Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888578377> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2888578377 endingPage "e11786" @default.
- W2888578377 startingPage "e11786" @default.
- W2888578377 abstract "To investigate the effect of neoadjuvant chemotherapy in patients with advanced vulvar cancer and to provide references for clinical treatment.Clinical and pathological data of 12 patients with advanced vulvar carcinoma were collected. The response and operability rates, adverse effects, and prognosis of neoadjuvant chemotherapy were retrospectively analyzed.The mean patient age was 45.8 (range 26-69) years. Among 12 patients, 9 underwent treatment with bleomycin and cisplatin with or without vincristine. The overall response rate was 67%. Five patients (56%) experienced grade 1 or 2 bone marrow suppression or gastrointestinal reactions. Seven patients (78%) underwent radical surgery. The mean overall survival time was 34.1 (range 3-69) months, the mean progression free survival time was 26 (range 3-69) months, and the 1-year survival rate was 83%. The other 3 patients received combined paclitaxel and cisplatin treatment. The overall response rate was 67%. All 3 patients (100%) experienced grade 2 hair loss or anemia and 2 of them (67%) underwent radical vulvectomy. The mean overall survival time was 11.7 (range 5-15) months, the mean progression free survival time was 7.7 (range 3-15) months and the 1-year survival rate was 100%. Time to overall survival and progression free survival were not significantly different between the 2 groups (P = .46 and P = .39).Owing to their high overall response rate and tolerable adverse effects, either bleomycin-cisplatin-based or paclitaxel-based neoadjuvant chemotherapy regimen can be considered a therapeutic option for advanced vulvar cancer." @default.
- W2888578377 created "2018-08-31" @default.
- W2888578377 creator A5001705168 @default.
- W2888578377 creator A5023963387 @default.
- W2888578377 creator A5024637745 @default.
- W2888578377 creator A5026950991 @default.
- W2888578377 creator A5090765880 @default.
- W2888578377 creator A5090964683 @default.
- W2888578377 date "2018-08-01" @default.
- W2888578377 modified "2023-09-25" @default.
- W2888578377 title "Clinical analysis of neoadjuvant chemotherapy in patients with advanced vulvar cancer" @default.
- W2888578377 cites W1977198608 @default.
- W2888578377 cites W1978163677 @default.
- W2888578377 cites W2012385586 @default.
- W2888578377 cites W2019607817 @default.
- W2888578377 cites W2034822990 @default.
- W2888578377 cites W2037951950 @default.
- W2888578377 cites W2047370015 @default.
- W2888578377 cites W2049536465 @default.
- W2888578377 cites W2057300416 @default.
- W2888578377 cites W2075415215 @default.
- W2888578377 cites W2081423951 @default.
- W2888578377 cites W2095148478 @default.
- W2888578377 cites W2098037595 @default.
- W2888578377 cites W2410310668 @default.
- W2888578377 cites W2551974662 @default.
- W2888578377 cites W2566050889 @default.
- W2888578377 cites W2569543447 @default.
- W2888578377 cites W2570618306 @default.
- W2888578377 cites W3174865415 @default.
- W2888578377 cites W92798296 @default.
- W2888578377 doi "https://doi.org/10.1097/md.0000000000011786" @default.
- W2888578377 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6113009" @default.
- W2888578377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30142764" @default.
- W2888578377 hasPublicationYear "2018" @default.
- W2888578377 type Work @default.
- W2888578377 sameAs 2888578377 @default.
- W2888578377 citedByCount "8" @default.
- W2888578377 countsByYear W28885783772020 @default.
- W2888578377 countsByYear W28885783772021 @default.
- W2888578377 countsByYear W28885783772022 @default.
- W2888578377 countsByYear W28885783772023 @default.
- W2888578377 crossrefType "journal-article" @default.
- W2888578377 hasAuthorship W2888578377A5001705168 @default.
- W2888578377 hasAuthorship W2888578377A5023963387 @default.
- W2888578377 hasAuthorship W2888578377A5024637745 @default.
- W2888578377 hasAuthorship W2888578377A5026950991 @default.
- W2888578377 hasAuthorship W2888578377A5090765880 @default.
- W2888578377 hasAuthorship W2888578377A5090964683 @default.
- W2888578377 hasBestOaLocation W28885783771 @default.
- W2888578377 hasConcept C126322002 @default.
- W2888578377 hasConcept C141071460 @default.
- W2888578377 hasConcept C143998085 @default.
- W2888578377 hasConcept C197934379 @default.
- W2888578377 hasConcept C2776283816 @default.
- W2888578377 hasConcept C2776581026 @default.
- W2888578377 hasConcept C2776694085 @default.
- W2888578377 hasConcept C2778248108 @default.
- W2888578377 hasConcept C2781413609 @default.
- W2888578377 hasConcept C71924100 @default.
- W2888578377 hasConceptScore W2888578377C126322002 @default.
- W2888578377 hasConceptScore W2888578377C141071460 @default.
- W2888578377 hasConceptScore W2888578377C143998085 @default.
- W2888578377 hasConceptScore W2888578377C197934379 @default.
- W2888578377 hasConceptScore W2888578377C2776283816 @default.
- W2888578377 hasConceptScore W2888578377C2776581026 @default.
- W2888578377 hasConceptScore W2888578377C2776694085 @default.
- W2888578377 hasConceptScore W2888578377C2778248108 @default.
- W2888578377 hasConceptScore W2888578377C2781413609 @default.
- W2888578377 hasConceptScore W2888578377C71924100 @default.
- W2888578377 hasIssue "34" @default.
- W2888578377 hasLocation W28885783771 @default.
- W2888578377 hasLocation W28885783772 @default.
- W2888578377 hasLocation W28885783773 @default.
- W2888578377 hasLocation W28885783774 @default.
- W2888578377 hasOpenAccess W2888578377 @default.
- W2888578377 hasPrimaryLocation W28885783771 @default.
- W2888578377 hasRelatedWork W1984282923 @default.
- W2888578377 hasRelatedWork W2091720821 @default.
- W2888578377 hasRelatedWork W2352942126 @default.
- W2888578377 hasRelatedWork W2363788204 @default.
- W2888578377 hasRelatedWork W2373226427 @default.
- W2888578377 hasRelatedWork W2387456186 @default.
- W2888578377 hasRelatedWork W2388730008 @default.
- W2888578377 hasRelatedWork W2393133974 @default.
- W2888578377 hasRelatedWork W2419356870 @default.
- W2888578377 hasRelatedWork W757206253 @default.
- W2888578377 hasVolume "97" @default.
- W2888578377 isParatext "false" @default.
- W2888578377 isRetracted "false" @default.
- W2888578377 magId "2888578377" @default.
- W2888578377 workType "article" @default.