FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888680705> ?p ?o ?g. }

• W2888680705 endingPage "258" @default.
• W2888680705 startingPage "253" @default.
• W2888680705 abstract "There is a growing body of evidence that cumulative hyperglycemic exposure plays a central role in the development and progression of atherosclerotic cardiovascular disease in diabetic patients. Monosaccharides, such as glucose, fructose, and glyceraldehyde can react non-enzymatically with amino groups of proteins, lipids, nucleic acids to form senescent macromolecules termed advanced glycation end products (AGEs), whose formation and accumulation has been known to progress in diabetic patients, especially in those with a long history of disease. The sustained accumulation of AGEs could contribute to the phenomenon of metabolic memory or legacy effects observed in long-term follow-up clinical studies of diabetic patients. AGE modification alters the structural integrity and function of various types of macromolecules, and interaction of AGEs with a receptor for AGEs (RAGE) has been shown to evoke inflammatory and thrombotic reactions. Therefore, the AGE–RAGE axis is a novel therapeutic target of atherosclerotic cardiovascular disease in diabetic patients. In this paper, we briefly review the pathological role of AGEs and their receptor RAGE system in atherosclerotic cardiovascular disease, including peripheral artery disease and discuss the clinical utility of measuring AGEs in evaluating the severity of atherosclerosis in patients with diabetes." @default.
• W2888680705 created "2018-08-31" @default.
• W2888680705 creator A5030113532 @default.
• W2888680705 creator A5086054133 @default.
• W2888680705 date "2018-09-25" @default.
• W2888680705 modified "2023-10-16" @default.
• W2888680705 title "Role of Hyperglycemia-Induced Advanced Glycation End Product (AGE) Accumulation in Atherosclerosis" @default.
• W2888680705 cites W1752045965 @default.
• W2888680705 cites W1963535697 @default.
• W2888680705 cites W1975224849 @default.
• W2888680705 cites W1976005877 @default.
• W2888680705 cites W1978210980 @default.
• W2888680705 cites W1982878086 @default.
• W2888680705 cites W2000258452 @default.
• W2888680705 cites W2006165608 @default.
• W2888680705 cites W2006724072 @default.
• W2888680705 cites W2011594751 @default.
• W2888680705 cites W2013467526 @default.
• W2888680705 cites W2022725096 @default.
• W2888680705 cites W2023025903 @default.
• W2888680705 cites W2031101829 @default.
• W2888680705 cites W2032510274 @default.
• W2888680705 cites W2045610739 @default.
• W2888680705 cites W2047724792 @default.
• W2888680705 cites W2052055930 @default.
• W2888680705 cites W2052914045 @default.
• W2888680705 cites W2055823448 @default.
• W2888680705 cites W2056258976 @default.
• W2888680705 cites W2057180656 @default.
• W2888680705 cites W2057961754 @default.
• W2888680705 cites W2058597871 @default.
• W2888680705 cites W2063611823 @default.
• W2888680705 cites W2066963386 @default.
• W2888680705 cites W2068900191 @default.
• W2888680705 cites W2070708034 @default.
• W2888680705 cites W2071259499 @default.
• W2888680705 cites W2072726731 @default.
• W2888680705 cites W2072878932 @default.
• W2888680705 cites W2076633296 @default.
• W2888680705 cites W2080937631 @default.
• W2888680705 cites W2081901990 @default.
• W2888680705 cites W2085350659 @default.
• W2888680705 cites W2089973934 @default.
• W2888680705 cites W2094411506 @default.
• W2888680705 cites W2096626379 @default.
• W2888680705 cites W2096857883 @default.
• W2888680705 cites W2097899363 @default.
• W2888680705 cites W2111037557 @default.
• W2888680705 cites W2112706810 @default.
• W2888680705 cites W2112715147 @default.
• W2888680705 cites W2114419186 @default.
• W2888680705 cites W2115060813 @default.
• W2888680705 cites W2115944392 @default.
• W2888680705 cites W2124425532 @default.
• W2888680705 cites W2125588985 @default.
• W2888680705 cites W2126919962 @default.
• W2888680705 cites W2129292709 @default.
• W2888680705 cites W2129651625 @default.
• W2888680705 cites W2129668944 @default.
• W2888680705 cites W2132176130 @default.
• W2888680705 cites W2133857970 @default.
• W2888680705 cites W2134518165 @default.
• W2888680705 cites W2138329655 @default.
• W2888680705 cites W2138561622 @default.
• W2888680705 cites W2142870997 @default.
• W2888680705 cites W2145922680 @default.
• W2888680705 cites W2146121284 @default.
• W2888680705 cites W2146514589 @default.
• W2888680705 cites W2149639635 @default.
• W2888680705 cites W2153288821 @default.
• W2888680705 cites W2155075876 @default.
• W2888680705 cites W2156485867 @default.
• W2888680705 cites W2161682643 @default.
• W2888680705 cites W2171294019 @default.
• W2888680705 cites W2176343920 @default.
• W2888680705 cites W2313996541 @default.
• W2888680705 cites W2331274940 @default.
• W2888680705 cites W2335563658 @default.
• W2888680705 cites W2346630656 @default.
• W2888680705 cites W2394031532 @default.
• W2888680705 cites W2410579803 @default.
• W2888680705 cites W2416545281 @default.
• W2888680705 cites W2419452272 @default.
• W2888680705 cites W2467097643 @default.
• W2888680705 cites W2468443240 @default.
• W2888680705 cites W2507364480 @default.
• W2888680705 cites W2510751088 @default.
• W2888680705 cites W2536497136 @default.
• W2888680705 cites W2587108949 @default.
• W2888680705 cites W2589588206 @default.
• W2888680705 cites W2608035323 @default.
• W2888680705 cites W2624277477 @default.
• W2888680705 cites W2748400555 @default.
• W2888680705 cites W2791785688 @default.
• W2888680705 cites W2801059248 @default.
• W2888680705 cites W4255839779 @default.
• W2888680705 cites W46879738 @default.
• W2888680705 doi "https://doi.org/10.3400/avd.ra.18-00070" @default.

• next