Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888366953> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2888366953 endingPage "97" @default.
- W2888366953 startingPage "91" @default.
- W2888366953 abstract "Three Tesla multiparametric magnetic resonance imaging with PI-RADS™ (Prostate Imaging Reporting and Data System) version 2 scoring is a common tool in prostate cancer diagnosis which informs the likelihood of a cancerous lesion. We investigated whether PI-RADS version 2 also predicts adverse pathology features mainly in patients with biopsy Gleason score 3 + 4 disease.We reviewed the records of 326 consecutive men with a preoperative template and/or magnetic resonance imaging-ultrasound fusion biopsy Gleason score of 6-7 from a prospectively maintained database of men who underwent robotic radical prostatectomy. The primary analysis was done in patients with biopsy Gleason score 3 + 4 to assess the primary outcome of adverse pathology features on univariate and multivariate logistic regression. The secondary outcome was biochemical recurrence-free survival using the Kaplan-Meier method. Similar analysis was done in patients with a biopsy Gleason score of 6-7.Of men with Gleason score 3 + 4 findings 27%, 15%, 36% and 23% showed a PI-RADS version 2 score of 0-2, 3, 4 and 5, respectively. On univariate analysis PI-RADS version 2 category 5 predicted adverse pathology features vs categories 0-2 (OR 10.7, 95% CI 3.7-31, p ≤0.001). On multivariate analysis the PI-RADS version 2 category 5 was associated with adverse pathology when adjusting for preoperative magnetic resonance imaging targeted biopsy (OR 11.4, 95% CI 3.7-35, p ≤0.0001). In men with a targeted biopsy Gleason score of 3 + 4 prostate cancer PI-RADS version 2 category 5 was associated with adverse pathology (OR 14.7, 95% CI 1.5-146.9, p = 0.02). Of men with biopsy Gleason score 3 + 4 disease 92% and 58% with a PI-RADS version 2 score of 4 and 5, respectively, had 2-year biochemical recurrence-free survival.A PI-RADS version 2 category 5 lesion in patients with a biopsy Gleason score 3 + 4 lesion predicted adverse pathology features and biochemical recurrence-free survival. These findings suggest that preoperative 3 Tesla multiparametric magnetic resonance imaging may serve as a prognostic marker of treatment outcomes independently of biopsy Gleason score or biopsy type." @default.
- W2888366953 created "2018-08-31" @default.
- W2888366953 creator A5009700206 @default.
- W2888366953 creator A5013166503 @default.
- W2888366953 creator A5016291944 @default.
- W2888366953 creator A5025876997 @default.
- W2888366953 creator A5040802277 @default.
- W2888366953 creator A5058617146 @default.
- W2888366953 creator A5064290590 @default.
- W2888366953 creator A5070990818 @default.
- W2888366953 creator A5087591232 @default.
- W2888366953 date "2019-01-01" @default.
- W2888366953 modified "2023-10-18" @default.
- W2888366953 title "PI-RADS Version 2 Category on 3 Tesla Multiparametric Prostate Magnetic Resonance Imaging Predicts Oncologic Outcomes in Gleason 3 + 4 Prostate Cancer on Biopsy" @default.
- W2888366953 doi "https://doi.org/10.1016/j.juro.2018.08.043" @default.
- W2888366953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30577397" @default.
- W2888366953 hasPublicationYear "2019" @default.
- W2888366953 type Work @default.
- W2888366953 sameAs 2888366953 @default.
- W2888366953 citedByCount "15" @default.
- W2888366953 countsByYear W28883669532019 @default.
- W2888366953 countsByYear W28883669532020 @default.
- W2888366953 countsByYear W28883669532021 @default.
- W2888366953 countsByYear W28883669532023 @default.
- W2888366953 crossrefType "journal-article" @default.
- W2888366953 hasAuthorship W2888366953A5009700206 @default.
- W2888366953 hasAuthorship W2888366953A5013166503 @default.
- W2888366953 hasAuthorship W2888366953A5016291944 @default.
- W2888366953 hasAuthorship W2888366953A5025876997 @default.
- W2888366953 hasAuthorship W2888366953A5040802277 @default.
- W2888366953 hasAuthorship W2888366953A5058617146 @default.
- W2888366953 hasAuthorship W2888366953A5064290590 @default.
- W2888366953 hasAuthorship W2888366953A5070990818 @default.
- W2888366953 hasAuthorship W2888366953A5087591232 @default.
- W2888366953 hasConcept C121608353 @default.
- W2888366953 hasConcept C126322002 @default.
- W2888366953 hasConcept C126838900 @default.
- W2888366953 hasConcept C126894567 @default.
- W2888366953 hasConcept C143409427 @default.
- W2888366953 hasConcept C144301174 @default.
- W2888366953 hasConcept C2775934546 @default.
- W2888366953 hasConcept C2776235491 @default.
- W2888366953 hasConcept C2779466945 @default.
- W2888366953 hasConcept C2780192828 @default.
- W2888366953 hasConcept C2781217009 @default.
- W2888366953 hasConcept C38180746 @default.
- W2888366953 hasConcept C71924100 @default.
- W2888366953 hasConceptScore W2888366953C121608353 @default.
- W2888366953 hasConceptScore W2888366953C126322002 @default.
- W2888366953 hasConceptScore W2888366953C126838900 @default.
- W2888366953 hasConceptScore W2888366953C126894567 @default.
- W2888366953 hasConceptScore W2888366953C143409427 @default.
- W2888366953 hasConceptScore W2888366953C144301174 @default.
- W2888366953 hasConceptScore W2888366953C2775934546 @default.
- W2888366953 hasConceptScore W2888366953C2776235491 @default.
- W2888366953 hasConceptScore W2888366953C2779466945 @default.
- W2888366953 hasConceptScore W2888366953C2780192828 @default.
- W2888366953 hasConceptScore W2888366953C2781217009 @default.
- W2888366953 hasConceptScore W2888366953C38180746 @default.
- W2888366953 hasConceptScore W2888366953C71924100 @default.
- W2888366953 hasIssue "1" @default.
- W2888366953 hasLocation W28883669531 @default.
- W2888366953 hasLocation W28883669532 @default.
- W2888366953 hasOpenAccess W2888366953 @default.
- W2888366953 hasPrimaryLocation W28883669531 @default.
- W2888366953 hasRelatedWork W1530684645 @default.
- W2888366953 hasRelatedWork W1725314107 @default.
- W2888366953 hasRelatedWork W1884231116 @default.
- W2888366953 hasRelatedWork W1979374145 @default.
- W2888366953 hasRelatedWork W2102167265 @default.
- W2888366953 hasRelatedWork W2148869351 @default.
- W2888366953 hasRelatedWork W2151006016 @default.
- W2888366953 hasRelatedWork W2409990396 @default.
- W2888366953 hasRelatedWork W2566665866 @default.
- W2888366953 hasRelatedWork W3197418554 @default.
- W2888366953 hasVolume "201" @default.
- W2888366953 isParatext "false" @default.
- W2888366953 isRetracted "false" @default.
- W2888366953 magId "2888366953" @default.
- W2888366953 workType "article" @default.