FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888333702> ?p ?o ?g. }

• W2888333702 endingPage "134" @default.
• W2888333702 startingPage "128" @default.
• W2888333702 abstract "Background The relationship between walking disability in multiple sclerosis (MS) patients and their macro- and microstructural MRI-derived measures still remains unclear. Objective To assess the correlations between walking disability and MRI-derived lesion, atrophy, and microstructural/axonal integrity outcomes. Methods Seventy-one (71) MS patients were clinically examined, the expanded timed get-up and go (ETGUG), and timed 25-foot walk (T25FW) tests were assessed. Additionally, the Symbol Digit Modalities Test (SDMT) was obtained. Normalized brain (NBV), gray matter (GMV), white matter (WMV), cortex (CV), and deep GM (DGM) volumes, as well as lesion volumes (LV) and diffusion tensor imaging (DTI) scalar maps of fractional anisotropy, mean diffusivity, radial diffusivity, and axial diffusivity were calculated. Spearman correlation, partial correlation and stepwise regression analyses were performed. Results T25FW and ETGUG were associated with T2-LV (p < .001), global (NBV, p < .001), tissue-specific (GMV and CV, p < .001) and regional (DGM p < .001; and thalamus p < .001) volumes. The ETGUG remained correlated with T1-LV, GMV, CV and total DGM volume (all p < .001) after age, sex, and disease duration adjustment. The WMV was not associated with walking disability. Similarly, DTI measures did not show significant association with the walking tests. The regression analysis outlined DMG volume as best predictor of T25FW (Adj R2 = 0.231, standardized β = −0.435, and p = .001), and CV for ETGUG (Adj R2 = 0.176, standardized β = −0.417, and p = .004). SDMT was associated with both T25FW (p = .004) and ETGUG (p = .013). Conclusion Despite the low disability levels, walking as measured by T25FW and ETGUG, is largely explained by the loss of cortical and nuclei specific GM volumes." @default.
• W2888333702 created "2018-08-31" @default.
• W2888333702 creator A5005341542 @default.
• W2888333702 creator A5029686204 @default.
• W2888333702 creator A5033147621 @default.
• W2888333702 creator A5033859874 @default.
• W2888333702 creator A5034998428 @default.
• W2888333702 creator A5038453962 @default.
• W2888333702 creator A5041234325 @default.
• W2888333702 creator A5049031620 @default.
• W2888333702 creator A5055648634 @default.
• W2888333702 creator A5058745536 @default.
• W2888333702 creator A5075596287 @default.
• W2888333702 creator A5079130521 @default.
• W2888333702 date "2018-10-01" @default.
• W2888333702 modified "2023-10-17" @default.
• W2888333702 title "Walking disability measures in multiple sclerosis patients: Correlations with MRI-derived global and microstructural damage" @default.
• W2888333702 cites W105766518 @default.
• W2888333702 cites W1497872038 @default.
• W2888333702 cites W16535422 @default.
• W2888333702 cites W172925500 @default.
• W2888333702 cites W1998455368 @default.
• W2888333702 cites W2019125376 @default.
• W2888333702 cites W2028942474 @default.
• W2888333702 cites W2046748764 @default.
• W2888333702 cites W2055250060 @default.
• W2888333702 cites W2057434762 @default.
• W2888333702 cites W2083869326 @default.
• W2888333702 cites W2087671528 @default.
• W2888333702 cites W2089940272 @default.
• W2888333702 cites W2101251292 @default.
• W2888333702 cites W2103867627 @default.
• W2888333702 cites W2104878804 @default.
• W2888333702 cites W2112165124 @default.
• W2888333702 cites W2116136260 @default.
• W2888333702 cites W2119408292 @default.
• W2888333702 cites W2132144289 @default.
• W2888333702 cites W2143567192 @default.
• W2888333702 cites W2145481931 @default.
• W2888333702 cites W2145583517 @default.
• W2888333702 cites W2153073862 @default.
• W2888333702 cites W2261643369 @default.
• W2888333702 cites W2273220492 @default.
• W2888333702 cites W2277481803 @default.
• W2888333702 cites W231524405 @default.
• W2888333702 cites W2337612449 @default.
• W2888333702 cites W2339972492 @default.
• W2888333702 cites W2415334274 @default.
• W2888333702 cites W2479632750 @default.
• W2888333702 cites W2548632358 @default.
• W2888333702 cites W2586165015 @default.
• W2888333702 cites W2588292672 @default.
• W2888333702 cites W2589232523 @default.
• W2888333702 cites W2594320863 @default.
• W2888333702 cites W2600662623 @default.
• W2888333702 cites W2615889936 @default.
• W2888333702 cites W2755110924 @default.
• W2888333702 cites W2782105896 @default.
• W2888333702 cites W2782264775 @default.
• W2888333702 cites W2791620262 @default.
• W2888333702 cites W2806729167 @default.
• W2888333702 cites W2879818332 @default.
• W2888333702 doi "https://doi.org/10.1016/j.jns.2018.08.020" @default.
• W2888333702 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30165291" @default.
• W2888333702 hasPublicationYear "2018" @default.
• W2888333702 type Work @default.
• W2888333702 sameAs 2888333702 @default.
• W2888333702 citedByCount "25" @default.
• W2888333702 countsByYear W28883337022019 @default.
• W2888333702 countsByYear W28883337022020 @default.
• W2888333702 countsByYear W28883337022021 @default.
• W2888333702 countsByYear W28883337022022 @default.
• W2888333702 countsByYear W28883337022023 @default.
• W2888333702 crossrefType "journal-article" @default.
• W2888333702 hasAuthorship W2888333702A5005341542 @default.
• W2888333702 hasAuthorship W2888333702A5029686204 @default.
• W2888333702 hasAuthorship W2888333702A5033147621 @default.
• W2888333702 hasAuthorship W2888333702A5033859874 @default.
• W2888333702 hasAuthorship W2888333702A5034998428 @default.
• W2888333702 hasAuthorship W2888333702A5038453962 @default.
• W2888333702 hasAuthorship W2888333702A5041234325 @default.
• W2888333702 hasAuthorship W2888333702A5049031620 @default.
• W2888333702 hasAuthorship W2888333702A5055648634 @default.
• W2888333702 hasAuthorship W2888333702A5058745536 @default.
• W2888333702 hasAuthorship W2888333702A5075596287 @default.
• W2888333702 hasAuthorship W2888333702A5079130521 @default.
• W2888333702 hasConcept C118552586 @default.
• W2888333702 hasConcept C126322002 @default.
• W2888333702 hasConcept C126838900 @default.
• W2888333702 hasConcept C143409427 @default.
• W2888333702 hasConcept C149550507 @default.
• W2888333702 hasConcept C15744967 @default.
• W2888333702 hasConcept C164705383 @default.
• W2888333702 hasConcept C169760540 @default.
• W2888333702 hasConcept C1862650 @default.
• W2888333702 hasConcept C2779246727 @default.
• W2888333702 hasConcept C2780640218 @default.
• W2888333702 hasConcept C2781192897 @default.

• next