FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888787100> ?p ?o ?g. }

• W2888787100 endingPage "1109" @default.
• W2888787100 startingPage "1105" @default.
• W2888787100 abstract "ABSTRACT: Theileria equi is an infectious hemoprotozoan agent of equine piroplasmosis, a disease that has severe economic and sanitary impact internationally. In addition to its common clinical features, piroplasmosis can cause gestational losses and neonatal damage, which makes neonates susceptible to this disease. The aim of this study was to evaluate the dynamics of humoral immune response to recombinant EMA-2 of T. equi in pregnant mares and foals, as well as the transfer of vaccine antibodies through the colostrum ingested by sucking foals. For vaccine production, the EMA-2 expression gene was cloned and expressed in the yeast species, Pichia pastoris. Thirty-six horses were used, of which 18 were pregnant mares and 18 were foals. The mares were divided into control and vaccinated groups, and the vaccinated group received three doses of rEMA-2 every 21 days starting at 300 days of gestation. Foals from vaccinated and control groups were evaluated until the sixth month of life. The production of antibodies by foals on the rEMA-2 vaccination schedule was also evaluated from the second month of life. Foals in the vaccinated group had received three doses of the vaccine every 21 days. The method used to evaluate serum and colostrum samples was indirect ELISA, and plates were sensitized with the rEMA-2 protein. At the end of the vaccination schedule, vaccinated mares showed a 2.3-fold increase in antibody levels when compared to baseline values. The colostrum of vaccinated mares presented antibody levels of 1.0432±0.33. Foals delivered by vaccinated mares presented levels of antibodies greater than those of foals delivered by control mares after their first time sucking (at about twelve hours after birth). Foals vaccinated in the second month of life showed an 8.3-fold increase in antibody levels when compared to baseline values. The vaccination schedule with rEMA-2 was able to stimulate humoral immunity in pregnant mares. Vaccine immunoglobins were concentrated in the colostrum of vaccinated mares and foals delivered by these mares showed an increase in serum levels of vaccine antibodies after the first-time sucking." @default.
• W2888787100 created "2018-09-07" @default.
• W2888787100 creator A5015117055 @default.
• W2888787100 creator A5029575492 @default.
• W2888787100 creator A5033660680 @default.
• W2888787100 creator A5059493869 @default.
• W2888787100 creator A5059805217 @default.
• W2888787100 creator A5065934034 @default.
• W2888787100 creator A5077084027 @default.
• W2888787100 creator A5078197371 @default.
• W2888787100 date "2018-06-01" @default.
• W2888787100 modified "2023-10-16" @default.
• W2888787100 title "Dynamics of humoral immune response in pregnant mares and foals vaccinated with Theileria equi recombinant EMA-2" @default.
• W2888787100 cites W1590546703 @default.
• W2888787100 cites W1850402163 @default.
• W2888787100 cites W1984642581 @default.
• W2888787100 cites W2038027767 @default.
• W2888787100 cites W2042599622 @default.
• W2888787100 cites W2048793011 @default.
• W2888787100 cites W2052424882 @default.
• W2888787100 cites W2067939837 @default.
• W2888787100 cites W2084190709 @default.
• W2888787100 cites W2133331047 @default.
• W2888787100 cites W2186373932 @default.
• W2888787100 cites W4238923034 @default.
• W2888787100 cites W4253981044 @default.
• W2888787100 cites W972418317 @default.
• W2888787100 doi "https://doi.org/10.1590/1678-5150-pvb-5321" @default.
• W2888787100 hasPublicationYear "2018" @default.
• W2888787100 type Work @default.
• W2888787100 sameAs 2888787100 @default.
• W2888787100 citedByCount "0" @default.
• W2888787100 crossrefType "journal-article" @default.
• W2888787100 hasAuthorship W2888787100A5015117055 @default.
• W2888787100 hasAuthorship W2888787100A5029575492 @default.
• W2888787100 hasAuthorship W2888787100A5033660680 @default.
• W2888787100 hasAuthorship W2888787100A5059493869 @default.
• W2888787100 hasAuthorship W2888787100A5059805217 @default.
• W2888787100 hasAuthorship W2888787100A5065934034 @default.
• W2888787100 hasAuthorship W2888787100A5077084027 @default.
• W2888787100 hasAuthorship W2888787100A5078197371 @default.
• W2888787100 hasBestOaLocation W28887871001 @default.
• W2888787100 hasConcept C136764020 @default.
• W2888787100 hasConcept C159047783 @default.
• W2888787100 hasConcept C159654299 @default.
• W2888787100 hasConcept C203014093 @default.
• W2888787100 hasConcept C22070199 @default.
• W2888787100 hasConcept C2776111823 @default.
• W2888787100 hasConcept C2776869253 @default.
• W2888787100 hasConcept C2779073587 @default.
• W2888787100 hasConcept C41008148 @default.
• W2888787100 hasConcept C54355233 @default.
• W2888787100 hasConcept C71924100 @default.
• W2888787100 hasConcept C71928629 @default.
• W2888787100 hasConcept C86803240 @default.
• W2888787100 hasConcept C8891405 @default.
• W2888787100 hasConceptScore W2888787100C136764020 @default.
• W2888787100 hasConceptScore W2888787100C159047783 @default.
• W2888787100 hasConceptScore W2888787100C159654299 @default.
• W2888787100 hasConceptScore W2888787100C203014093 @default.
• W2888787100 hasConceptScore W2888787100C22070199 @default.
• W2888787100 hasConceptScore W2888787100C2776111823 @default.
• W2888787100 hasConceptScore W2888787100C2776869253 @default.
• W2888787100 hasConceptScore W2888787100C2779073587 @default.
• W2888787100 hasConceptScore W2888787100C41008148 @default.
• W2888787100 hasConceptScore W2888787100C54355233 @default.
• W2888787100 hasConceptScore W2888787100C71924100 @default.
• W2888787100 hasConceptScore W2888787100C71928629 @default.
• W2888787100 hasConceptScore W2888787100C86803240 @default.
• W2888787100 hasConceptScore W2888787100C8891405 @default.
• W2888787100 hasIssue "6" @default.
• W2888787100 hasLocation W28887871001 @default.
• W2888787100 hasLocation W28887871002 @default.
• W2888787100 hasOpenAccess W2888787100 @default.
• W2888787100 hasPrimaryLocation W28887871001 @default.
• W2888787100 hasRelatedWork W155301942 @default.
• W2888787100 hasRelatedWork W189741798 @default.
• W2888787100 hasRelatedWork W1933000609 @default.
• W2888787100 hasRelatedWork W1952555484 @default.
• W2888787100 hasRelatedWork W2019574320 @default.
• W2888787100 hasRelatedWork W2031542135 @default.
• W2888787100 hasRelatedWork W3048051248 @default.
• W2888787100 hasRelatedWork W4206914007 @default.
• W2888787100 hasRelatedWork W4221063257 @default.
• W2888787100 hasRelatedWork W2415727916 @default.
• W2888787100 hasVolume "38" @default.
• W2888787100 isParatext "false" @default.
• W2888787100 isRetracted "false" @default.
• W2888787100 magId "2888787100" @default.
• W2888787100 workType "article" @default.