FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888696052> ?p ?o ?g. }

• W2888696052 abstract "In this pooled 2-center series LINAC radiosurgery (SRS) has been applied as a treatment option for a subset of refractory trigeminal neuralgia (TN) patients. This study approached to retrospectively assess the efficacy and safety of LINAC SRS and to provide a brief overview addressed to the technical development from frame-based towards frameless robotic SRS. From 2001 to 2017 n = 55 patients (pts) were treated, n = 28 were female (51%), mean age: 66 years (range 36–93 years); TN etiology: 37 classic TN, 15 multiple sclerosis (MS)-related TN, 2 symptomatic TN, and 1 atypical TN. Previous treatment was present in n = 35 (63.6%) pts. (some multiple or combined) with n = 23 microsurgical vascular decompression and n = 17 percutaneous retrogasserian rhizotomy. A 6 MV LINAC (4–5 mm collimators) was applied in all pts. (n = 26 framebased - n = 29 frameless robotic). The dorsal root entry zone (DREZ) was targeted in n = 35 cases and the retrogasserian target in n = 20 pts. with a homogeneous dose for the entire study cohort (90 Gy). SRS outcome was measured using the Barrow Neurological Institute (BNI) score for pain and hypaesthesia and statistically evaluated by univariate and multivariate analyzes. Mean follow-up (FU) was 30 months (2 lost FU); the total rate of post SRS BNI pain I-IIIa (=painfree w or w/o medication) was 69% (88% for the classic TN pts), 29% (38.8% classic TN) were classified as BNI pain I-II (=painfree w/o medication). A BNI hypaesthesia II-III was present in 9.4% (n = 5) and BNI hypaesthesia IV in n = 2. Between groups analysis demonstrated no correlation of SRS responsiveness with age, gender, MS- or not MS-associated TN, previous surgery, framebased/frameless robotic SRS. DREZ targeting significantly better suppressed TN compared to RG targeting (p = 0.01). Additionally, a statistical trend for a better BNI pain outcome (p = 0.07) along with a significant increase in BNI hypaesthesia (p = 0.01) was found when using a larger partial trigeminal 70 Gy volume. Our retrospective analysis support LINAC SRS as an effective and safe treatment option in TN. Frameless robotic SRS of TN is safe when using a dedicated LINAC system. A target definition closer to the brainstem and tendencially a larger target volume were associated with a better outcome for pain." @default.
• W2888696052 created "2018-08-31" @default.
• W2888696052 creator A5004090819 @default.
• W2888696052 creator A5022187688 @default.
• W2888696052 creator A5031402263 @default.
• W2888696052 creator A5052423504 @default.
• W2888696052 creator A5066764346 @default.
• W2888696052 creator A5088659595 @default.
• W2888696052 date "2018-08-22" @default.
• W2888696052 modified "2023-10-02" @default.
• W2888696052 title "LINAC stereotactic radiosurgery for trigeminal neuralgia –retrospective two-institutional examination of treatment outcomes" @default.
• W2888696052 cites W1497415175 @default.
• W2888696052 cites W1544060214 @default.
• W2888696052 cites W1592693372 @default.
• W2888696052 cites W1726650576 @default.
• W2888696052 cites W1972494672 @default.
• W2888696052 cites W1981195699 @default.
• W2888696052 cites W1992556696 @default.
• W2888696052 cites W1998586326 @default.
• W2888696052 cites W2000414879 @default.
• W2888696052 cites W2007822211 @default.
• W2888696052 cites W2008295678 @default.
• W2888696052 cites W2008584212 @default.
• W2888696052 cites W2009552512 @default.
• W2888696052 cites W2022507362 @default.
• W2888696052 cites W2024362274 @default.
• W2888696052 cites W2025396856 @default.
• W2888696052 cites W2032528950 @default.
• W2888696052 cites W2035762964 @default.
• W2888696052 cites W2048779318 @default.
