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- W2888429413 abstract "With an increasing focus on patient-centric delivery of care and growing financial constraints on healthcare, several common oncology chemotherapy regimens traditionally administered in the inpatient setting have been considered and evaluated in the ambulatory care setting. Although most solid malignancies are now safely treated with chemotherapy in the ambulatory care setting, there are several common regimens for treating hematologic malignancies that have been historically viewed as being exclusively inpatient regimens. There are various factors that make the delivery of certain regimens in the inpatient setting preferable, such as issues of frequency and timing and the need for continuous infusion of certain drugs. Due to concern for patient monitoring and potentially emergent toxicities, such as those seen with use of high-dose ifosfamide or high-dose cytarabine (HiDAC), these regimens have been almost exclusively given in the inpatient setting.1,2 To increase patient satisfaction, improve access to therapy, and address a continuous reduction in resources manifested as lower inpatient bed availability or increased inpatient care costs, an increasing trend toward delivering these regimens in the outpatient setting has been observed. Outpatient chemotherapy administration has several advantages, such as patient convenience, ease of drug administration, and medication delivery in a familiar environment that facilitates patient comfort and well-being.3 Advances in supportive care for treatment-related complications such as chemotherapy-induced nausea and vomiting have played a critical role in shifting administration of highly emetogenic regimens (e.g., high-dose cisplatin) to the outpatient setting.4,5 Additionally, continuous-infusion pumps have enabled safe administration of a variety of chemotherapy regimens, in particular fluorouracil-containing regimens for solid tumors, without the need for hospitalization.6" @default.
- W2888429413 created "2018-08-31" @default.
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- W2888429413 date "2018-11-15" @default.
- W2888429413 modified "2023-10-18" @default.
- W2888429413 title "Transitioning historically inpatient chemotherapy regimens for hematologic malignancies to the ambulatory care setting" @default.
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- W2888429413 doi "https://doi.org/10.2146/ajhp180060" @default.
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