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- W2888820753 startingPage "1715" @default.
- W2888820753 abstract "Abstract Poor family cohesion and elevated adolescent aggression are associated with greater alcohol use in adolescence and early adulthood. In addition, evocative gene–environment correlations ( r GEs) can underlie the interplay between offspring characteristics and negative family functioning, contributing to substance use. Gene–environment interplay has rarely been examined in racial/ethnic minority populations. The current study examined adolescents’ polygenic risk scores for aggression in evocative r GEs underlying aggression and family cohesion during adolescence, their contributions to alcohol use in early adulthood ( n = 479), and differences between Mexican American and European American subsamples. Results suggest an evocative r GE between polygenic risk scores, aggression, and low family cohesion, with aggression contributing to low family cohesion over time. Greater family cohesion was associated with lower levels of alcohol use in early adulthood and this association was stronger for Mexican American adolescents compared to European American adolescents. Results are discussed with respect to integration of culture and racial/ethnic minority samples into genetic research and implications for alcohol use." @default.
- W2888820753 created "2018-09-07" @default.
- W2888820753 creator A5020875729 @default.
- W2888820753 creator A5023658386 @default.
- W2888820753 creator A5028644792 @default.
- W2888820753 date "2018-08-31" @default.
- W2888820753 modified "2023-09-27" @default.
- W2888820753 title "Polygenic risk, family cohesion, and adolescent aggression in Mexican American and European American families: Developmental pathways to alcohol use" @default.
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- W2888820753 doi "https://doi.org/10.1017/s0954579418000901" @default.
- W2888820753 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6242761" @default.
- W2888820753 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30168407" @default.
- W2888820753 hasPublicationYear "2018" @default.