Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888552017> ?p ?o ?g. }
- W2888552017 endingPage "14" @default.
- W2888552017 startingPage "14" @default.
- W2888552017 abstract "In the body, mesenchymal progenitor cells are subjected to a substantial amount external force from different mechanical stresses, each potentially influences their behaviour and maintenance differentially. Tensile stress, or compression loading are just two of these forces, and here we examine the role of cyclical or dynamic mechanical loading on progenitor cell proliferation and differentiation, as well as on other cellular processes including cell morphology, apoptosis and matrix mineralisation. Moreover, we also examine how mechanical stretch can be used to optimise and ready biomaterials before their implantation, and examine the role of the circadian rhythm, the body’s innate time keeping system, on biomaterial delivery and acceptance. Finally, we also investigate the effect of mechanical stretch on the circadian rhythm of progenitor cells, as research suggests that mechanical stimulation may be sufficient in itself to synchronise the circadian rhythm of human adult progenitor cells alone, and has also been linked to progenitor cell function. If proven correct, this could offer a novel, non-intrusive method by which human adult progenitor cells may be activated or preconditioned, being readied for differentiation, so that they may be more successfully integrated within a host body, thereby improving tissue engineering techniques and the efficacy of cellular therapies." @default.
- W2888552017 created "2018-08-31" @default.
- W2888552017 creator A5015647527 @default.
- W2888552017 creator A5036006130 @default.
- W2888552017 creator A5076755921 @default.
- W2888552017 date "2018-08-24" @default.
- W2888552017 modified "2023-09-26" @default.
- W2888552017 title "Mechanical stretch and chronotherapeutic techniques for progenitor cell transplantation and biomaterials" @default.
- W2888552017 cites W108709636 @default.
- W2888552017 cites W1556212925 @default.
- W2888552017 cites W1595842219 @default.
- W2888552017 cites W1691737563 @default.
- W2888552017 cites W1968354809 @default.
- W2888552017 cites W1973196934 @default.
- W2888552017 cites W1973788573 @default.
- W2888552017 cites W1975002113 @default.
- W2888552017 cites W1975863863 @default.
- W2888552017 cites W1980867815 @default.
- W2888552017 cites W1983188704 @default.
- W2888552017 cites W1987913622 @default.
- W2888552017 cites W1991096907 @default.
- W2888552017 cites W2003302378 @default.
- W2888552017 cites W2004817997 @default.
- W2888552017 cites W2009132775 @default.
- W2888552017 cites W2009276350 @default.
- W2888552017 cites W2015703121 @default.
- W2888552017 cites W2016673036 @default.
- W2888552017 cites W2019101681 @default.
- W2888552017 cites W2019257051 @default.
- W2888552017 cites W2020451860 @default.
- W2888552017 cites W2023136127 @default.
- W2888552017 cites W2032269766 @default.
- W2888552017 cites W2037744155 @default.
- W2888552017 cites W2042767306 @default.
- W2888552017 cites W2050918140 @default.
- W2888552017 cites W2052198334 @default.
- W2888552017 cites W2054513544 @default.
- W2888552017 cites W2057982950 @default.
- W2888552017 cites W2061768724 @default.
- W2888552017 cites W2067108199 @default.
- W2888552017 cites W2067542470 @default.
- W2888552017 cites W2070317775 @default.
- W2888552017 cites W2077311918 @default.
- W2888552017 cites W2080319666 @default.
- W2888552017 cites W2081791895 @default.
- W2888552017 cites W2091580391 @default.
- W2888552017 cites W2092658506 @default.
- W2888552017 cites W2093505571 @default.
- W2888552017 cites W2104440688 @default.
- W2888552017 cites W2112376443 @default.
- W2888552017 cites W2114547937 @default.
- W2888552017 cites W2117513690 @default.
- W2888552017 cites W2137252071 @default.
- W2888552017 cites W2140729200 @default.
- W2888552017 cites W2144421573 @default.
- W2888552017 cites W2146635117 @default.
- W2888552017 cites W2157022909 @default.
- W2888552017 cites W2159999899 @default.
- W2888552017 cites W2302167425 @default.
- W2888552017 cites W2581072839 @default.
- W2888552017 cites W2588722843 @default.
- W2888552017 cites W2724599949 @default.
- W2888552017 cites W2747441327 @default.
- W2888552017 cites W4249736061 @default.
- W2888552017 cites W4385619632 @default.
- W2888552017 cites W47389156 @default.
- W2888552017 cites W73624576 @default.
- W2888552017 doi "https://doi.org/10.1051/bmdcn/2018080314" @default.
- W2888552017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6108224" @default.
- W2888552017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30141401" @default.
- W2888552017 hasPublicationYear "2018" @default.
- W2888552017 type Work @default.
- W2888552017 sameAs 2888552017 @default.
- W2888552017 citedByCount "8" @default.
- W2888552017 countsByYear W28885520172018 @default.
- W2888552017 countsByYear W28885520172019 @default.
- W2888552017 countsByYear W28885520172021 @default.
- W2888552017 countsByYear W28885520172022 @default.
- W2888552017 countsByYear W28885520172023 @default.
- W2888552017 crossrefType "journal-article" @default.
- W2888552017 hasAuthorship W2888552017A5015647527 @default.
- W2888552017 hasAuthorship W2888552017A5036006130 @default.
- W2888552017 hasAuthorship W2888552017A5076755921 @default.
- W2888552017 hasBestOaLocation W28885520171 @default.
- W2888552017 hasConcept C136229726 @default.
- W2888552017 hasConcept C141071460 @default.
- W2888552017 hasConcept C201750760 @default.
- W2888552017 hasConcept C28328180 @default.
- W2888552017 hasConcept C2911091166 @default.
- W2888552017 hasConcept C71924100 @default.
- W2888552017 hasConcept C86803240 @default.
- W2888552017 hasConcept C95444343 @default.
- W2888552017 hasConceptScore W2888552017C136229726 @default.
- W2888552017 hasConceptScore W2888552017C141071460 @default.
- W2888552017 hasConceptScore W2888552017C201750760 @default.
- W2888552017 hasConceptScore W2888552017C28328180 @default.
- W2888552017 hasConceptScore W2888552017C2911091166 @default.
- W2888552017 hasConceptScore W2888552017C71924100 @default.