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- W2888367024 abstract "Although the histologically diverse classification of salivary gland tumors can be successfully applied to the epithelial lacrimal gland neoplasms, it is not clear whether the molecular makeup differs between these two different tumor types. Adenocarcinomas have known to have driver mutations in non-small cell lung cancer, however, besides HER2 expression not much is known regarding molecular drivers in lacrimal tumors. Androgen receptor (AR) expression and deprivation combined with checkpoint inhibition (CPI) have not been described before in lacrimal gland adenocarcinoma. To our knowledge, this is the first case report describing a prolonged response to CPI and AR inhibitors." @default.
- W2888367024 created "2018-08-31" @default.
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- W2888367024 date "2018-08-25" @default.
- W2888367024 modified "2023-09-26" @default.
- W2888367024 title "Lacrimal gland adenocarcinoma responding to checkpoint inhibition and androgen deprivation" @default.
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- W2888367024 doi "https://doi.org/10.1093/omcr/omy066" @default.
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