Matches in SemOpenAlex for { <https://semopenalex.org/work/W2888815005> ?p ?o ?g. }
- W2888815005 endingPage "689" @default.
- W2888815005 startingPage "675" @default.
- W2888815005 abstract "Abstract Enzymes have several remarkable properties while offering incredible catalytic power for extensive diversity of cellular reactions, often with fine specificity toward substrates/products and remarkable regulation of catalytic activities. For commercial use, enzymes with improved activities/stability are needed. The areas of biocatalyst improvement are implemented with the use of all available protein chemistry advancements. For modified enzymes, four protein bioengineering approaches are followed: (1) Structure-guided enzymatic protein engineering for specific modifications, (2) Consensus designing to enhance multienzyme activity with changed localization or enzyme folding, (3) Directed evolution by enzyme mutation with the help of sequence libraries having preceding information regarding requisite properties and better variants selection, and (4) In silico or computational protein designing, a relatively unexplored but more valuable and fast-evolving device used to modify enzyme activity. These approaches can be the solution for better utilization of enzymes in commercial conditions where native enzymes have functional shortcomings in terms of enzyme stability and specificity in nonphysiological conditions. Thus, the engineering of native enzymes could be a tool to advance the enzymatic properties for commercial applications." @default.
- W2888815005 created "2018-09-07" @default.
- W2888815005 creator A5007796387 @default.
- W2888815005 creator A5073813379 @default.
- W2888815005 date "2019-01-01" @default.
- W2888815005 modified "2023-09-25" @default.
- W2888815005 title "Enzyme Engineering for Enzyme Activity Improvement" @default.
- W2888815005 cites W1509956720 @default.
- W2888815005 cites W1515209736 @default.
- W2888815005 cites W1532920991 @default.
- W2888815005 cites W1590376353 @default.
- W2888815005 cites W1594663644 @default.
- W2888815005 cites W1868333553 @default.
- W2888815005 cites W1893329979 @default.
- W2888815005 cites W1954202239 @default.
- W2888815005 cites W1965772302 @default.
- W2888815005 cites W1966757283 @default.
- W2888815005 cites W1969492379 @default.
- W2888815005 cites W1974961023 @default.
- W2888815005 cites W1976236461 @default.
- W2888815005 cites W1978119727 @default.
- W2888815005 cites W1980725840 @default.
- W2888815005 cites W1981407107 @default.
- W2888815005 cites W1982792504 @default.
- W2888815005 cites W1984180361 @default.
- W2888815005 cites W1986056153 @default.
- W2888815005 cites W1987696643 @default.
- W2888815005 cites W1990532591 @default.
- W2888815005 cites W1990795007 @default.
- W2888815005 cites W1991854911 @default.
- W2888815005 cites W1993579387 @default.
- W2888815005 cites W1996142946 @default.
- W2888815005 cites W1998109852 @default.
- W2888815005 cites W1999691108 @default.
- W2888815005 cites W2002219567 @default.
- W2888815005 cites W2004926184 @default.
- W2888815005 cites W2005840829 @default.
- W2888815005 cites W2011513747 @default.
- W2888815005 cites W2012948311 @default.
- W2888815005 cites W2015449517 @default.
- W2888815005 cites W2018035699 @default.
- W2888815005 cites W2023271986 @default.
- W2888815005 cites W2024335508 @default.
- W2888815005 cites W2024591656 @default.
- W2888815005 cites W2029298475 @default.
- W2888815005 cites W2032178575 @default.
- W2888815005 cites W2039262558 @default.
- W2888815005 cites W2040211040 @default.
- W2888815005 cites W2040223458 @default.
- W2888815005 cites W2041462402 @default.
- W2888815005 cites W2043855562 @default.
- W2888815005 cites W2044952220 @default.
- W2888815005 cites W2048274228 @default.
- W2888815005 cites W2048765448 @default.
- W2888815005 cites W2049325327 @default.
- W2888815005 cites W2053077463 @default.
- W2888815005 cites W2053878100 @default.
- W2888815005 cites W2054846237 @default.
- W2888815005 cites W2058054649 @default.
- W2888815005 cites W2059143808 @default.
- W2888815005 cites W2059755858 @default.
- W2888815005 cites W2061178897 @default.
- W2888815005 cites W2062242867 @default.
- W2888815005 cites W2062275861 @default.
- W2888815005 cites W2063142847 @default.
- W2888815005 cites W2064474303 @default.
- W2888815005 cites W2069814112 @default.
- W2888815005 cites W2071380042 @default.
- W2888815005 cites W2075097399 @default.
- W2888815005 cites W2076992251 @default.
- W2888815005 cites W2078952503 @default.
- W2888815005 cites W2082260955 @default.
- W2888815005 cites W2085472819 @default.
- W2888815005 cites W2085534722 @default.
- W2888815005 cites W2086506238 @default.
- W2888815005 cites W2089856357 @default.
- W2888815005 cites W2091471707 @default.
- W2888815005 cites W2095249666 @default.
- W2888815005 cites W2095370301 @default.
- W2888815005 cites W2098760862 @default.
- W2888815005 cites W2102599235 @default.
- W2888815005 cites W2104220374 @default.
- W2888815005 cites W2105718579 @default.
- W2888815005 cites W2114182624 @default.
- W2888815005 cites W2117515539 @default.
- W2888815005 cites W2118484018 @default.
- W2888815005 cites W2121398756 @default.
- W2888815005 cites W2122091356 @default.
- W2888815005 cites W2122527879 @default.
- W2888815005 cites W2125214592 @default.
- W2888815005 cites W2128693638 @default.
- W2888815005 cites W2128722373 @default.
- W2888815005 cites W2130775475 @default.
- W2888815005 cites W2133138206 @default.
- W2888815005 cites W2133701300 @default.
- W2888815005 cites W2135211698 @default.
- W2888815005 cites W2136676509 @default.
- W2888815005 cites W2136780852 @default.