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- W2888793489 abstract "After partial venous occlusion of dog's femoral vein until 60% of its initial cross section for 90 min. we have observed a decrease in plasminogen activator content (t-PA) in the pre-occlusion segment and an increase of prostacyclin like activity (PLA) in the post -occlusion segment (in press). In this work and in order to try to find an ultra-structural basis for these findings, we carried out observations of the constricted segments with transmission and scanning E.M. (n=10). We observed that : -1) endothelial cells were maintained in place, with minimal ultrastructural changes, namely a small increase in vaccuolization ;-2) there was massive subendothelial deposition of leucocytes, predominantly polimorphonuclears, which permeate internal elastic lamina and were also found in subjacent structures; -3) platelets were rarely seen and platelets agregates were never found. Autologous Indium labelled platelets injection confirmed in vivo these findnigs (n=10). We conclude that in partial venous occlusion, platelet deposition and endothelial cell descamation are not initiating factors in changes observed at t-PA and PLA vessel wall levels, although the role of white blood cells will need further investigation." @default.
- W2888793489 created "2018-09-07" @default.
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- W2888793489 date "1987-01-01" @default.
- W2888793489 modified "2023-09-26" @default.
- W2888793489 title "LEUCOCYTES AND PLATELETS DEPOSITION CN ENDOTHELIAL SURFACE INDUCED BY PARTIAL VENOUS OCCLUSION.AN ULTRASTRUCTURAL STUDY IN THE DOG" @default.
- W2888793489 doi "https://doi.org/10.1055/s-0038-1644433" @default.
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