• W2888696052 cites W2048966310 @default.
• W2888696052 cites W2050784070 @default.
• W2888696052 cites W2053393211 @default.
• W2888696052 cites W2057097662 @default.
• W2888696052 cites W2069232648 @default.
• W2888696052 cites W2117086992 @default.
• W2888696052 cites W2119479825 @default.
• W2888696052 cites W2130000029 @default.
• W2888696052 cites W2142081272 @default.
• W2888696052 cites W2143067151 @default.
• W2888696052 cites W2144567223 @default.
• W2888696052 cites W2147554615 @default.
• W2888696052 cites W2159632847 @default.
• W2888696052 cites W2168844331 @default.
• W2888696052 cites W2192750392 @default.
• W2888696052 cites W2275266320 @default.
• W2888696052 cites W2292865345 @default.
• W2888696052 cites W2305977931 @default.
• W2888696052 cites W2312850028 @default.
• W2888696052 cites W2313494828 @default.
• W2888696052 cites W2409386617 @default.
• W2888696052 cites W2560383735 @default.
• W2888696052 cites W2589800349 @default.
• W2888696052 cites W2596612105 @default.
• W2888696052 cites W2801085490 @default.
• W2888696052 cites W4233064283 @default.
• W2888696052 cites W4302561478 @default.
• W2888696052 doi "https://doi.org/10.1186/s13014-018-1102-2" @default.
• W2888696052 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6106738" @default.
• W2888696052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30134992" @default.
• W2888696052 hasPublicationYear "2018" @default.
• W2888696052 type Work @default.
• W2888696052 sameAs 2888696052 @default.
• W2888696052 citedByCount "18" @default.
• W2888696052 countsByYear W28886960522019 @default.
• W2888696052 countsByYear W28886960522020 @default.
• W2888696052 countsByYear W28886960522021 @default.
• W2888696052 countsByYear W28886960522022 @default.
• W2888696052 countsByYear W28886960522023 @default.
• W2888696052 crossrefType "journal-article" @default.
• W2888696052 hasAuthorship W2888696052A5004090819 @default.
• W2888696052 hasAuthorship W2888696052A5022187688 @default.
• W2888696052 hasAuthorship W2888696052A5031402263 @default.
• W2888696052 hasAuthorship W2888696052A5052423504 @default.
• W2888696052 hasAuthorship W2888696052A5066764346 @default.
• W2888696052 hasAuthorship W2888696052A5088659595 @default.
• W2888696052 hasBestOaLocation W28886960521 @default.
• W2888696052 hasConcept C105702510 @default.
• W2888696052 hasConcept C121332964 @default.
• W2888696052 hasConcept C140530291 @default.
• W2888696052 hasConcept C141071460 @default.
• W2888696052 hasConcept C142424586 @default.
• W2888696052 hasConcept C2776651944 @default.
• W2888696052 hasConcept C2779846724 @default.
• W2888696052 hasConcept C2780355897 @default.
• W2888696052 hasConcept C2780387249 @default.
• W2888696052 hasConcept C2780504541 @default.
• W2888696052 hasConcept C2989005 @default.
• W2888696052 hasConcept C509974204 @default.
• W2888696052 hasConcept C71924100 @default.
• W2888696052 hasConcept C87355193 @default.
• W2888696052 hasConceptScore W2888696052C105702510 @default.
• W2888696052 hasConceptScore W2888696052C121332964 @default.
• W2888696052 hasConceptScore W2888696052C140530291 @default.
• W2888696052 hasConceptScore W2888696052C141071460 @default.
• W2888696052 hasConceptScore W2888696052C142424586 @default.
• W2888696052 hasConceptScore W2888696052C2776651944 @default.
• W2888696052 hasConceptScore W2888696052C2779846724 @default.
• W2888696052 hasConceptScore W2888696052C2780355897 @default.
• W2888696052 hasConceptScore W2888696052C2780387249 @default.

• next