (calorie intake and physical activity) were collected through the use of pre-tested questionnaires. Adolescents with higher BMI and body fat percent and lower skeletal muscle percent were more likely to have a newly found haplotype of rs9930506, rs9930501 & rs9932754 (GGT) in the first intron of the FTO with complete linkage disequilibrium (LD) compared with those with the lower BMI (6.15;2.28–16.63), body fat percent (9.54;0.92–47.44) and higher skeletal muscle percent (9.26;1.85–46.38). This association was not changed after controlling for age. Additional adjustments for calorie intake and physical activity did not alter the association. A haplotype in the first intron of the FTO gene had a strong association with obesity indices in adolescent boys after adjustments for calorie intake and physical activity. It’s suggested that the FTO genotype exert its effects on adolescents’ anthropometric indices as haplotype and through mechanisms other than changes in calorie intake and expenditure. This paper reports the first phase of a comprehensive interventional study (Interactions of Genetics, lifestyle and anthropometrics study or IGLA study) and is retrospectively registered in the Iranian Registry of Clinical Trials as IRCT2016020925699N2. Date registered: April 24, 2016. ( http://www.irct.ir/searchresult.php?id=25699&number=2 )." @default.
- W2888111317 created "2018-08-31" @default.
- W2888111317 creator A5004895128 @default.
- W2888111317 creator A5020328315 @default.
- W2888111317 creator A5026547832 @default.
- W2888111317 creator A5033901210 @default.
- W2888111317 creator A5046234283 @default.
- W2888111317 creator A5057019241 @default.
- W2888111317 creator A5068797534 @default.
- W2888111317 creator A5074459549 @default.
- W2888111317 creator A5074659472 @default.
- W2888111317 creator A5082539583 @default.
- W2888111317 date "2018-08-20" @default.
- W2888111317 modified "2023-10-18" @default.
- W2888111317 title "A complete linkage disequilibrium in a haplotype of three SNPs in Fat Mass and Obesity associated (FTO) gene was strongly associated with anthropometric indices after controlling for calorie intake and physical activity" @default.
- W2888111317 cites W1976844911 @default.
- W2888111317 cites W1991838121 @default.
- W2888111317 cites W2002628700 @default.
- W2888111317 cites W2019389209 @default.
- W2888111317 cites W2034361573 @default.
- W2888111317 cites W2066669827 @default.
- W2888111317 cites W2078843839 @default.
- W2888111317 cites W2096640567 @default.
- W2888111317 cites W2097660065 @default.
- W2888111317 cites W2099786709 @default.
- W2888111317 cites W2110678911 @default.
- W2888111317 cites W2115953242 @default.
- W2888111317 cites W2120181458 @default.
- W2888111317 cites W2121798080 @default.
- W2888111317 cites W2123005049 @default.
- W2888111317 cites W2124185446 @default.
- W2888111317 cites W2134487705 @default.
- W2888111317 cites W2141644255 @default.
- W2888111317 cites W2146776863 @default.
- W2888111317 cites W2148924243 @default.
- W2888111317 cites W2156039962 @default.
- W2888111317 cites W2158069164 @default.
- W2888111317 cites W2162072565 @default.
- W2888111317 cites W2166431807 @default.
- W2888111317 cites W2169494000 @default.
- W2888111317 cites W2170575553 @default.
- W2888111317 cites W2182680246 @default.
- W2888111317 cites W2227839524 @default.
- W2888111317 cites W2580407390 @default.
- W2888111317 cites W2587328082 @default.
- W2888111317 cites W2946553280 @default.
- W2888111317 doi "https://doi.org/10.1186/s12881-018-0664-z" @default.
- W2888111317 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6102807" @default.
- W2888111317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30126381" @default.
- W2888111317 hasPublicationYear "2018" @default.
- W2888111317 type Work @default.
- W2888111317 sameAs 2888111317 @default.
- W2888111317 citedByCount "8" @default.
- W2888111317 countsByYear W28881113172019 @default.
- W2888111317 countsByYear W28881113172020 @default.
- W2888111317 countsByYear W28881113172021 @default.
- W2888111317 countsByYear W28881113172022 @default.
- W2888111317 countsByYear W28881113172023 @default.
- W2888111317 crossrefType "journal-article" @default.
- W2888111317 hasAuthorship W2888111317A5004895128 @default.
- W2888111317 hasAuthorship W2888111317A5020328315 @default.
- W2888111317 hasAuthorship W2888111317A5026547832 @default.
- W2888111317 hasAuthorship W2888111317A5033901210 @default.
- W2888111317 hasAuthorship W2888111317A5046234283 @default.
- W2888111317 hasAuthorship W2888111317A5057019241 @default.
- W2888111317 hasAuthorship W2888111317A5068797534 @default.
- W2888111317 hasAuthorship W2888111317A5074459549 @default.
- W2888111317 hasAuthorship W2888111317A5074659472 @default.
- W2888111317 hasAuthorship W2888111317A5082539583 @default.
- W2888111317 hasBestOaLocation W28881113171 @default.
- W2888111317 hasConcept C104317684 @default.
- W2888111317 hasConcept C126322002 @default.
- W2888111317 hasConcept C134018914 @default.
- W2888111317 hasConcept C135763542 @default.
- W2888111317 hasConcept C153209595 @default.
- W2888111317 hasConcept C197754878 @default.
- W2888111317 hasConcept C2780005051 @default.
- W2888111317 hasConcept C2780221984 @default.
- W2888111317 hasConcept C2780428817 @default.
- W2888111317 hasConcept C33872192 @default.
- W2888111317 hasConcept C35605836 @default.
- W2888111317 hasConcept C511355011 @default.
- W2888111317 hasConcept C54355233 @default.
- W2888111317 hasConcept C61427482 @default.
- W2888111317 hasConcept C71924100 @default.
- W2888111317 hasConcept C77350462 @default.
- W2888111317 hasConcept C86803240 @default.
- W2888111317 hasConceptScore W2888111317C104317684 @default.
- W2888111317 hasConceptScore W2888111317C126322002 @default.
- W2888111317 hasConceptScore W2888111317C134018914 @default.
- W2888111317 hasConceptScore W2888111317C135763542 @default.
- W2888111317 hasConceptScore W2888111317C153209595 @default.
- W2888111317 hasConceptScore W2888111317C197754878 @default.
- W2888111317 hasConceptScore W2888111317C2780005051 @default.
- W2888111317 hasConceptScore W2888111317C2780221984 @default.
- W2888111317 hasConceptScore W2888111317C2780428817 @default.
- W2888111317 hasConceptScore W2888111317C33872192 @default.
- W2888111317 hasConceptScore W2888111317C35605836 @default.
- W2888111317 hasConceptScore W2888111317C511355011 @default.
- W2888111317 hasConceptScore W2888111317C54355233 @default.