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- W2888730596 abstract "Abstract Perforation of the esophagus is a potentially serious and life-threatening medical emergency. Given the diverse etiologies and wide variety in clinical presentations of the perforated esophagus, the managing physician must possess a thorough understanding of the principles behind its treatment, as well as have access to an array of therapeutic tools, to provide an optimal outcome. Surgical therapy has occupied a prominent place in the management armamentarium of esophageal perforation since Norman Barrett reported the first case of successful primary repair in 1946. Over the subsequent decades, surgical techniques have been developed and refined, and improvements in antibiotics, critical care, radiologic imaging, and percutaneous interventions have evolved. More recently, nonoperative and endoscopic approaches have been introduced as alternatives to surgery in appropriately selected patients, further improving the ability to treat this condition. Despite these advances, the morbidity and mortality following perforation of the esophagus remain high, especially in cases of diagnostic delay, underscoring the importance of prompt recognition and appropriate treatment of this malady. Therefore considerable clinical judgment is required on the part of the managing physician because treatment decisions may have a major impact on outcomes." @default.
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- W2888730596 date "2019-01-01" @default.
- W2888730596 modified "2023-10-16" @default.
- W2888730596 title "Etiology and Management of Esophageal Perforation" @default.
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- W2888730596 doi "https://doi.org/10.1016/b978-0-323-40232-3.00048-0" @default.
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